Demography of sexually transmitted infections with vertical transmission

Hiromu Ito, Taro Yamamoto and Satoru Morita

Applied Mathematics and Computation, 2019, vol. 348, issue C, 363-370

Abstract: Sexually transmitted infections (STIs) are an ongoing public health concern. Despite many efforts, STIs have not been eradicated. Most STIs are infected through “horizontal” sexual contact and “vertical” mother-to-child transmission. We therefore need to explore the mathematical relationship between horizontal and vertical transmissions, which is necessary for the strategic eradication of STIs. Here, we constructed a simple model to demonstrate the infection dynamics of STIs with vertical transmission. We proposed a new formulation of the basic reproduction number (R0) for STIs over generations, and showed that vertical transmission exerts a smaller effect on the R0 than horizontal transmission. We also performed agent-based simulations to validate our theoretical predictions.

Keywords: Sexually transmitted diseases (STDs); The basic reproduction number (R0); Endemic model; Mother-to-child transmission; Scale-free network (search for similar items in EconPapers)
Date: 2019
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Persistent link: https://EconPapers.repec.org/RePEc:eee:apmaco:v:348:y:2019:i:c:p:363-370

DOI: 10.1016/j.amc.2018.12.002

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