Stationary distribution and probability density function analysis of a stochastic HIV model with cell-to-cell infection

Minmin Lu, Yan Wang and Daqing Jiang

Applied Mathematics and Computation, 2021, vol. 410, issue C

Abstract: In this paper, a stochastic HIV model with CD4+ T-cell proliferation, cell-free infection and cell-to-cell transmission is proposed. By constructing suitable Lyapunov function, we establish the existence of unique and ergodic stationary distribution of the model. Moreover, by using asymptotic analysis and employing the Fokker-Planck equation, we derive the probability density function around the quasi-steady state of the system. Through numerical simulations, the effects of the stochastic perturbation and cell-to-cell infection on model dynamic behavior are investigated, thus the probability density function of the system is also given under the realistic parameter values.

Keywords: HIV infection model; Cell-to-cell infection; Stochastic differential equation; Stationary distribution; Fokker-Planck equation; Probability density function (search for similar items in EconPapers)
Date: 2021
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Citations: View citations in EconPapers (2)

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Persistent link: https://EconPapers.repec.org/RePEc:eee:apmaco:v:410:y:2021:i:c:s0096300321005725

DOI: 10.1016/j.amc.2021.126483

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