Applied DNA visibility graphs: Understanding DNA structure-function relationship in genomics
Kosmas Kosmidis
Physica A: Statistical Mechanics and its Applications, 2025, vol. 663, issue C
Abstract:
DNA sequences have a complex structure that reflects their evolutionary history, such as functional elements, gene modifications, and repetitive segments. To study this structure, mathematical models like DNA walks can be used. DNA walks assign opposite movements to pyrimidines (C, T) and purines (A, G), allowing the application of nonlinear dynamics and complex systems theory. These methods can reveal long-range correlations and genome signatures that are useful for metagenomics. We combined DNA walks and visibility graphs to create DNA visibility graphs (Kosmidis and Hütt, 2023), which can capture correlations in DNA regions and artificial sequences.
Keywords: DNA walks; Visibility graphs; DNA sequences; Network analysis; Sequence composition (search for similar items in EconPapers)
Date: 2025
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Persistent link: https://EconPapers.repec.org/RePEc:eee:phsmap:v:663:y:2025:i:c:s0378437125000883
DOI: 10.1016/j.physa.2025.130436
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