Effect of Dietary Supplementation of Mycotoxin Adsorbent on Laying Performance and Oviduct Health of Laying Hens in Aflatoxin B1 Exposed

Yi Wei, Meng Sun, Jingjing Sun, Qiuyu Jiang and Bingkun Zhang ()
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Yi Wei: State Key Laboratory of Animal Nutrition and Feeding, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China
Meng Sun: State Key Laboratory of Animal Nutrition and Feeding, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China
Jingjing Sun: State Key Laboratory of Animal Nutrition and Feeding, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China
Qiuyu Jiang: State Key Laboratory of Animal Nutrition and Feeding, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China
Bingkun Zhang: State Key Laboratory of Animal Nutrition and Feeding, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China

Agriculture, 2024, vol. 14, issue 12, 1-10

Abstract: Aflatoxin contamination causes huge economic losses in animal husbandry by inhibiting growth and performance. The addition of mycotoxin binders to contaminate diets has been widely used for mycotoxin removal. Bentonite and yeast cell walls have received increasing attention as efficient and low-cost adsorbents. This study utilizes a mycotoxin adsorbent (MAB) to bind Aflatoxin B1 (AFB1) in feed. The trial was a randomized trial design, with 240 forty-three-week-old Hy-line Brown laying hens allocated to four groups, and with 80 birds in each group. The three diets used in the experiment were: (1) control diet; (2) control diet + 0.2 mg/kg AFB1; (3) control diet+ 0.2 mg/kg AFB1 + 2.0 g/kg MAB. All laying hens were fed a basal diet for one week. The feeding trial lasted for 12 weeks followed by a 1-week adaptation phase. The results show that laying hens fed the AFB1-contaminated diet had decreased performance and egg quality and reduced oviduct index and length. Blood biochemical parameters show that AFB1 leads to increased serum alanine aminotransferase (ALT) and aspartate aminotransferase (AST) levels. Compared to the control diet groups, exposure to the AFB1-contaminated diet resulted in liver and uterine tissue damage, mainly manifested by inflammatory infiltration. Compared with AFB1-contaminated diets, liver and uterine damage was alleviated with the AFB1 + MAB diet and partially restored to control levels. At the same time, we also observed that AFB1 treatment up-regulated the expression of Interferon-α ( IFN-α ), CASPASE-3 , and CASPASE-8 in the uterus of laying hens, but this phenomenon was alleviated after adding the MAB. Therefore, under the experimental conditions, supplementation of MAB in AFB1-contaminated hen diets was an effective intervention to reduce aflatoxin toxicity.

Keywords: aflatoxin B1; mycotoxin adsorbent; egg quality; uterine health (search for similar items in EconPapers)
JEL-codes: Q1 Q10 Q11 Q12 Q13 Q14 Q15 Q16 Q17 Q18 (search for similar items in EconPapers)
Date: 2024
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