Robust Genetic Circuit Design: A Mixed and IQC Analysis

Ruijuan Chen, Wei Pan, Dongfei Fu and Xin He

Advances in Mathematical Physics, 2017, vol. 2017, 1-6

Abstract:

This paper considers the problem of designing a genetic circuit which is robust to noise effect. To achieve this goal, a mixed and Integral Quadratic Constraints (IQC) approach is proposed. In order to minimize the effects of external noise on the genetic regulatory network in terms of norm, a design procedure of Hill coefficients in the promoters is presented. The IQC approach is introduced to analyze and guarantee the stability of the designed circuit.

Date: 2017
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Persistent link: https://EconPapers.repec.org/RePEc:hin:jnlamp:5757943

DOI: 10.1155/2017/5757943

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