Controlling the double helix

Gary Felsenfeld () and Mark Groudine ()
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Gary Felsenfeld: Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health
Mark Groudine: Fred Hutchinson Cancer Research Center

Nature, 2003, vol. 421, issue 6921, 448-453

Abstract: Abstract Chromatin is the complex of DNA and proteins in which the genetic material is packaged inside the cells of organisms with nuclei. Chromatin structure is dynamic and exerts profound control over gene expression and other fundamental cellular processes. Changes in its structure can be inherited by the next generation, independent of the DNA sequence itself.

Date: 2003
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DOI: 10.1038/nature01411

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