NAD captureSeq indicates NAD as a bacterial cap for a subset of regulatory RNAs

Hana Cahová, Marie-Luise Winz, Katharina Höfer, Gabriele Nübel and Andres Jäschke ()
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Hana Cahová: Institute of Pharmacy and Molecular Biotechnology (IPMB), Heidelberg University, 69120 Heidelberg, Germany
Marie-Luise Winz: Institute of Pharmacy and Molecular Biotechnology (IPMB), Heidelberg University, 69120 Heidelberg, Germany
Katharina Höfer: Institute of Pharmacy and Molecular Biotechnology (IPMB), Heidelberg University, 69120 Heidelberg, Germany
Gabriele Nübel: Institute of Pharmacy and Molecular Biotechnology (IPMB), Heidelberg University, 69120 Heidelberg, Germany
Andres Jäschke: Institute of Pharmacy and Molecular Biotechnology (IPMB), Heidelberg University, 69120 Heidelberg, Germany

Nature, 2015, vol. 519, issue 7543, 374-377

Abstract: A newly developed method, NAD captureSeq, has been used to show that bacteria cap the 5′-ends of some RNAs to protect against degradation, much as happens with eukaryotic messenger RNAs, although with a different modification: nicotinamide adenine dinucleotide.

Date: 2015
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DOI: 10.1038/nature14020

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