RETRACTED ARTICLE: A mechanism for the suppression of homologous recombination in G1 cells

Alexandre Orthwein, Sylvie M. Noordermeer, Marcus D. Wilson, Sébastien Landry, Radoslav I. Enchev, Alana Sherker, Meagan Munro, Jordan Pinder, Jayme Salsman, Graham Dellaire, Bing Xia, Matthias Peter and Daniel Durocher ()
Additional contact information
Alexandre Orthwein: The Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, 600 University Avenue
Sylvie M. Noordermeer: The Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, 600 University Avenue
Marcus D. Wilson: The Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, 600 University Avenue
Sébastien Landry: The Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, 600 University Avenue
Radoslav I. Enchev: ETH Zurich, Institute of Biochemistry
Alana Sherker: The Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, 600 University Avenue
Meagan Munro: The Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, 600 University Avenue
Jordan Pinder: Dalhousie University
Jayme Salsman: Dalhousie University
Graham Dellaire: Dalhousie University
Bing Xia: Rutgers Cancer Institute of New Jersey and Robert Wood Johnson Medical School, Rutgers, The State University of New Jersey
Matthias Peter: ETH Zurich, Institute of Biochemistry
Daniel Durocher: The Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, 600 University Avenue

Nature, 2015, vol. 528, issue 7582, 422-426

Abstract: A mechanism for the repression of homologous recombination in G1, the stage of the cell cycle preceding replication, is determined; the critical aspects are the interaction between BRCA1 and PALB2–BRCA2, and suppression of DNA-end resection.

Date: 2015
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DOI: 10.1038/nature16142

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