Cascading MutS and MutL sliding clamps control DNA diffusion to activate mismatch repair

Jiaquan Liu, Jeungphill Hanne, Brooke M. Britton, Jared Bennett, Daehyung Kim, Jong-Bong Lee () and Richard Fishel ()
Additional contact information
Jiaquan Liu: The Ohio State University Wexner Medical Center
Jeungphill Hanne: The Ohio State University Wexner Medical Center
Brooke M. Britton: The Ohio State University Wexner Medical Center
Jared Bennett: The Ohio State University Wexner Medical Center
Daehyung Kim: Pohang University of Science and Technology (POSTECH)
Jong-Bong Lee: Pohang University of Science and Technology (POSTECH)
Richard Fishel: The Ohio State University Wexner Medical Center

Nature, 2016, vol. 539, issue 7630, 583-587

Abstract: MutS and MutL—the highly conserved core proteins responsible for the repair of mismatched DNA—form sequential stable sliding clamps that together modulate one-dimensional diffusion along the DNA and, with MutH, facilitate the search for a distant excision initiation site.

Date: 2016
References: Add references at CitEc
Citations: View citations in EconPapers (3)

Downloads: (external link)
https://www.nature.com/articles/nature20562 Abstract (text/html)
Access to the full text of the articles in this series is restricted.

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:nat:nature:v:539:y:2016:i:7630:d:10.1038_nature20562

Ordering information: This journal article can be ordered from
https://www.nature.com/

DOI: 10.1038/nature20562

Access Statistics for this article

Nature is currently edited by Magdalena Skipper

More articles in Nature from Nature
Bibliographic data for series maintained by Sonal Shukla () and Springer Nature Abstracting and Indexing ().