SLAMF7 is critical for phagocytosis of haematopoietic tumour cells via Mac-1 integrin
Jun Chen,
Ming-Chao Zhong,
Huaijian Guo,
Dominique Davidson,
Sabrin Mishel,
Yan Lu,
Inmoo Rhee,
Luis-Alberto Pérez-Quintero,
Shaohua Zhang,
Mario-Ernesto Cruz-Munoz,
Ning Wu,
Donald C. Vinh,
Meenal Sinha,
Virginie Calderon,
Clifford A. Lowell,
Jayne S. Danska and
André Veillette ()
Additional contact information
Jun Chen: Laboratory of Molecular Oncology, Institut de recherches cliniques de Montréal (IRCM)
Ming-Chao Zhong: Laboratory of Molecular Oncology, Institut de recherches cliniques de Montréal (IRCM)
Huaijian Guo: Laboratory of Molecular Oncology, Institut de recherches cliniques de Montréal (IRCM)
Dominique Davidson: Laboratory of Molecular Oncology, Institut de recherches cliniques de Montréal (IRCM)
Sabrin Mishel: Hospital for Sick Children
Yan Lu: Laboratory of Molecular Oncology, Institut de recherches cliniques de Montréal (IRCM)
Inmoo Rhee: Laboratory of Molecular Oncology, Institut de recherches cliniques de Montréal (IRCM)
Luis-Alberto Pérez-Quintero: Laboratory of Molecular Oncology, Institut de recherches cliniques de Montréal (IRCM)
Shaohua Zhang: Laboratory of Molecular Oncology, Institut de recherches cliniques de Montréal (IRCM)
Mario-Ernesto Cruz-Munoz: Laboratory of Molecular Oncology, Institut de recherches cliniques de Montréal (IRCM)
Ning Wu: Laboratory of Molecular Oncology, Institut de recherches cliniques de Montréal (IRCM)
Donald C. Vinh: Infectious Disease Susceptibility Program, McGill University Health Centre (MUHC) and Research Institute-MUHC (RI-MUHC)
Meenal Sinha: University of California San Francisco
Virginie Calderon: Bioinformatics Core Facility, Institut de recherches cliniques de Montréal (IRCM)
Clifford A. Lowell: University of California San Francisco
Jayne S. Danska: Hospital for Sick Children
André Veillette: Laboratory of Molecular Oncology, Institut de recherches cliniques de Montréal (IRCM)
Nature, 2017, vol. 544, issue 7651, 493-497
Abstract:
The identification of homotypic SLAMF7 interactions responsible for haematopoietic tumour cell phagocytosis by macrophages when the inhibitory receptor/ligand interaction of SIRPα/CD47 is blocked therapeutically.
Date: 2017
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Persistent link: https://EconPapers.repec.org/RePEc:nat:nature:v:544:y:2017:i:7651:d:10.1038_nature22076
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DOI: 10.1038/nature22076
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