Deletion of a mycobacterial divisome factor collapses single-cell phenotypic heterogeneity

E. Hesper Rego (), Rebecca E. Audette and Eric J. Rubin ()
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E. Hesper Rego: Harvard T.H. Chan School of Public Health
Rebecca E. Audette: Harvard T.H. Chan School of Public Health
Eric J. Rubin: Harvard T.H. Chan School of Public Health

Nature, 2017, vol. 546, issue 7656, 153-157

Abstract: The mycobacterial protein LamA functions as an inhibitor of cell wall synthesis at the nascent cell pole, contributing to asymmetry in polar growth, and could represent a much-needed target for the development of anti-tuberculosis therapies.

Date: 2017
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DOI: 10.1038/nature22361

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