Iron deficiency in pregnant mice causes XY embryos to develop with female characteristics

Shannon Dupont and Blanche Capel ()

Nature, 2025, vol. 643, issue 8070, 45-46

Abstract: In mice, a lack of maternal iron impairs an iron-dependent enzyme that activates the male sex-determining gene, causing some XY embryos to develop ovaries.

Keywords: Developmental biology; Epigenetics; Molecular biology (search for similar items in EconPapers)
Date: 2025
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DOI: 10.1038/d41586-025-01456-7

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