Evaluation of the Treatment Tradeoff Method in Rectal Cancer Patients: Is Surgery Preference Related to Outcome Utilities?

Ercolie R. Bossema, Corrie A. M. Marijnen, Monique C. M. Baas-Thijssen, Cock J. H. van de Velde and Anne M. Stiggelbout
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Ercolie R. Bossema: Department of Clinical Oncology, Leiden University Medical Center, the Netherlands, Department of Medical Decision Making, Leiden University Medical Center, the Netherlands
Corrie A. M. Marijnen: Department of Clinical Oncology, Leiden University Medical Center, the Netherlands, Department of Radiotherapy Netherlands Cancer Institute, Amsterdam, the Netherlands
Monique C. M. Baas-Thijssen: Department of Medical Decision Making, Leiden University Medical Center, the Netherlands
Cock J. H. van de Velde: Department of Surgery (CJHvdV), Leiden University Medical Center, the Netherlands
Anne M. Stiggelbout: Department of Medical Decision Making, Leiden University Medical Center, the Netherlands, a.m.stiggelbout@ lumc.nl

Medical Decision Making, 2008, vol. 28, issue 6, 888-898

Abstract: Background. The treatment tradeoff method (TTM) has been developed specifically for decision making at the level of the individual patient. The task is tailored to the clinical decision problem at hand and may therefore be more relevant to patients than methods of outcome valuation. Despite its wide use in oncology research, few methodological studies regarding validity have been conducted. Objective and Methods. The present study evaluates the validity of the TTM in rectal cancer patients who had undergone either 1 of 2 surgery types: 1 requiring a permanent stoma (stoma group) and 1 involving a postoperative risk of fecal incontinence (no-stoma group). The authors relate the surgery preference scores to the utilities of the 2 main surgery outcome states as well as to their utility difference. Results. Surgery preference was more strongly associated with the utility difference ( r > 0.54 in the total patient group) than with the utilities of the surgery outcome states per se ( r

Keywords: patient preferences; treatment tradeoff; probability tradeoff; time tradeoff; utilities. (search for similar items in EconPapers)
Date: 2008
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Persistent link: https://EconPapers.repec.org/RePEc:sae:medema:v:28:y:2008:i:6:p:888-898

DOI: 10.1177/0272989X08317013

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