The Adoption of Cost-Effectiveness Acceptability Curves in Cost-Utility Analyses

Lisa M. Meckley, Dan Greenberg, Joshua T. Cohen and Peter J. Neumann
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Lisa M. Meckley: Center for the Evaluation of Value and Risk in Health, Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, Boston, Massachusetts, lmeckley@tuftsmedicalcenter.org
Dan Greenberg: Department of Health Systems Management, Ben-Gurion University of the Negev, Beer-Sheva, Israel
Joshua T. Cohen: Center for the Evaluation of Value and Risk in Health, Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, Boston, Massachusetts
Peter J. Neumann: Center for the Evaluation of Value and Risk in Health, Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, Boston, Massachusetts

Medical Decision Making, 2010, vol. 30, issue 3, 314-319

Abstract: Background. Cost-effectiveness acceptability curves (CEACs) plot the probability that one health intervention is more cost-effective than alternatives, as a function of societal willingness to pay for additional units of health (e.g., life-years or quality-adjusted life-years gained). Objectives. To quantify the adoption of CEACs in published cost-utility analyses (CUAs), and to identify factors associated with CEAC use. Methods. Data from the Tufts Medical Center Cost-Effectiveness Analysis Registry (www.cearegistry.org), a database with detailed information on approximately 1,400 CUAs published in the peer reviewed literature through 2006, was analyzed. The registry includes data on study origin, study methodology, reporting of results, whether CEACs were presented, and a subjective quality score. Univariate and multivariate logistic regression analyses were used to identify factors predicting CEAC use, from their introduction in 1994 through 2006. Results. Approximately 15% of CUAs published since 1994 present a CEAC. The use of CEACs has increased rapidly in recent years, from 2.1% of published CUAs in 2001 to 32.6% in 2006 (P

Keywords: cost-utility analysis (CUA); quality-adjusted life year (QALY); cost-effectiveness acceptability curve (CEAC); uncertainty analysis. (search for similar items in EconPapers)
Date: 2010
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Persistent link: https://EconPapers.repec.org/RePEc:sae:medema:v:30:y:2010:i:3:p:314-319

DOI: 10.1177/0272989X09344749

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