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Statistics Applied to Clinical Trials

Ton J. Cleophas, Aeilko H. Zwinderman and Toine F. Cleophas
Additional contact information
Ton J. Cleophas: European Interuniversity College of Pharmaceutical Medicine Lyon
Aeilko H. Zwinderman: Academic Medical Center Amsterdam, Department Biostatistics and Epidemiology
Toine F. Cleophas: Technical University

in Springer Books from Springer

Date: 2006
ISBN: 978-1-4020-4650-6
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Chapters in this book:

Ch Chapter 1 Hypotheses, Data, Stratification
Ton J. Cleophas, Aeilko H. Zwinderman and Toine F. Cleophas
Ch Chapter 10 Research Data Closer to Expectation than Compatible with Random Sampling
Ton J. Cleophas, Aeilko H. Zwinderman and Toine F. Cleophas
Ch Chapter 11 Principles of Linear Regression
Ton J. Cleophas, Aeilko H. Zwinderman and Toine F. Cleophas
Ch Chapter 12 Subgroup Analysis Using Multiple Linear Regression: Confounding, Interaction, Synergism
Ton J. Cleophas, Aeilko H. Zwinderman and Toine F. Cleophas
Ch Chapter 13 Curvilinear Regression
Ton J. Cleophas, Aeilko H. Zwinderman and Toine F. Cleophas
Ch Chapter 14 Logistic and Cox Regression, Problems with Regression Modeling, Markow Models
Ton J. Cleophas, Aeilko H. Zwinderman and Toine F. Cleophas
Ch Chapter 15 Regression Modeling for Improved Precision
Ton J. Cleophas, Aeilko H. Zwinderman and Toine F. Cleophas
Ch Chapter 16 Post-Hoc Analyses in Clinical Trials, a Case for Logistic Regression Analysis
Ton J. Cleophas, Aeilko H. Zwinderman and Toine F. Cleophas
Ch Chapter 17 Interaction Effects in Clinical Trials
Ton J. Cleophas, Aeilko H. Zwinderman and Toine F. Cleophas
Ch Chapter 18 Meta-Analysis
Ton J. Cleophas, Aeilko H. Zwinderman and Toine F. Cleophas
Ch Chapter 19 Crossover Studies with Continuous Variables: Power Analysis
Ton J. Cleophas, Aeilko H. Zwinderman and Toine F. Cleophas
Ch Chapter 2 The Analysis of Efficacy Data of Drug Trials
Ton J. Cleophas, Aeilko H. Zwinderman and Toine F. Cleophas
Ch Chapter 20 Crossover Studies with Binary Responses
Ton J. Cleophas, Aeilko H. Zwinderman and Toine F. Cleophas
Ch Chapter 21 Cross-Over Trials Should Not be Used to Test Treatments with Different Chemical Class
Ton J. Cleophas, Aeilko H. Zwinderman and Toine F. Cleophas
Ch Chapter 22 Quality-Of-Life Assessments in Clinical Trials
Ton J. Cleophas, Aeilko H. Zwinderman and Toine F. Cleophas
Ch Chapter 23 Statistical Analysis of Genetic Data
Ton J. Cleophas, Aeilko H. Zwinderman and Toine F. Cleophas
Ch Chapter 24 Relationship Among Statistical Distributions
Ton J. Cleophas, Aeilko H. Zwinderman and Toine F. Cleophas
Ch Chapter 25 Testing Clinical Trials for Randomness
Ton J. Cleophas, Aeilko H. Zwinderman and Toine F. Cleophas
Ch Chapter 26 Clinical Data where Variability is more Important than Averages
Ton J. Cleophas, Aeilko H. Zwinderman and Toine F. Cleophas
Ch Chapter 27 Testing Reproducibility
Ton J. Cleophas, Aeilko H. Zwinderman and Toine F. Cleophas
Ch Chapter 28 Accuracy of Diagnostic Tests
Ton J. Cleophas, Aeilko H. Zwinderman and Toine F. Cleophas
Ch Chapter 29 Advanced Analysis of Variance
Ton J. Cleophas, Aeilko H. Zwinderman and Toine F. Cleophas
Ch Chapter 3 The Analysis of Safety Data of Drug Trials
Ton J. Cleophas, Aeilko H. Zwinderman and Toine F. Cleophas
Ch Chapter 30 Statistics is No “Bloodless” Algebra
Ton J. Cleophas, Aeilko H. Zwinderman and Toine F. Cleophas
Ch Chapter 31 Bias Due to Conflicts of Interests, some Guidelines
Ton J. Cleophas, Aeilko H. Zwinderman and Toine F. Cleophas
Ch Chapter 4 Equivalence Testing
Ton J. Cleophas, Aeilko H. Zwinderman and Toine F. Cleophas
Ch Chapter 5 Statistical Power and Sample Size
Ton J. Cleophas, Aeilko H. Zwinderman and Toine F. Cleophas
Ch Chapter 6 Interim Analyses
Ton J. Cleophas, Aeilko H. Zwinderman and Toine F. Cleophas
Ch Chapter 7 Multiple Statistical Inferences
Ton J. Cleophas, Aeilko H. Zwinderman and Toine F. Cleophas
Ch Chapter 8 Controlling the Risk of False Positive Clinical Trials
Ton J. Cleophas, Aeilko H. Zwinderman and Toine F. Cleophas
Ch Chapter 9 The Interpretation of the P-Values
Ton J. Cleophas, Aeilko H. Zwinderman and Toine F. Cleophas

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DOI: 10.1007/978-1-4020-4650-6

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