Development and validation of a computational model of the knee joint for the evaluation of surgical treatments for osteoarthritis

R. Mootanah, C.W. Imhauser, F. Reisse, D. Carpanen, R.W. Walker, M.F. Koff, M.W. Lenhoff, S.R. Rozbruch, A.T. Fragomen, Z. Dewan, Y.M. Kirane, K. Cheah, J.K. Dowell and H.J. Hillstrom

Computer Methods in Biomechanics and Biomedical Engineering, 2014, vol. 17, issue 13, 1502-1517

Abstract: A three-dimensional (3D) knee joint computational model was developed and validated to predict knee joint contact forces and pressures for different degrees of malalignment. A 3D computational knee model was created from high-resolution radiological images to emulate passive sagittal rotation (full-extension to 65°-flexion) and weight acceptance. A cadaveric knee mounted on a six-degree-of-freedom robot was subjected to matching boundary and loading conditions. A ligament-tuning process minimised kinematic differences between the robotically loaded cadaver specimen and the finite element (FE) model. The model was validated by measured intra-articular force and pressure measurements. Percent full scale error between FE-predicted and in vitro-measured values in the medial and lateral compartments were 6.67% and 5.94%, respectively, for normalised peak pressure values, and 7.56% and 4.48%, respectively, for normalised force values. The knee model can accurately predict normalised intra-articular pressure and forces for different loading conditions and could be further developed for subject-specific surgical planning.

Date: 2014
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DOI: 10.1080/10255842.2014.899588

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