Validation of numerical flow simulations against phantom measurements in different type B aortic dissection scenarios

Eduardo Soudah, Paula Rudenick, Maurizio Bordone, Bart Bijnens, David García-Dorado, Arturo Evangelista and Eugenio Oñate

Computer Methods in Biomechanics and Biomedical Engineering, 2015, vol. 18, issue 8, 805-815

Abstract: An aortic dissection (AD) is a serious condition defined by the splitting of the arterial wall, thus generating a secondary lumen [the false lumen (FL)]. Its management, treatment and follow-up are clinical challenges due to the progressive aortic dilatation and potentially severe complications during follow-up. It is well known that the direction and rate of dilatation of the artery wall depend on haemodynamic parameters such as the local velocity profiles, intra-luminal pressures and resultant wall stresses. These factors act on the FL and true lumen, triggering remodelling and clinical worsening. In this study, we aimed to validate a computational fluid dynamic (CFD) tool for the haemodynamic characterisation of chronic (type B) ADs. We validated the numerical results, for several dissection geometries, with experimental data obtained from a previous in vitro study performed on idealised dissected physical models. We found a good correlation between CFD simulations and experimental measurements as long as the tear size was large enough so that the effect of the wall compliance was negligible.

Date: 2015
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DOI: 10.1080/10255842.2013.847095

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