Preventative Cancer Treatments Through Optimizing Tissue Structure

Christopher Graser
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Christopher Graser: University of Amsterdam

No 20-012/II, Tinbergen Institute Discussion Papers from Tinbergen Institute

Abstract: The likelihood of cancer emergence is highly dependent on the underlying tissue structure. This article gives evolutionary explanations for why natural selection fails to select for tissue structures that would minimize the likelihood of cancer. In a second step, a mathematical framework is proposed, within which the risk of cancer emergence can be expressed and calculated dependent on a given tissue structure. This can be used to identify optimal structures and strategies for improvement. Lastly, the article explores both, ways to identify target areas for such intervention, as well as avenues towards developing treatment options.

Keywords: Evolution; Evolutionary Game Theory; Cancer (search for similar items in EconPapers)
JEL-codes: C73 I10 Z00 (search for similar items in EconPapers)
Date: 2020-02-22
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Persistent link: https://EconPapers.repec.org/RePEc:tin:wpaper:20200012

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