Science Policy Choices and the Estimation of Cancer Risk Associated with Exposure to TCDD

Michael Gough

Risk Analysis, 1988, vol. 8, issue 3, 337-342

Abstract: United States regulatory agencies use no‐threshold models for estimating carcinogenic risks. Other countries use no‐threshold models for carcinogens that are genotoxic and threshold models for carcinogens that are not genotoxic, such as 2, 3, 7, 8‐tetrachlorodibenzo‐P‐dioxin (TCDD or “dioxin”). The U.S. Environmental Protection Agency has proposed a revision of the carcinogenic potency estimate for TCDD that is based on neither a threshold nor a no‐threshold model; instead, it is a compromise between risk numbers generated by the two irreconcilably different models. This paper discusses the revision and its implications.

Date: 1988
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https://doi.org/10.1111/j.1539-6924.1988.tb00496.x

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Persistent link: https://EconPapers.repec.org/RePEc:wly:riskan:v:8:y:1988:i:3:p:337-342

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