Control of Voltage-Dependent Biomolecules Via Nonequilibrium Kinetic Focusing

Mark M. Millonas and Dante R. Chialvo

Working Papers from Santa Fe Institute

Abstract: We show that voltage-sensitive macromolecules can, by the application of the right type of external voltage fluctuation, be focused with great probability into a desired kinetic substate. As an illustration we consider an eight-state model of the Shaker $K^+$ channel driven by dichotomous voltage fluctuations. This technique may provide a powerful new tool for the study of the kinetics of voltage sensitive ion channels.

Date: 1995-05
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Persistent link: https://EconPapers.repec.org/RePEc:wop:safiwp:95-05-050

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