Anomalous diffusion on dynamical networks: a model for interacting epithelial cell migration

Stefan Thurner, Nikolaus Wick, Rudolf Hanel, Roland Sedivy and Lukas Huber

Physica A: Statistical Mechanics and its Applications, 2003, vol. 320, issue C, 475-484

Abstract: We propose a model for cell migration where epithelial cells are able to detect trajectories of other cells and try to follow them. As cells move along in 2D cell culture, they mark their paths by loosing tiny parts of cytoplasm. Any cell moving on a surface where other cells have moved before faces a network of cell trajectories, which it tries to restrict its motion onto. With the Tsallis modification of classical thermodynamics one can solve the relevant Fokker–Planck like equation and obtain experimentally testable distribution functions. We compare the model to experimental data of normal mammary epithelial cells and cells which have been genetically manipulated to change their cell–cell interaction.

Keywords: Anomalous diffusion; Tsallis distributions; Cell migration (search for similar items in EconPapers)
Date: 2003
References: View complete reference list from CitEc
Citations: View citations in EconPapers (2)

Downloads: (external link)
http://www.sciencedirect.com/science/article/pii/S0378437102015984
Full text for ScienceDirect subscribers only. Journal offers the option of making the article available online on Science direct for a fee of $3,000

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:eee:phsmap:v:320:y:2003:i:c:p:475-484

DOI: 10.1016/S0378-4371(02)01598-4

Access Statistics for this article

Physica A: Statistical Mechanics and its Applications is currently edited by K. A. Dawson, J. O. Indekeu, H.E. Stanley and C. Tsallis

More articles in Physica A: Statistical Mechanics and its Applications from Elsevier
Bibliographic data for series maintained by Catherine Liu ().