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PLOS Digital Health

2022 - 2025

From Public Library of Science
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Volume 1, issue 12, 2022

Optimal mode of delivery in pregnancy: Individualized predictions using national vital statistics data pp. 1-18 Downloads
Karl W Schulz, Kelly Gaither, Corwin Zigler, Tomislav Urban, Justin Drake and Radek Bukowski
Governing partnerships with technology companies as part of the COVID-19 response in Canada: A qualitative case study pp. 1-26 Downloads
Vinyas Harish, Thomas G Samson, Lori Diemert, Ashleigh Tuite, Muhammad Mamdani, Kamran Khan, Anita McGahan, James A Shaw, Sunit Das and Laura C Rosella
Reproducibility of deep learning in digital pathology whole slide image analysis pp. 1-21 Downloads
Christina Fell, Mahnaz Mohammadi, David Morrison, Ognjen Arandjelovic, Peter Caie and David Harris-Birtill

Volume 1, issue 11, 2022

Computational analyses identify addiction help-seeking behaviors on the social networking website Reddit: Insights into online social interactions and addiction support communities pp. 1-15 Downloads
Danny Valdez and Megan S Patterson
Let’s decide what would be convincing, conduct randomized trials with rigorous comparison conditions, and report tests of moderation and publication bias in meta-analyses pp. 1-3 Downloads
Simon B Goldberg, John Torous and Shufang Sun
Telehealth interventions for substance use disorders in low- and- middle income countries: A scoping review pp. 1-18 Downloads
Margaret Isioma Ojeahere, Sarah Kanana Kiburi, Paul Agbo, Rakesh Kumar and Florence Jaguga
Mobile phone–based interventions for mental health show promise of effectiveness, but what does the evidence tell us about what needs to come next? pp. 1-4 Downloads
Nicholas C Jacobson, Patricia Areán and Stephen M Schueller

Volume 1, issue 10, 2022

Effectiveness of tailored digital health interventions for mental health at the workplace: A systematic review of randomised controlled trials pp. 1-25 Downloads
Thirimon Moe-Byrne, Jessie Shepherd, Dorota Merecz-Kot, Marjo Sinokki, Päivi Naumanen, Leona Hakkaart- van Roijen and Christina Van Der Feltz-Cornelis
Population analysis of mortality risk: Predictive models from passive monitors using motion sensors for 100,000 UK Biobank participants pp. 1-22 Downloads
Haowen Zhou, Ruoqing Zhu, Anita Ung and Bruce Schatz
Global healthcare fairness: We should be sharing more, not less, data pp. 1-13 Downloads
Kenneth P Seastedt, Patrick Schwab, Zach O’Brien, Edith Wakida, Karen Herrera, Portia Grace F Marcelo, Louis Agha-Mir-Salim, Xavier Borrat Frigola, Emily Boardman Ndulue, Alvin Marcelo and Leo Anthony Celi
German medical students´ views regarding artificial intelligence in medicine: A cross-sectional survey pp. 1-13 Downloads
Stuart McLennan, Andrea Meyer, Korbinian Schreyer and Alena Buyx
Uncertain imputation for time-series forecasting: Application to COVID-19 daily mortality prediction pp. 1-18 Downloads
Rayane Elimam, Nicolas Sutton-Charani, Stéphane Perrey and Jacky Montmain
Physiologic signatures within six hours of hospitalization identify acute illness phenotypes pp. 1-21 Downloads
Yuanfang Ren, Tyler J Loftus, Yanjun Li, Ziyuan Guan, Matthew M Ruppert, Shounak Datta, Gilbert R Upchurch, Patrick J Tighe, Parisa Rashidi, Benjamin Shickel, Tezcan Ozrazgat-Baslanti and Azra Bihorac

Volume 1, issue 9, 2022

An economic evaluation of an online computer-tailored smoking cessation intervention that includes message frame-tailoring: A randomized controlled trial pp. 1-14 Downloads
Maria B Altendorf, Julia C M van Weert, Ciska Hoving and Eline S Smit
Leveraging mHealth usage logs to inform health worker performance in a Resource-Limited setting: Case example of mUzima use for a chronic disease program in Western Kenya pp. 1-15 Downloads
Simon Savai, Jemimah Kamano, Lawrence Misoi, Peter Wakholi, Md Kamrul Hasan and Martin C Were
Privacy-aware multi-institutional time-to-event studies pp. 1-16 Downloads
Julian Späth, Julian Matschinske, Frederick K Kamanu, Sabina A Murphy, Olga Zolotareva, Mohammad Bakhtiari, Elliott M Antman, Joseph Loscalzo, Alissa Brauneck, Louisa Schmalhorst, Gabriele Buchholtz and Jan Baumbach
Addressing the “elephant in the room” of AI clinical decision support through organisation-level regulation pp. 1-5 Downloads
Joe Zhang, Heather Mattie, Haris Shuaib, Tamishta Hensman, James T Teo and Leo Anthony Celi

Volume 1, issue 8, 2022

Predictability and stability testing to assess clinical decision instrument performance for children after blunt torso trauma pp. 1-16 Downloads
Aaron E Kornblith, Chandan Singh, Gabriel Devlin, Newton Addo, Christian J Streck, James F Holmes, Nathan Kuppermann, Jacqueline Grupp-Phelan, Jeffrey Fineman, Atul J Butte and Bin Yu
Prescription quantity and duration predict progression from acute to chronic opioid use in opioid-naïve Medicaid patients pp. 1-14 Downloads
Drake G Johnson, Vy Thuy Ho, Jennifer M Hah, Keith Humphreys, Ian Carroll, Catherine Curtin, Steven M Asch and Tina Hernandez-Boussard
A proposed de-identification framework for a cohort of children presenting at a health facility in Uganda pp. 1-17 Downloads
Alishah Mawji, Holly Longstaff, Jessica Trawin, Dustin Dunsmuir, Clare Komugisha, Stefanie K Novakowski, Matthew O Wiens, Samuel Akech, Abner Tagoola, Niranjan Kissoon and J Mark Ansermino

Volume 1, issue 7, 2022

Point-of-care motion capture and biomechanical assessment improve clinical utility of dynamic balance testing for lower extremity osteoarthritis pp. 1-17 Downloads
Ryan T Halvorson, Francine T Castillo, Fayyaz Ahamed, Karim Khattab, Aaron Scheffler, Robert P Matthew, Jeffrey Lotz, Thomas P Vail, Brian T Feeley and Jeannie F Bailey
Evaluating criminal justice reform during COVID-19: The need for a novel sentiment analysis package pp. 1-10 Downloads
Divya Ramjee, Louisa H Smith, Anhvinh Doanvo, Marie-Laure Charpignon, Alyssa McNulty-Nebel, Elle Lett, Angel N Desai and Maimuna S Majumder

Volume 1, issue 6, 2022

A novel interpretable machine learning system to generate clinical risk scores: An application for predicting early mortality or unplanned readmission in a retrospective cohort study pp. 1-20 Downloads
Yilin Ning, Siqi Li, Marcus Eng Hock Ong, Feng Xie, Bibhas Chakraborty, Daniel Shu Wei Ting and Nan Liu
Associations between Florida counties’ COVID-19 case and death rates and meaningful use among Medicaid providers: Cross-sectional ecologic study pp. 1-18 Downloads
Katherine Freeman and Judith P Monestime
Predicting resistance to fluoroquinolones among patients with rifampicin-resistant tuberculosis using machine learning methods pp. 1-18 Downloads
Shiying You, Melanie H Chitwood, Kenneth S Gunasekera, Valeriu Crudu, Alexandru Codreanu, Nelly Ciobanu, Jennifer Furin, Ted Cohen, Joshua L Warren and Reza Yaesoubi

Volume 1, issue 5, 2022

A systematic review of federated learning applications for biomedical data pp. 1-14 Downloads
Matthew G Crowson, Dana Moukheiber, Aldo Robles Arévalo, Barbara D Lam, Sreekar Mantena, Aakanksha Rana, Deborah Goss, David W Bates and Leo Anthony Celi
A literature review on the analysis of symptom-based clinical pathways: Time for a different approach? pp. 1-12 Downloads
Nammunikankanange Janak Gunatilleke, Jacques Fleuriot and Atul Anand
General practitioners’ perceptions of using virtual primary care during the COVID-19 pandemic: An international cross-sectional survey study pp. 1-23 Downloads
Edmond Li, Rosy Tsopra, Geronimo Jimenez, Alice Serafini, Gustavo Gusso, Heidrun Lingner, Maria Jose Fernandez, Greg Irving, Davorina Petek, Robert Hoffman, Vanja Lazic, Ensieh Memarian, Tuomas Koskela, Claire Collins, Sandra Milena Espitia, Ana Clavería, Katarzyna Nessler, Braden Gregory O’Neill, Kyle Hoedebecke, Mehmet Ungan, Liliana Laranjo, Saira Ghafur, Gianluca Fontana, Azeem Majeed, Josip Car, Ara Darzi and Ana Luisa Neves
A distributed approach to the regulation of clinical AI pp. 1-8 Downloads
Trishan Panch, Erin Duralde, Heather Mattie, Gopal Kotecha, Leo Anthony Celi, Melanie Wright and Felix Greaves
Feature engineering and machine learning for computer-assisted screening of children with speech disorders pp. 1-18 Downloads
Kerul Suthar, Farnaz Yousefi Zowj, Marisha Speights Atkins and Q Peter He
Clinical time-to-event prediction enhanced by incorporating compatible related outcomes pp. 1-10 Downloads
Yan Gao and Yan Cui

Volume 1, issue 4, 2022

A systematic review of the prediction of hospital length of stay: Towards a unified framework pp. 1-38 Downloads
Kieran Stone, Reyer Zwiggelaar, Phil Jones and Neil Mac Parthaláin
Predicting zip code-level vaccine hesitancy in US Metropolitan Areas using machine learning models on public tweets pp. 1-19 Downloads
Sara Melotte and Mayank Kejriwal
Generalizability challenges of mortality risk prediction models: A retrospective analysis on a multi-center database pp. 1-17 Downloads
Harvineet Singh, Vishwali Mhasawade and Rumi Chunara

Volume 1, issue 3, 2022

Severity and mortality prediction models to triage Indian COVID-19 patients pp. 1-11 Downloads
Samarth Bhatia, Yukti Makhija, Sneha Jayaswal, Shalendra Singh, Prabhat Singh Malik, Sri Krishna Venigalla, Pallavi Gupta, Shreyas N Samaga, Rabi Narayan Hota and Ishaan Gupta
Individual illness dynamics: An analysis of children with sepsis admitted to the pediatric intensive care unit pp. 1-15 Downloads
Sherry L Kausch, Brynne Sullivan, Michael C Spaeder and Jessica Keim-Malpass

Volume 1, issue 2, 2022

The “Ecosystem as a Service (EaaS)” approach to advance clinical artificial intelligence (cAI) pp. 1-8 Downloads
Julian Euma Ishii-Rousseau, Shion Seino, Daniel K Ebner, Maryam Vareth, Ming Jack Po and Leo Anthony Celi
To explain or not to explain?—Artificial intelligence explainability in clinical decision support systems pp. 1-18 Downloads
Julia Amann, Dennis Vetter, Stig Nikolaj Blomberg, Helle Collatz Christensen, Megan Coffee, Sara Gerke, Thomas K Gilbert, Thilo Hagendorff, Sune Holm, Michelle Livne, Andy Spezzatti, Inga Strümke, Roberto V Zicari, Vince Istvan Madai and on behalf of the Z-Inspection Initiative
Transfer learning for non-image data in clinical research: A scoping review pp. 1-22 Downloads
Andreas Ebbehoj, Mette Østergaard Thunbo, Ole Emil Andersen, Michala Vilstrup Glindtvad and Adam Hulman

Volume 1, issue 1, 2022

Applied machine learning for the risk-stratification and clinical decision support of hospitalised patients with dengue in Vietnam pp. 1-13 Downloads
Damien K Ming, Bernard Hernandez, Sorawat Sangkaew, Nguyen Lam Vuong, Phung Khanh Lam, Nguyen Minh Nguyet, Dong Thi Hoai Tam, Dinh The Trung, Nguyen Thi Hanh Tien, Nguyen Minh Tuan, Nguyen Van Vinh Chau, Cao Thi Tam, Ho Quang Chanh, Huynh Trung Trieu, Cameron P Simmons, Bridget Wills, Pantelis Georgiou, Alison H Holmes, Sophie Yacoub and on behalf of the Vietnam ICU Translational Applications Laboratory (VITAL) Investigators
Best practices in the real-world data life cycle pp. 1-14 Downloads
Joe Zhang, Joshua Symons, Paul Agapow, James T Teo, Claire A Paxton, Jordan Abdi, Heather Mattie, Charlie Davie, Aracelis Z Torres, Amos Folarin, Harpreet Sood, Leo A Celi, John Halamka, Sara Eapen and Sanjay Budhdeo
PLOS Digital Health, a new journal driving transformation in the delivery of equitable and unbiased healthcare pp. 1-2 Downloads
Leo Anthony Celi
Regulatory-approved deep learning/machine learning-based medical devices in Japan as of 2020: A systematic review pp. 1-12 Downloads
Nao Aisu, Masahiro Miyake, Kohei Takeshita, Masato Akiyama, Ryo Kawasaki, Kenji Kashiwagi, Taiji Sakamoto, Tetsuro Oshika and Akitaka Tsujikawa
Mobile phone-based interventions for mental health: A systematic meta-review of 14 meta-analyses of randomized controlled trials pp. 1-21 Downloads
Simon B Goldberg, Sin U Lam, Otto Simonsson, John Torous and Shufang Sun
Open challenges in developing digital therapeutics in the United States pp. 1-4 Downloads
Brenda Y Miao, Douglas Arneson, Michelle Wang and Atul J Butte
Making data for good better pp. 1-4 Downloads
Caroline Buckee, Satchit Balsari and Andrew Schroeder
Ideal algorithms in healthcare: Explainable, dynamic, precise, autonomous, fair, and reproducible pp. 1-16 Downloads
Tyler J Loftus, Patrick J Tighe, Tezcan Ozrazgat-Baslanti, John P Davis, Matthew M Ruppert, Yuanfang Ren, Benjamin Shickel, Rishikesan Kamaleswaran, William R Hogan, J Randall Moorman, Gilbert R Upchurch, Parisa Rashidi and Azra Bihorac
Page updated 2025-05-31