PLOS Digital Health

2022 - 2026

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Volume 5, issue 10, 2026

When the algorithm passes the test but fails the patient pp. 1-4

Alex Mirugwe

The world’s oldest living culture leads the way with interpretable generative AI: Aboriginal women shaping the future of perinatal mental health services pp. 1-23

Guanjin Wang, Hachem Bennamoun, Wai Hang Kwok, Rehan Raza, Ferdous Sohel, Bridgette Kelly, Trish Ratajczak, Corinne Reid, Rhonda Marriott, Roz Walker, Jayne Kotz and Tracy Reibel

Impacts of digital third-wave interventions for adults on wellbeing and mental health outcomes: A systematic review and meta-analysis of randomized controlled trials pp. 1-23

Tom C Gordon, Andrew H Kemp, Josh Hope-Bell and Darren J Edwards

Demographic subgroup-aware analysis of blood pressure predictive models pp. 1-18

Blessing Kolawole, Sinuo Fan, Yingjie Lao and Valencia J Koomson

A machine learning model for in-hospital mortality prediction in patients with sepsis-related myocardial injury pp. 1-21

Da-cheng Wang, Yan-pin Liu, Yu-ting Wang, Xiao-huan Zhuang, Xiao-peng Yin, Xin-yuan Zhang and Yan Zhuang

STREAM: A data-driven framework for physiological state monitoring in ICU patients pp. 1-22

Ali Namvar, Sundaresh Ram, Wassim W Labaki, Stefanie Galban, Njira L Lugogo and Craig J Galban

Recommendations for the analysis of leading indicators in epidemic surveillance pp. 1-22

Jonathon Mellor, Maria Tang, Robert S Paton and Thomas Ward

Co-developing Georgia’s National Digital Health Strategy through a multistakeholder convergence workshop: An implementation case study from the WHO European Region pp. 1-28

Nato Gzirishili, Mehar Grover, Resham Sethi, Mariam Beridze, Tomas Roubal, Lela Sulaberidze, Karapet Davtyan, Silviu Domente and Karthik Adapa

Toward predictive prosthetic socket modeling: Preliminary linear regression models of transradial limb–socket geometry pp. 1-19

Vishal Pendse, Nader Allam, Calvin C Ngan, Elaine Lorette, Isabelle Morin-Girard and Jan Andrysek

Evaluating an LLM-assisted workflow for clinical documentation: A pilot randomized controlled trial on time and quality pp. 1-17

Tomohiro Takayama, Keina Sado, Kenji Suda, Hiroshi Tamura, Naoko Ueda-Arakawa, Kenji Ishihara, Yuta Ueda, Kazuya Okamoto, Luciano Henrique de Oliveira Santos, Tetsuro Oshika, Tomohiro Kuroda, Akitaka Tsujikawa and Masahiro Miyake

Regulating the drafting fiction: A qualitative content analysis of official guidance and regulator documents on AI scribe adoption and use in healthcare pp. 1-24

Samuel Oluwatobi Atiku

Changes in the acceptance of artificial intelligence in medicine among physicians and the general public in Japan: A repeated cross-sectional comparison of 2018 and 2025 pp. 1-14

Teppei Suzuki, Honoka Tamori, Kazuki Ohashi, Yasuhiro Morii, Kenji Hirata, Kohsuke Kudo and Katsuhiko Ogasawara

Transparency, accountability, and scholarly integrity: A systematic narrative review of artificial intelligence governance frameworks in healthcare publication pp. 1-14

Amina Silva, Bruna Canever, Monica Lino and Vanessa Silva e Silva

Refocusing algorithmic fairness on feature-level bias: A diagnostic approach using dutch EHR data pp. 1-20

Cathleen S Parsons, Shelley-Ann M Girwar, Sepinoud Azimi, Marco R Spruit and Marcel R Haas

Contribution of artificial intelligence research to the development of inclusive applications for people with disabilities: A scoping review (2015–2025) pp. 1-20

Soutongnoma Safiata Kaboré, Azadeh Bayani, Léandre Parfait Epoh Ewane, Davllyn Santos Oliveira dos Anjos, Jean Noel Nikiéma and Muriel Mac-Seing

Volume 5, issue 9, 2026

Comparative predictive modeling of pediatric spirometry reference equations in Jordanian children: Complex versus simple models pp. 1-22

Walid Al-Qerem, Anan Jarab, Judith Eberhardt, Khalda Smairan, Yousef Mimi and Maher Khdour

Data distribution impacts the performance and generalisability of contrastive learning-based foundation models of electrocardiograms pp. 1-21

Gul Rukh Khattak, Konstantinos Patlatzoglou, Joseph Barker, Libor Pastika, Boroumand Zeidaabadi, Aidan R Birdi, Jiayu Huo, Ahmed El-Medany, Hesham Aggour, Yixiu Liang, Antonio H Ribeiro, Jeffrey Annis, Antonio Luiz Pinho Ribeiro, Junbo Ge, Daniel B Kramer, Jonathan W Waks, Evan Brittain, Nicholas Peters, Fu Siong Ng and Arunashis Sau

Tailoring in eHealth lifestyle interventions targeting people with cardiometabolic conditions and lower socioeconomic position: A scoping review pp. 1-31

Sandra Van Mellaert, Martha S Kreuzberg, Iris ten Klooster, Bert-Jan F van Beijnum, Jan N van Rijn and Monique Tabak

Independent evaluation of machine learning and deep learning models for breast cancer detection pp. 1-23

Deepthi, Ashalatha Nayak and Rani Oomman Panicker

Implementation of an opioid use disorder (OUD) machine-learning phenotype in real-time for the ADAPT clinical trial pp. 1-18

Huan Li, Mark Iscoe, John Lutz, Carolina Diniz Hopper, Sabrina Fried, Josue Minaya, Caroline Raymond King, Olga Reykhart, Hyung Paek, Daniella Meeker, Edward R Melnick and R Andrew Taylor

Augmenting patient safety surveillance in radiation oncology with large language model-based root cause analysis: A proof-of-concept study pp. 1-18

Yuntao Wang, Mariluz De Ornelas, Matthew T Studenski, Elizabeth Bossart, Siamak P Nejad-Davarani and Yunze Yang

Early malaria risk screening in Nigerian minors using AutoML and cluster-based analysis of non-clinical survey data pp. 1-33

Ashiqur Rahman Khan, Nafisa Mahbub, Ridwan Al Aziz, Mahamudul Hassan Siddique and Zahidul Islam Sayeem

The economics of accuracy for medical reasoning with large language models pp. 1-35

Kiran Bhattacharyya and Sreeram Kamabattula

Socioeconomic determinants of malaria in Ugandan children: An interpretable machine learning approach for public health policy pp. 1-14

Cleiane Gonçalves Oliveira, Marcos Flávio S V D’Angelo, Matheus P Libório, Marcelo Perim Baldo and Hasheem Mannan

A feasibility study evaluating seismocardiography for the detection of heart failure pp. 1-14

Ahmad Agam, Emil Korsgaard, Troels Yding Haugstrup, Kasper Janus Grønn Emerek, Maria Weinkouff Pedersen, Massar Omar, Jacob Eifer Møller, Kristian Kragholm, Samuel Emil Schmidt and Peter Søgaard

Utilization of a HIPAA-compliant large language model chatbot in an academic pediatric medical center pp. 1-10

Benjamin Rader, Dinesh K Rai, Melissa L Stewart, Sarah Lejfer, Sampath Chennuri, James Hartwell, Victor Moyano, Max H Witwer, Peter C Laussen, Heather L Nelson and John S Brownstein

Deep learning for blood glucose prediction: Reproducibility challenges and factors affecting differential performance pp. 1-19

Baiying Lu, Biratal Wagle, Zhaohui Liang, Yanjun Cui and Temiloluwa Prioleau

Impact of mobile health interventions for mental health literacy: A systematic review and meta-analysis of randomized controlled trials pp. 1-19

Jamin Patel, Sheriff Ibrahim and Tarun Reddy Katapally

Development and external evaluation of an interpretable machine-learning model for early prediction of organ failure in higher-risk acute pancreatitis patients: A multicentre cohort study pp. 1-19

Di Wu, Wenhao Cai, Chunmei Chen, Minting Chen, Yang Lv, Yilin Huang, Anthony Evans, Juan Lin, Diane Latawiec, Arjun Kattakayam, Rajarshi Mukherjee, Wei Huang, Qing Xia, Jie Xiao, Chunqiu Su, Jie Peng, Kuirong Jiang and Robert Sutton

Explainable machine learning for breast cancer prediction in resource-constrained settings: A multi-algorithmic framework integrating shap-based transparency with clinical decision support pp. 1-17

Oluwaseun Adebayo Bamodu, Sumaiya Nezam and Chen-Chih Chung

Volume 5, issue 8, 2026

Effectiveness of nonclinic-based dual-task training on physical and cognitive functions and activities of daily living in older adults with cognitive decline: A systematic review and meta-analysis pp. 1-25

Jeerati Rattanatreyanupab, Htet Htet Hnin, Theerapol Witthiwej, Vimonwan Hiengkaew, Pagamas Piriyaprasarth, Yasutaka Nikaido, Ammarin Thakkinstian, Kunlawat Thadanipon, Saharat Liampeng and Sunee Bovonsunthonchai

Prediction tools to prioritise hospitalised adult patients at risk of drug related problems: An umbrella review pp. 1-25

Daria S Gutteridge, Dona Babu, Jacquelina Stasinopoulos, Annabel Calder, Michael Bakker, Sally Marotti, Bronwin Patrickson, Karen Macolino, Craig Martin, Lijun Zhao, Niranjan Bidargaddi and Janet K Sluggett

To learn or not to learn? Model-based estimation of motor learning in a large, “in the wild”, home rehabilitation database pp. 1-22

Yan Wen, Dongze Ye, Rukshana Poudel, Dan Zondervan, David Reinkensmeyer and Nicolas Schweighofer

HEART-Watch: A multimodal physiological dataset from a Google Pixel Watch across different physical states pp. 1-22

Jathushan Kaetheeswaran, Boyi Ma, Ali Abedi, Shehroz S Khan and Milad Lankarany

AI alignment in medical imaging: Unveiling hidden biases through counterfactual analysis pp. 1-21

Haroui Ma, Francesco Quinzan, Theresa Willem and Stefan Bauer

AI-driven dual-task prediction model for co-stratifying efficacy and toxicity in NSCLC immunotherapy pp. 1-20

Hanlin Ding, Yuting Ren, Siqi Ding, Yuzhong Chen, Yuemin Wu, Yipeng Feng, Wenjie Xia, Xuming Song, Rutao Li, Qixing Mao, Bing Chen, Hui Wang, Bin Zhu, Anpeng Wang, Lin Xu, Yan Qiang, Gaochao Dong and Feng Jiang

Assessing the informative value of macroeconomic indicators for public health forecasting pp. 1-20

Shome Chakraborty, Fardil Khan and Soutik Ghosal

Clinical predictive artificial intelligence evaluation: A narrative review of trial designs and practical considerations pp. 1-20

Maxime Fosset, Joris Pensier, Boris Jung, Arjumand Siddiqi, Muhammad Mamdani and Leo Anthony Celi

Expiratory time constant patterns reveal obstructive lung mechanics in non-obstructive spirometry pp. 1-17

Filip Depta, Surya P Bhatt, Manuel Heinz, Radek Černý, Vladimír Koblížek and Pavol Pobeha

Knowledge graph-guided multiple sclerosis identification and therapeutic trend analysis: Real-world evidence from two large healthcare systems pp. 1-15

Ziming Gan, Wen Zhu, Weijing Tang, Sara Morini Sweet, Michele Morris, Yunqing Han, Chenyi Chen, Junwei Lu, Emily Song, Mohammed Moro, Shyam Visweswaran, Tianrun Cai, Tanuja Chitnis, Tianxi Cai and Zongqi Xia

ITHindex: An integrated web-based platform for intratumor heterogeneity evaluation pp. 1-15

Yutao Liu, Yuan Jiang, Wenchuan Xie, Feidie Duan, Shuiting Fu, Jing Zhao, Jinyu Yang, Jianchun Duan, Guoqiang Wang, Yuzi Zhang, Shangli Cai and Yongqin Wen

Social factors associated with the development of e-health literacy: A mixed-methods study among patient organization members and representatives pp. 1-18

Lea Wiedemann, Jan Hinrichsen, Jonas Lander, Simon Wallraf, Marie-Luise Dierks, Henk Jasper van Gils-Schmidt and Sabine Wöhlke

CAMI-DM: Development and validation of a multi-algorithm model for in-hospital mortality risk prediction in diabetic patients with acute myocardial infarction — The China acute myocardial infarction registry pp. 1-23

Zuoxiang Wang, Zheng Yin, Junxing Lv, Sheng Zhao, Zhengqing Ba, Jingang Yang, Haiyan Xu, Xiaojin Gao, Yongjian Wu and Yuejin Yang

Machine learning-based quantitative structure–activity relationship model for antibiotic prediction and discovery pp. 1-16

Jiratchaya Nakbang, Chonthicha Arbsuwan, Santitham Prom-on and Peerut Chienwichai

Inclusive mobile brain-body imaging achieves equivalent EEG data quality across racial groups pp. 1-16

Sodiq Fakorede, Ke Liao, KathleenMae Rogers, Kai Cheng, Lydia Pemberton, Laura E Martin and Hannes Devos

A natural language processing approach to determine whether streamlined health technology assessment for multi-indication medicines is feasible pp. 1-16

Isaiah Luc, Drew Carter, Erik Bergman, Gabriel Westman and Tracy Merlin

Volume 5, issue 7, 2026

User engagement in the tuberculosis treatment support tools intervention and its impact on treatment outcomes: A secondary analysis of a pragmatic trial pp. 1-16

Sarah J Iribarren, Jason Rupp, Jennifer Sprecher, Barry Lutz and Fernando Rubinstein

Artificial intelligence–based chatbots to enhance medication adherence among patients with non-communicable chronic diseases: Systematic review and meta-analysis pp. 1-16

Siyu Chen, Yuan Fang, Liwen Ding, Phoenix K H Mo and Zixin Wang

An exploratory mixed-methods assessment of private health sector readiness for reporting through the Ministry of Health and Child Care Health Information System in Zimbabwe pp. 1-16

Memory Chimsimbe, Tariro C Mando, Munyaradzi Murwira, Juliet G Nyamasve, Eliud Wekesa, Anne Njeri, Patron Mafaune, Jennifer Harris Requejo, Manes Munyanyi, Winston Chirombe, Simukai T Zizhou, Oona Campell and Richard Makurumidze

Beyond technology usefulness: Health system reliability, and socio-demographic and professional factors as shapers of technostress in physicians pp. 1-24

Pilar Ficapal-Cusí, Joan Torrent-Sellens and Oriol Yuguero Torres

Time-series prediction of adverse birth outcomes in the U.S. using multilayer perceptron neural networks pp. 1-17

Bayuh Asmamaw Hailu

Identifying dissemination strategies for promoting adoption of digital health interventions in clinical settings: A convergent parallel study on text message support for HIV pre-exposure prophylaxis (PrEP) adherence pp. 1-19

Erik M S Ocean, Sonal D Sharma and Tyler B Wray

Multi-scenario evaluation of federated learning for privacy-preserving malaria prediction with Ghana DHS data pp. 1-19

Daniel Kwasi Kovor and Eric Opoku Osei

Internet use for pregnancy-related information and its correlates among women attending antenatal care in Mogadishu, Somalia pp. 1-19

Mohamed Mustaf Ahmed, Luul Mohamed Ibrahim, Roodo Abdullahi Elmi, Zhinya Kawa Othman, Francesco Branda, Olalekan John Okesanya, Uthman Okikiola Adebayo, Shuaibu Saidu Musa, Abdullahi Hassan Elmi, Abdirasak Sharif Ali and Don Eliseo Lucero-Prisno

Design and development of a disease-agnostic remote patient monitoring typology and associated tools pp. 1-15

Ibukun-Oluwa Omolade Abejirinde, Vanessa Kishimoto, Janette Brual, Kaylen J Pfisterer, Nishath Uddin, Taylor Pratt, Cathleen Fleury, Azza Osman and Onil Bhattacharyya

Quantitative analysis of handwriting kinematics in primary and lower secondary school children through a sensorized ink pen: A cross-sectional population-based study pp. 1-26

Simone Toffoli, Linda Greta Dui, Stefania Fontolan, Francesca Lunardini, Milad Malavolti, Chiara Piazzalunga, Alice Donati, Cesare Cornoldi, Cristiano Termine and Simona Ferrante

Digital phenotyping of CGM engagement reveals distinct glycemic outcomes pp. 1-20

Bowen Zhang, Tomoki Okuno, Emma Li, Ethan Riggins, Evie L Shen, Joleen Vansomphone, Estelle M Everett, Gregory J Norman, Donald R Miller, Peter D Reaven, Hua Zhou and Jin J Zhou

Large language models as versatile predictive engines for notifiable infectious diseases pp. 1-20

Xinsheng Wu, Jinyuan Wu, Zhongwen Wang, Xinyue Feng, Ye Yao, Jason J Ong and Huachun Zou

Toward universal representations of the living: Physiological invariance for transportable medical AI pp. 1-27

Alexandre Vallée

Doctors vs. Algorithms: Physicians, too, struggle to learn from evidence that contradicts AI suggestions pp. 1-14

Aranzazu Vinas, Fernando Blanco and Helena Matute

MERWACS: Development and external validation of a non-invasive machine learning tool for identifying subjects to be screened for CKD pp. 1-25

Daniel Yoo, Vy Kim Nguyen, Umberto Maggiore and Olivier Jolliet

On the road to fully automated insulin delivery: A systematic review of meal announcement free algorithms pp. 1-29

Muhammad Ibrahim, Aleix Beneyto, Ivan Contreras and Josep Vehi

Large language models enable prognostic stratification of cancer patients using real-world clinical notes pp. 1-18

Niklas Kiermeyer, Tim Lenfers, Amin Dada, Julian Friedrich, Sameh Khattab, Eric Knop, Jan Egger, Markus Pauly, Andreas Jung, Grégoire Montavon, Jens T Siveke, Marcel Wiesweg, Stefan Kasper, Ulf P Neumann, Frederick Klauschen, Sylvia Hartmann, Martin Schuler, Philipp Keyl, Jens Kleesiek and Julius Keyl

Health equity and public acceptance of large language models in healthcare in China: A national population-based survey pp. 1-18

Jiaying Li, Helen Yue Lai Chan, Zengjie Ye, Xiang Qi, Wai Tong Chien and Ka Ming Chow

Evaluating the quality of tabular synthetic data in health care pp. 1-23

Ivana Nanevski, Maryam Mohebi, Sebastian Jäger, Karen Otte, Fabian Prasser, Matthias Schulte-Althoff, Daniel Fürstenau and Felix Biessmann

Healthcare unplugged: Disparities in broadband internet and health facility access among US counties pp. 1-11

Khushi Kohli, Stephanie Wang, Cody Chou, Bhav Jain, Kavya M Shah, Mahi Kohli, Edward C Dee and Sandeep Palakodeti

Adaptive multimodal fusion via Gated Parallel Mamba architecture for ultra-high-precision stroke lesion segmentation in medical imaging pp. 1-22

Runnan He, Leshui Dong, Shuang Xia, Chen Cao, Youwei Wang, Meijun Pang, Kuo Zhang, Xiuyun Liu, Dong Ming and Mark Haacke

Development, internal and external evaluation of an artificial intelligence algorithm for child growth monitoring in primary care pp. 1-22

Pauline Scherdel, Raphaële Houlbracq, Emmanuel Lecoeur, Juliane Léger, Raja Brauner, Jérémie F Cohen, V Study Group Ebgm, Martin Chalumeau and Barbara Heude

Modeling predictors of incomplete antenatal care utilization among reproductive-age women in Ethiopia using machine learning algorithms and SHAP interpretation pp. 1-1

Jibril Bashir Adem, Anas Ali Alhur, Abdene Weya Kaso, Meron Asmamaw Alemayehu, Shimels Derso Kebede, Agmasie Damtew Walle, Daniel Niguse Mamo and Ermias Bekele Enyew

A digital marker for stratifying cardiovascular metabolic comorbidities among the middle-aged and elderly adults pp. 1-1

Danhui Mao, Sheng Zhao and Jiao Lu

Test-fairness deep learning with influence score pp. 1-21

Jacky Chung-Hao Wu, Chang-Yu Shih, Nien-Chen Wu, Wei-Wen Chen, Henry Horng-Shing Lu and Shaw-Hwa Lo

Volume 5, issue 6, 2026

A global analysis of national cardiovascular disease control plans using a multi-agent artificial intelligence model pp. 1-100

Hugh Pearson, Caleb J Kumar, Che L Reddy, Estella Rose LeBlanc, Rifat Atun and With the CVD Control Collaborative

Digital innovations and health information systems: Lessons learned from implementing ALMANACH in Nigeria pp. 1-18

Andrea Bernasconi, Daniel Ishaya, Ibrahim Sahabo, Muazu Muazu and Marianne van der Sande

A scoping review of barriers and facilitators to implementing tele-mental health solutions for rural, remote and underserved populations in low- and middle-income countries pp. 1-23

Sandra Jumbe, Aysha Groen, Lisa Ballard, Alexander Torbuck, Deniz Naghibi, Sophie Leijdesdorff, Jose G Perez-Ramos, David Lim, Virender Sorout, Dingaane Msowoya, Winnie W S Mak, Rodrigo Ramalho and Bessie Malila

Who gets included? Equity in digital and decentralised mental health and neurodevelopmental trials: A systematic review pp. 1-24

Sophie S Hall, Charlotte L Hall, Christopher Partlett, Alexia Jeayes, Nikita Rattu, Helen Henshaw, Jennifer Martin and Emily Shoesmith

A fairness framework for natural language processing in substance use disorders and overdose pp. 1-4

David T Zhu, Suhanee Mitragotri and Suzanne Tamang

A digital twin approach for simultaneous reconstruction of brain anatomy and dynamics from neural data pp. 1-26

Michelangelo Fabbrizzi, Lorenzo Gaetano Amato, Leonardo Martinelli, Jacopo Carpaneto, Emanuele Bartolini, Sara Calderoni, Alessandra Retico, Alberto Arturo Vergani and Alberto Mazzoni

Volume 5, issue 5, 2026

Optimization of artificial intelligence models for prediction of new-onset cardiovascular disease in patients with arterial hypertension pp. 1-18

Enrique Rodilla, Olast Arrizibita-Iriarte, Blanca Miranda-Serrano, Luis-Miguel Ruilope-Urioste, Germán Sedano-Gil, Alberto Ortiz, José-Antonio Costa-Muñoz, José Chordá-Ribelles, Maialen Zabalza-Zudaire and Onintza Sayar-Beristain

Video-based detection of Delirium in hospitalized adults pp. 1-18

Maanasa Mendu, Ryan A Tesh, Kyle Pellerin, Grace E Steward, Ivo H Cerda, Marta Williams, Mia Colman, Simran Shah, Alice D Lam, Sydney S Cash, M Brandon Westover and Eyal Y Kimchi

What can shopping transactional data reveal about relative prevalence of menstrual pain and period poverty in England? pp. 1-16

Victoria Sivill, Vanja Ljevar, James Goulding and Anya Skatova

Multidimensional evaluation of large language models on the AAP in-service examination: Assessing accuracy, calibration, and citation reliability pp. 1-19

Prita Abhay Dhaimade and Robin Henderson

Dengue hospitalizations in Brazil: Forecasting with climatic and physicians’ digital search data under real-world reporting delays pp. 1-19

Dayanna Quintanilha Palmer, Marcela Motta, Eduardo Moura, Danielly Xavier, Guilherme Schittine, Angélica Caseri and Ronaldo Gismondi

Deep-learning time-series anomaly detection of acute kidney injury from creatinine–eGFR trajectories in the ICU pp. 1-19

Yoonjin Kang, Soojeong Yun, Seung Min Song, Ji Eun Kim, Hyo Jin Kim, Eun Jung Cho, Shin Young Ahn, Young Joo Kwon and Min Woo Kang

Engaging individuals in digital health research panels: A qualitative study including participants in vulnerable positions pp. 1-19

Corine Oldhoff-Nuijsink, Mirjam P Fransen, Jeanine Suurmond, Linda WP Peute and Marloes E Derksen

Moving beyond the benchmarks: Five foundational principles for meaningful AI evaluation in healthcare pp. 1-13

Catherine G Bielick, Aya Awwad, Jacob Ellen, Laleh Jalilian, Liam G McCoy, Vishala Mishra, Esli Osmanlliu, Stephen R Pfohl and Leo A Celi

Identifying factors associated with vaping cessation in young adults: A machine learning and XAI approach pp. 1-1

Poolakkad S Satheeshkumar, Ian Lango, Swarnali Zafo, Mikaiel Ebanks, Rahul Kumar Das, Kit Wai Cheung, Roberto Pili and Supriya D Mahajan

Early identification of high-risk individuals for mortality after lung transplantation: A retrospective cohort study with topological feature engineering pp. 1-29

Alexy Tran-Dinh, Enora Atchade, Sébastien Tanaka, Brice Lortat-Jacob, Yves Castier, Hervé Mal, Jonathan Messika, Pierre Mordant, Philippe Montravers and Ian Morilla

Volume 5, issue 4, 2026

Sharing digital health data responsibly: Balancing open science with participant privacy pp. 1-5

Camille Nebeker, Shahin Samiei and Santosh Kumar

Artificial intelligence for research capacity strengthening: Two reviews and a pathway to shift power in global health pp. 1-14

Brian Wahl, Tiffany Nassiri-Ansari, Daniel D Redpath, Pascale Allotey and Nina Schwalbe

Reliability of a convolutional neural network in segmenting multiple sclerosis lesions from MRI: Impact of data augmentation, image modality and tolerance with U-Net architecture pp. 1-25

Adam C Szekely-Kohn, Marco Castellani, Luca Baronti, Zubair Ahmed, William G K Manifold, Michael Douglas and Daniel M Espino

An effective deep learning algorithm for medical image registration pp. 1-22

Jinqiu Deng, Ke Chen, Mingke Li, Zhichao Zuo, Alejandro F Frangi and Jianping Zhang

Machine Learning-Based Pattern Recognition of Risk Factors for Low Back Pain among Adolescent Cricket Players in Dhaka City pp. 1-1

Marzana Afrooj Ria, Tasrima Trisha Ratna, Shudeshna Chakraborttye Purba, Rubal Kar, Mohoshina Karim, Md Osman Ali, Erfat Jaren Chaity, Shahadath Hossen, Joynal Abedin Imran and Shahriar Hasan

A pilot study of the online Acceptance and Commitment Therapy Guide for Immigrant Resilience: A culturally adapted intervention for undocumented community members pp. 1-20

José Manuel González Vera, Melanie M Domenech Rodríguez, Alejandro L Vázquez, Korena S Klimczak, Miriam Mukasa, Guadalupe Gabriel San Miguel, Damilola Daramola, Jenifer García Mendoza and Michael E Levin

Use of generative AI for health among urban youth in Pakistan: A mixed-methods study pp. 1-20

Ahsan Mashhood, Aamna Ahmed, Inaya Khan, Maryam Hashim and Sara Baloch

Leveraging deep learning to infer continuous predictions from ordinal labels in medical imaging pp. 1-17

Katharina V Hoebel, Andréanne Lemay, John Peter Campbell, Susan Ostmo, Michael F Chiang, Christopher P Bridge, Matthew D Li, Praveer Singh, Aaron S Coyner and Jayashree Kalpathy-Cramer

Equiflow: An open-source software package for evaluating changes in cohort composition pp. 1-15

Jacob Gould Ellen, Chrystinne Fernandes, Martin Viola, Keagan Yap, Arinda Jordan, Mutesi Flavia Kirabo, João Matos, Pedro Moreira and Leo Anthony Celi

Telemedicine adoption in cardiology: Determinants and predictors identified using Bayesian Model Averaging and Machine Learning pp. 1-18

Pascal Petit, Jonathan Nübel, Marie Josephine Walter, Christian Butter, Martin Heinze, Yuriy Ignatyev, Anja Haase-Fielitz, Nicolas Vuillerme and Felix Muehlensiepen

Volume 5, issue 3, 2026

Vascular age estimation using a consumer wearable sleep tracker pp. 1-20

Gizem Yilmaz, Shohreh Ghorbani, Ju Lynn Ong, Hosein Aghayan Golkashani, Chen Zhang, B T Thomas Yeo and Michael W L Chee

3D-ViT-UNet: 3D Vision transformer based Unet-like model for Volumetric Brain Tumor Segmentation pp. 1-27

Sikandar Afridi, Atif Jan, Muhammad Abeer Irfan, Muhammad Irfan Khattak and Taimur Ahmed Khan

The adaptive large language models for vaccine prediction: A novel approach to vaccine demand prediction with engineered deviation prompts pp. 1-14

Mingming Chen, Qiangsong Wu, Zilong Wang, Qi Qi, Yi Hu and Tenglong Li

A problem of Epic proportion pp. 1-16

Rawan Abulibdeh, Matthew G Crowson, Molly J Douglas, Mena Ramos, Noelle N Saillant and Leo Anthony Celi

Heterogeneous associations of a mobile health-based disease management program on uncontrolled hypertension: A target trial emulation study pp. 1-16

Masashi Kanai, Takahiro Miki, Takuya Toda, Yuta Hagiwara and Takaaki Ikeda

Interpretable machine learning for predicting delays in seeking abortion among reproductive-aged women in Ethiopia: A study using EDHS 2016 data pp. 1-19

Meron Asmamaw Alemayehu, Almaw Genet Yeshiwas, Abebaw Molla Kebede, Habitamu Mekonen, Getaneh Atikilt Yemata, Amare Genetu Ejigu, Ahmed Fentaw Ahmed, Abathun Temesgen, Gashaw Melkie Bayeh, Chalachew Yenew, Rahel Mulatie Anteneh, Zeamanuel Anteneh Yigzaw, Fantu Mamo Aragaw, Getasew Yirdaw, Sintayehu Simie Tsega, Anley Shiferaw Enawgaw, Tilahun Degu Tsega, Zufan Alamrie Asmare and Berhanu Abebaw Mekonnen

SynthCraft: An AI partner for synthetic data generation to support data access and augmentation in healthcare pp. 1-15

Thomas Callender, Anders Boyd, Robert Davis, Silas Ruhrberg Estevez, Juan M Lavista Ferres and Mihaela van der Schaar

Impact of electronic health records on nursing workflow efficiency and predictive factors in Palestinian hospitals pp. 1-13

Fuad Farajalla, Mousa Farajallah, Nesreen Alqaissi, Mohammad Qtait and Zeenat Mousa Mesk

Clustering of disease trajectories with explainable machine learning: A case study on postoperative delirium phenotypes pp. 1-21

Xiaochen Zheng, Ahmed Allam, Manuel Schürch, Xingyu Chen, Maria Angeliki Komninou, Reto Schüpbach, Jan Bartussek and Michael Krauthammer

Performance of predictive AI-based clinical decision support systems across clinical domains: A systematic review and meta-analysis pp. 1-31

William J Waldock, Ahmad Guni, Ara Darzi and Hutan Ashrafian

Autism data sharing: Benefits, challenges, and recommendations pp. 1-18

Alexandra Lautarescu, Brett Trost, Azadeh Kushki, Bethany Oakley, Síofra Heraty, David Belton, Alison Boyle, Sarah Douglas, Ciara J Molloy, Rosemary Holt, Madeleine Bloomfield, Florence Campana, Miro Cupak, Erica Stevenson, Julian Tillmann, Christopher Chatham, Evdokia Anagnostou, Dean Hartley and Tony Charman

Advancing the science of qualitative patient preference assessment using large language models pp. 1-18

Ted Grover, Emanuel Krebs, Deirdre Weymann, Morgan Ehman and Dean A Regier

Participatory-informed preference optimization (PiPrO): A reinforcement learning simulation study pp. 1-18

Tara Templin, Shuyi Song, Sophia Fort and Nasa Sinnott-Armstrong

Cardiology knowledge assessment of retrieval-augmented open versus proprietary large language models pp. 1-11

Constantine Tarabanis, Shaan Khurshid, Areti Karamanou, Rodo Piperaki, Lucas A Mavromatis, Aris Hatzimemos, Dimitrios Tachmatzidis, Constantinos Bakogiannis, Vassilios Vassilikos, Patrick T Ellinor, Lior Jankelson and Evangelos Kalampokis

Volume 5, issue 2, 2026

Early individualized risk prediction using clinical data for children during the febrile phase of dengue in outpatient settings in Vietnam and Thailand pp. 1-16

Sorawat Sangkaew, Bethan Cracknell Daniels, Damien K Ming, Bernard Hernandez, Pau Herrero, Piyarat Suntarattiwong, Siripen Kalayanarooj, Anon Srikiatkhachorn, Alan L Rothman, Darunee Buddhari, Nguyen Lam Vuong, Phung Khanh Lam, Minh Tuan Nguyen, Bridget Wills, Cameron Simmons, Christl A Donnelly, Sophie Yacoub, Alison Holmes and Ilaria Dorigatti

First-line risk stratification with machine learning models facilitates rapid triage for non-ST-elevation myocardial infarction pp. 1-16

Wei-Jia Luo, Yih-Mei Liou, Cheng-Han Hsiao, Chi-Sheng Hung, Heng-Yu Pan, Chien-Hua Huang, Pan-Chyr Yang and Kang-Yi Su

Optimizing vedolizumab therapy in ulcerative colitis: A critical synthesis of trial evidence and the emerging role of artificial intelligence pp. 1-8

Alfadl Abdulfattah

Topologically distinct 2D and 3D intratumoral heterogeneity scores for preoperatively predicting invasiveness in stage I lung adenocarcinoma: A multicenter study pp. 1-19

Zhichao Zuo, Xiaohong Fan, Ying Zeng, Wanyin Qi, Wen Liu, Wei Li and Qi Liang

Mixed-methods assessment of engagement with a digital intervention: The Wrapped feasibility randomised controlled trial pp. 1-17

Lauren Schumacher, Kayleigh Kwah, Rebecca Gill, Rik Crutzen, Katherine Brown, Stephen Bremner, Louise J Jackson and Katie Newby

ICD coding of death certificates with generative language models pp. 1-17

Isabel Coutinho, Gonçalo M Correia, Bruno Martins, Afonso Moreira and André Peralta-Santos

SomaVR: A low-cost virtual reality platform and implementation framework for medical education in resource-limited settings pp. 1-17

Mike Nsubuga, Grace Kebirungi, Helen Please, Paul Buyego, Henry Mutegeki, Rodgers Kimera, Jag Dhanda, Phil Cruz, Meghan McCarthy, Darrell Hurt, Maria Y Giovanni, Christopher Whalen, Michael Tartakovsky and Daudi Jjingo

From patient voices to policy: Data analytics reveals patterns in Ontario’s hospital feedback pp. 1-24

Pourya Momtaz, Mohammad Noaeen, Konrad Samsel, Neil Seeman, Robert Cribb, Syed Ishtiaque Ahmed, Amol Verma, Dionne M Aleman and Zahra Shakeri

AI-ECG classification for Brugada syndrome: A study of machine learning techniques to optimise for limited datasets pp. 1-20

Keenan Saleh, Raaif Hadadi, Yixiu Liang, Hong Wong, Arunashis Sau, James Howard, Evan Brittain, Jeffrey Annis, Majd El-Harasis, Matthew Shun-Shin, Jagdeep Mohal, Akriti Naraen, Jack Samways, Jessica Artico, James Ware, Prapa Kanagaratnam, Fu Siong Ng, Massoud Zolgharni, Wenjia Bai, Amanda Varnava, Zachary Whinnett and Ahran Arnold

Development and validation of interpretable multimodal clinical-radiomics models for predicting epileptogenic foci and surgical outcomes in tuberous sclerosis complex: A multicenter study pp. 1-25

Yang Li, Xingye Liu, Jie Li, Mingxun Xie, Shujing Li, Kaixuan Huang, Jiaxi Zhao, Xin Chen, Zeng He, Jing He, Limeng Sun, Renrong Jiang, Chun Cui, Li Wang, Zhonghong Liu, Song Zhang, Haifeng Shu, Shengqing Lv, Chunqing Zhang, Dong Zhang, Di Wang, Hui Yang, Qiang Guo, Hongping Tan, Xiaolin Yang, Shiyong Liu and Zhongke Wang

Narrowing the A1c gap: Personalized modeling of HbA1c– continuous glucose monitor discordance in type 1 diabetes pp. 1-14

Simon Lebech Cichosz, Camilla Heisel Nyholm Thomsen, David C Klonoff, Irl B Hirsch and Morten Hasselstrøm Jensen

Portability of a text mining algorithm for detecting adverse drug reactions in electronic health records across diverse patient groups in two Dutch hospitals pp. 1-14

Britt W M van de Burgt, Loes F C van Dijck, Bjorn Dullemond, Naomi T Jessurun, Minou van Seyen, Rob J van Marum, Remco J A van Wensen, Wai-Yan Liu, Carolien M J van der Linden, Rene J E Grouls, R Arthur Bouwman, Erik H M Korsten and Toine C G Egberts

Sleep and smartphone use: Within and between-person relationships from an objective longitudinal smartphone and wearable data donation study pp. 1-14

Paulien Decorte, Karolien Poels, Cedric Vuye, Jonas Lembrechts, Ablenya Barros, Karolien Couscheir and Gert-Jan De Bruijn

Using big data to search for possible geographic clustering of Congenital Heart Disease (CHD) across Australia pp. 1-11

Calum Nicholson, Geoff Strange and David S Celermajer

Interpretable depression assessment using a large language model pp. 1-18

Jae-Joong Lee, Jihoon Han and Choong-Wan Woo

SHREC: A framework for advancing next-generation computational phenotyping with large language models pp. 1-13

Sarah Pungitore, Shashank Yadav, Molly Douglas, Jarrod Mosier and Vignesh Subbian

Classification of knowledge of fertility period among adolescent girls in East Africa from 2012 to 2022: Machine learning algorithm pp. 1-22

Andualem Addisu Birlie, Kassahun Dessie Gashu, Mulugeta Desalegn Kasaye, Ayana Alebachew Muluneh, Abdulaziz Kebede Kassaw, Hailemariam Kassahun Desalegn, Tamir Wondim Desta and Shimels Derso Kebede

Volume 5, issue 1, 2026

Remote home cardiotocography: A systematic review and meta-analysis pp. 1-26

Jack Le Vance, Adekunle Adeoye, Rebecca Man, Nashwa Eltaweel, Leo Gurney, RKatie Morris and Victoria Hodgetts Morton

Development and evaluation of machine learning algorithms for the prediction of opioid-related deaths among UK patients with non-cancer pain pp. 1-20

Jose Benitez-Aurioles, Carlos Raul Ramirez Medina, David Jenkins, Niels Peek and Meghna Jani

Moving beyond the empty cell: The threat of decontextualized healthcare data pp. 1-9

Aya El Mir, Eric Bezerra de Sousa, Ignacio Mesina-Estarrón, Leo Anthony Celi, Moad Hani, Mohammed Benjelloun, Neha Nageswaran, Saïd Mahmoudi, Shaheen Siddiqui, Sreeram Sadasivam and William Greig Mitchell

A pilot feasibility study of human-centered design for cirrhosis care: Development and pilot testing of SMARTLiver prototype, a FHIR-based clinical decision support system for hepatology pp. 1-19

Keerthika Sunchu, Archita P Desai, Raj Vuppalanchi and Saptarshi Purkayastha

Validation of a markerless motion capture app for automated scoring of sit-to-stand, timed up and go, and short physical performance battery tests in adults with chronic disease pp. 1-19

Jennifer K Bertrand, Margaret L McNeely, Jack Bates, Joshua Joy, Jenil Kanani, Victor E Ezeugwu and Puneeta Tandon

Digitally delivered, systemically challenged: A qualitative study of health system readiness for digital care pp. 1-15

Laurel O’Connor, Leah Dunkel, Andrew C Weitz, Allan Walkey, Peter K Lindenauer and Apurv Soni

Economic cost of strategic implementation approaches to increase uptake of digital therapeutics for substance use disorders in a large integrated health system pp. 1-16

Edwin S Wong, Caitlin N Dorsey, Tara C Beatty, Jennifer F Bobb, Kelsey Stefanik-Guizlo, Dustin L Key, Arvind Ramaprasan, Abisola E Idu, John C Fortney, Jessica Mogk, Lorella Palazzo, Ryan M Caldeiro, Deborah King, Angela Garza McWethy and Joseph E Glass

Hierarchy and hope: Exploring AI’s role in medicine through a thematic analysis of online discourse pp. 1-12

Johan Pushani, Sherwin Rajkumar, Alishya Burrell, Erin Peebles and Amrit Kirpalani