Statistics in Biosciences

2016 - 2025

Current editor(s): Hongyu Zhao and Xihong Lin

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Springer
International Chinese Statistical Association
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Volume 13, issue 3, 2021

A Statistical Method for Association Analysis of Cell Type Compositions pp. 373-385

Licai Huang, Paul Little, Jeroen R. Huyghe, Qian Shi, Tabitha A. Harrison, Greg Yothers, Thomas J. George, Ulrike Peters, Andrew T. Chan, Polly A. Newcomb and Wei Sun

Improved Semiparametric Analysis of Polygenic Gene–Environment Interactions in Case–Control Studies pp. 386-401

Tianying Wang and Alex Asher

An Application of the Cure Model to a Cardiovascular Clinical Trial pp. 402-430

Varadan Sevilimedu, Shuangge Ma, Pamela Hartigan and Tassos C. Kyriakides

RETRACTED ARTICLE: Positive Stable Shared Frailty Models Based on Additive Hazards pp. 431-453

David D. Hanagal

Enhanced Doubly Robust Procedure for Causal Inference pp. 454-478

Ao Yuan, Anqi Yin and Ming T. Tan

Average Response over Time as Estimand: An Alternative Implementation of the While on Treatment Strategy pp. 479-494

Naitee Ting, Lihong Huang, Qiqi Deng and Joseph C. Cappelleri

Spatial Weighted Analysis of Malnutrition Among Children in Nigeria: A Bayesian Approach pp. 495-523

Osafu Augustine Egbon, Omodolapo Somo-Aina and Ezra Gayawan

Intergenerational Associations Between Maternal Diet and Childhood Adiposity: A Bayesian Regularized Mediation Analysis pp. 524-542

Yu-Bo Wang, Cuilin Zhang and Zhen Chen

Penalized Latent Dirichlet Allocation Model in Single-Cell RNA Sequencing pp. 543-562

Xiaotian Wu, Hao Wu and Zhijin Wu

An Efficient Segmentation Algorithm to Estimate Sleep Duration from Actigraphy Data pp. 563-583

Jonggyu Baek, Magaret Banker, Erica C. Jansen, Xichen She, Karen E. Peterson, E. Andrew Pitchford and Peter X. K. Song

Volume 13, issue 2, 2021

Introduction to Special Issue on Statistics in Microbiome and Metagenomics pp. 197-199

Huilin Li and Hongzhe Li

Robust and Powerful Differential Composition Tests for Clustered Microbiome Data pp. 200-216

Zheng-Zheng Tang and Guanhua Chen

Regression Models for Compositional Data: General Log-Contrast Formulations, Proximal Optimization, and Microbiome Data Applications pp. 217-242

Patrick L. Combettes and Christian L. Müller

Modeling Longitudinal Microbiome Compositional Data: A Two-Part Linear Mixed Model with Shared Random Effects pp. 243-266

Yongli Han, Courtney Baker, Emily Vogtmann, Xing Hua, Jianxin Shi and Danping Liu

An Approach to Analyze Longitudinal Zero-Inflated Microbiome Count Data Using Two-Stage Mixed Effects Models pp. 267-290

Jian Wang, Cielito C. Reyes-Gibby and Sanjay Shete

Distance-Based Analysis with Quantile Regression Models pp. 291-312

Shaoyu Li, Yanqing Sun, Liyang Diao and Xue Wang

Testing for Mediation Effect with Application to Human Microbiome Data pp. 313-328

Haixiang Zhang, Jun Chen, Zhigang Li and Lei Liu

Microbial Interaction Network Estimation via Bias-Corrected Graphical Lasso pp. 329-350

Duo Jiang, Thomas Sharpton and Yuan Jiang

Joint Microbial and Metabolomic Network Estimation with the Censored Gaussian Graphical Model pp. 351-372

Jing Ma

Volume 13, issue 1, 2021

On a Statistical Transmission Model in Analysis of the Early Phase of COVID-19 Outbreak pp. 1-17

Yifan Zhu and Ying Qing Chen

A Super Scalable Algorithm for Short Segment Detection pp. 18-33

Ning Hao, Yue Selena Niu, Feifei Xiao and Heping Zhang

A General Approach to Sensitivity Analysis for Mendelian Randomization pp. 34-55

Weiming Zhang and Debashis Ghosh

Joint Spatial Modelling of Childhood Morbidity in West Africa Using a Distributional Bivariate Probit Model pp. 56-76

Ezra Gayawan and Funmilayo Adenike Fadiji

Chi-Square Type Goodness-of-Fit Test for Hazard Rate pp. 77-89

Ralph-Antoine Vital and Prakash N. Patil

Quantile-Based Subgroup Identification for Randomized Clinical Trials pp. 90-128

Youngjoo Cho and Debashis Ghosh

Bayesian Quantile Bent-Cable Growth Models for Longitudinal Data with Skewness and Detection Limit pp. 129-141

Getachew A. Dagne

Competing Risks Model with Short-Term and Long-Term Covariate Effects for Cancer Studies pp. 142-159

Guoqing Diao, Anand N. Vidyashankar, Sarah Zohar and Sandrine Katsahian

Can the Concept Be Proven? pp. 160-177

Ying-Ying Zhang and Naitee Ting

Regression Analysis of Mixed Panel-Count Data with Application to Cancer Studies pp. 178-195

Yimei Li, Liang Zhu, Lei Liu and Leslie L. Robison

Volume 12, issue 3, 2020

Introduction to Special Issue on ‘Statistical Methods for HIV/AIDS Research’ pp. 263-266

Ying Qing Chen

A Method for Estimating the Proportion of HIV-Infected Persons That Have Been Diagnosed and Application to China pp. 267-278

Ron Brookmeyer and Zunyou Wu

Comparison of HIV Prevalence Among Antenatal Clinic Attendees Estimated from Routine Testing and Unlinked Anonymous Testing pp. 279-294

Ben Sheng, Jeffrey W. Eaton, Mary Mahy and Le Bao

Measuring Surrogacy in Clinical Research pp. 295-323

Rui Zhuang and Ying Qing Chen

Generating Survival Times Using Cox Proportional Hazards Models with Cyclic and Piecewise Time-Varying Covariates pp. 324-339

Yunda Huang, Yuanyuan Zhang, Zong Zhang and Peter B. Gilbert

On a Shape-Invariant Hazard Regression Model with application to an HIV Prevention Study of Mother-to-Child Transmission pp. 340-352

Cheng Zheng and Ying Qing Chen

Methods for Feature Selection in Down-Selection of Vaccine Regimens Based on Multivariate Immune Response Endpoints pp. 353-375

Ying Huang and Aliasghar Tarkhan

Variable Selection in Threshold Regression Model with Applications to HIV Drug Adherence Data pp. 376-398

Takumi Saegusa, Tianzhou Ma, Gang Li, Ying Qing Chen and Mei-Ling Ting Lee

A Simulation Study of Statistical Approaches to Data Analysis in the Stepped Wedge Design pp. 399-415

Yuqi Ren, James P. Hughes and Patrick J. Heagerty

Correction to: A Simulation Study of Statistical Approaches to Data Analysis in the Stepped Wedge Design pp. 416-416

Yuqi Ren, James P. Hughes and Patrick J. Heagerty

Deductive Semiparametric Estimation in Double-Sampling Designs with Application to PEPFAR pp. 417-445

Tianchen Qian, Constantine Frangakis and Constantin Yiannoutsos

Design and Analysis Considerations for a Sequentially Randomized HIV Prevention Trial pp. 446-467

David Benkeser, Keith Horvath, Cathy J. Reback, Joshua Rusow and Michael Hudgens

Designing HIV Vaccine Efficacy Trials in the Context of Highly Effective Non-vaccine Prevention Modalities pp. 468-494

Holly Janes, Yifan Zhu and Elizabeth R. Brown

Volume 12, issue 2, 2020

Introduction to Special Issue on ‘Statistical Methods for Cancer Immunotherapy’ pp. 79-82

Bo Huang and Naitee Ting

Assessing Treatment Benefit in Immuno-oncology pp. 83-103

Marc Buyse, Everardo D. Saad, Tomasz Burzykowski and Julien Péron

Flexible Phase I–II Design for Partially Ordered Regimens with Application to Therapeutic Cancer Vaccines pp. 104-123

Nolan A. Wages and Craig L. Slingluff

PoD-TPI: Probability-of-Decision Toxicity Probability Interval Design to Accelerate Phase I Trials pp. 124-145

Tianjian Zhou, Wentian Guo and Yuan Ji

A Curve-Free Bayesian Decision-Theoretic Design for Phase Ia/Ib Trials Considering Both Safety and Efficacy Outcomes pp. 146-166

Shenghua Fan, Bee Leng Lee and Ying Lu

A Bayesian Method for the Detection of Proof of Concept in Early Phase Oncology Studies with a Basket Design pp. 167-179

Jin Jin, Qianying Liu, Wei Zheng, Zhenming Shun, Tun Tun Lin, Lei Gao and Yingwen Dong

On the Use of Marker Strategy Design to Detect Predictive Marker Effect in Cancer Immunotherapy and Targeted Therapy pp. 180-195

Yan Han, Ying Yuan, Sha Cao, Muyi Li and Yong Zang

Impact of Clinical Center Variation on Efficiency of Exploratory Umbrella Design pp. 196-215

Fang Liu, Nicole Li, Wen Li and Cong Chen

Some Meaningful Weighted Log-Rank and Weighted Win Loss Statistics pp. 216-224

Xiaodong Luo and Hui Quan

On Weighted Log-Rank Combination Tests and Companion Cox Model Estimators pp. 225-245

Larry F. León, Ray Lin and Keaven M. Anderson

Efficient Estimation of Mann–Whitney-Type Effect Measures for Right-Censored Survival Outcomes in Randomized Clinical Trials pp. 246-262

Zhiwei Zhang, Wei Li and Hui Zhang

Volume 12, issue 1, 2020

Two-Way Horizontal and Vertical Omics Integration for Disease Subtype Discovery pp. 1-22

Zhiguang Huo, Li Zhu, Tianzhou Ma, Hongcheng Liu, Song Han, Daiqing Liao, Jinying Zhao and George Tseng

A Likelihood-Based Approach for the Analysis of Longitudinal Clinical Trials with Return-to-Baseline Imputation pp. 23-36

Yilong Zhang, Gregory Golm and Guanghan Liu

A Mixture Model for Bivariate Interval-Censored Failure Times with Dependent Susceptibility pp. 37-62

Shu Jiang and Richard J. Cook

A Geometry-Based Multiple Testing Correction for Contingency Tables by Truncated Normal Distribution pp. 63-77

Tapati Basak, Kazuhisa Nagashima, Satoshi Kajimoto, Takahisa Kawaguchi, Yasuharu Tabara, Fumihiko Matsuda and Ryo Yamada