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Statistics in Biosciences

2016 - 2026

Current editor(s): Hongyu Zhao and Xihong Lin

From:
Springer
International Chinese Statistical Association
Bibliographic data for series maintained by Sonal Shukla () and Springer Nature Abstracting and Indexing ().

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Volume 14, issue 3, 2022

A Weighted Sample Framework to Incorporate External Calculators for Risk Modeling pp. 363-379 Downloads
Debashis Ghosh and Michael S. Sabel
A New Bayesian Two-Sample t Test and Solution to the Behrens–Fisher Problem Based on Gaussian Mixture Modelling with Known Allocations pp. 380-412 Downloads
Riko Kelter
Efficacy-Driven Dose Finding with Toxicity Control in Phase I Oncology Studies pp. 413-431 Downloads
Qingyang Liu, Junxian Geng, Frank Fleischer and Qiqi Deng
High-Dimensional Mediation Analysis with Applications to Causal Gene Identification pp. 432-451 Downloads
Qi Zhang
A Model-Based Approach to Assess Epidemic Risk pp. 452-484 Downloads
Hugo Dolan and Riccardo Rastelli
Characterizing Spatiotemporal Transcriptome of the Human Brain Via Low-Rank Tensor Decomposition pp. 485-513 Downloads
Tianqi Liu, Ming Yuan and Hongyu Zhao
Epistasis Detection via the Joint Cumulant pp. 514-532 Downloads
Randall Reese, Guifang Fu, Geran Zhao, Xiaotian Dai, Xiaotian Li and Kenneth Chiu
Fast Multivariate Probit Estimation via a Two-Stage Composite Likelihood pp. 533-549 Downloads
Bryan Ting, Fred Wright and Yi-Hui Zhou
Estimation of the Proportional Mean Residual Life Model with Internal and Longitudinal Covariates pp. 550-563 Downloads
Ruiwen Zhou and Jianguo Sun
Targeted Search for Individualized Clinical Decision Rules to Optimize Clinical Outcomes pp. 564-581 Downloads
Yanqing Wang, Yingqi Zhao and Yingye Zheng
A Generalized Interrupted Time Series Model for Assessing Complex Health Care Interventions pp. 582-610 Downloads
Maricela Cruz, Hernando Ombao and Daniel L. Gillen

Volume 14, issue 2, 2022

Introduction to Special Issue on Leveraging External Data to Improve Trial Efficiency pp. 193-196 Downloads
Lanju Zhang and Naitee Ting
Flexible Conditional Borrowing Approaches for Leveraging Historical Data in the Bayesian Design of Superiority Trials pp. 197-215 Downloads
Wenlin Yuan, Ming-Hui Chen and John Zhong
A Simple Approach to Incorporating Historical Control Data in Clinical Trial Design and Analysis pp. 216-236 Downloads
Lanju Zhang, Zailong Wang, Li Wang, Lu Cui, Jeremy Sokolove and Ivan Chan
Leveraging Natural History Data in One- and Two-Arm Hierarchical Bayesian Studies of Rare Disease Progression pp. 237-258 Downloads
Arnaud Monseur, Bradley P. Carlin, Bruno Boulanger, Andreea Seferian, Laurent Servais, Chris Freitag and Leen Thielemans
A Simulation-Based Evaluation of Statistical Methods for Hybrid Real-World Control Arms in Clinical Trials pp. 259-284 Downloads
Mingyang Shan, Douglas Faries, Andy Dang, Xiang Zhang, Zhanglin Cui and Kristin M. Sheffield
Building an External Control Arm for Development of a New Molecular Entity: An Application in a Recurrent Glioblastoma Trial for MDNA55 pp. 285-303 Downloads
Antara Majumdar, Ruthanna Davi, Martin Bexon, Chandtip Chandhasin, Melissa Coello, Fahar Merchant and Nina Merchant
Clinical Trials with External Control: Beyond Propensity Score Matching pp. 304-317 Downloads
Hongwei Wang, Yixin Fang, Weili He, Ruizhe Chen and Su Chen
A Power Prior Approach for Leveraging External Longitudinal and Competing Risks Survival Data Within the Joint Modeling Framework pp. 318-336 Downloads
Md. Tuhin Sheikh, Ming-Hui Chen, Jonathan A. Gelfond and Joseph G. Ibrahim
Improving Early Futility Determination by Learning from External Data in Pediatric Cancer Clinical Trials pp. 337-351 Downloads
Jingjing Ye and Gregory Reaman
Optimal Biomarker Cutoff Identification and Validation pp. 352-362 Downloads
Jianan Hui and Wenchuan Guo

Volume 14, issue 1, 2022

Discriminatory Capacity of Prenatal Ultrasound Measures for Large-for-Gestational-Age Birth: A Bayesian Approach to ROC Analysis Using Placement Values pp. 1-22 Downloads
Soutik Ghosal and Zhen Chen
Using Copulas for Bayesian Meta-analysis pp. 23-41 Downloads
Savita Jain, Suresh K. Sharma and Kanchan Jain
Correlated Positive Stable Frailty Models Based on Reversed Hazard Rate pp. 42-65 Downloads
David D. Hanagal
Exposure Adjusted Incidence Rate and Event Rate in Clinical Trials with Treatment Crossover pp. 66-78 Downloads
Yunxia Sui, Ruofei Zhao, Yihan Li and Xin Wang
Augmenting Both Arms of a Randomized Controlled Trial Using External Data: An Application of the Propensity Score-Integrated Approaches pp. 79-89 Downloads
Heng Li, Wei-Chen Chen, Chenguang Wang, Nelson Lu, Changhong Song, Ram Tiwari, Yunling Xu and Lilly Q. Yue
Sample Size Re-estimation with the Com-Nougue Method to Evaluate Treatment Effect pp. 90-103 Downloads
Jin Wang
Correction to: Sample Size Re-estimation with the Com-Nougue Method to Evaluate Treatment Effect pp. 104-104 Downloads
Jin Wang
Estimation of Discrete Survival Function through Modeling Diagnostic Accuracy for Mismeasured Outcome Data pp. 105-138 Downloads
Hee-Koung Joeng, Abidemi K. Adeniji, Naitee Ting and Ming-Hui Chen
Assessments of Conditional and Unconditional Type I Error Probabilities for Bayesian Hypothesis Testing with Historical Data Borrowing pp. 139-157 Downloads
Hui Quan, Xiaofei Chen, Xun Chen and Xiaodong Luo
Optimal and/or Efficient Cross-Over Designs Balanced for Carry-Over of Active Treatments pp. 158-174 Downloads
Jigneshkumar Gondaliya and Jyoti Divecha
Is 14-Days a Sensible Quarantine Length for COVID-19? Examinations of Some Associated Issues with a Case Study of COVID-19 Incubation Times pp. 175-190 Downloads
Yasin Khadem Charvadeh, Grace Y. Yi, Yuan Bian and Wenqing He
Correction to: Is 14-Days a Sensible Quarantine Length for COVID-19? Examinations of Some Associated Issues with a Case Study of COVID-19 Incubation Times pp. 191-191 Downloads
Yasin Khadem Charvadeh, Grace Y. Yi, Yuan Bian and Wenqing He

Volume 13, issue 3, 2021

A Statistical Method for Association Analysis of Cell Type Compositions pp. 373-385 Downloads
Licai Huang, Paul Little, Jeroen R. Huyghe, Qian Shi, Tabitha A. Harrison, Greg Yothers, Thomas J. George, Ulrike Peters, Andrew T. Chan, Polly A. Newcomb and Wei Sun
Improved Semiparametric Analysis of Polygenic Gene–Environment Interactions in Case–Control Studies pp. 386-401 Downloads
Tianying Wang and Alex Asher
An Application of the Cure Model to a Cardiovascular Clinical Trial pp. 402-430 Downloads
Varadan Sevilimedu, Shuangge Ma, Pamela Hartigan and Tassos C. Kyriakides
RETRACTED ARTICLE: Positive Stable Shared Frailty Models Based on Additive Hazards pp. 431-453 Downloads
David D. Hanagal
Enhanced Doubly Robust Procedure for Causal Inference pp. 454-478 Downloads
Ao Yuan, Anqi Yin and Ming T. Tan
Average Response over Time as Estimand: An Alternative Implementation of the While on Treatment Strategy pp. 479-494 Downloads
Naitee Ting, Lihong Huang, Qiqi Deng and Joseph C. Cappelleri
Spatial Weighted Analysis of Malnutrition Among Children in Nigeria: A Bayesian Approach pp. 495-523 Downloads
Osafu Augustine Egbon, Omodolapo Somo-Aina and Ezra Gayawan
Intergenerational Associations Between Maternal Diet and Childhood Adiposity: A Bayesian Regularized Mediation Analysis pp. 524-542 Downloads
Yu-Bo Wang, Cuilin Zhang and Zhen Chen
Penalized Latent Dirichlet Allocation Model in Single-Cell RNA Sequencing pp. 543-562 Downloads
Xiaotian Wu, Hao Wu and Zhijin Wu
An Efficient Segmentation Algorithm to Estimate Sleep Duration from Actigraphy Data pp. 563-583 Downloads
Jonggyu Baek, Magaret Banker, Erica C. Jansen, Xichen She, Karen E. Peterson, E. Andrew Pitchford and Peter X. K. Song

Volume 13, issue 2, 2021

Introduction to Special Issue on Statistics in Microbiome and Metagenomics pp. 197-199 Downloads
Huilin Li and Hongzhe Li
Robust and Powerful Differential Composition Tests for Clustered Microbiome Data pp. 200-216 Downloads
Zheng-Zheng Tang and Guanhua Chen
Regression Models for Compositional Data: General Log-Contrast Formulations, Proximal Optimization, and Microbiome Data Applications pp. 217-242 Downloads
Patrick L. Combettes and Christian L. Müller
Modeling Longitudinal Microbiome Compositional Data: A Two-Part Linear Mixed Model with Shared Random Effects pp. 243-266 Downloads
Yongli Han, Courtney Baker, Emily Vogtmann, Xing Hua, Jianxin Shi and Danping Liu
An Approach to Analyze Longitudinal Zero-Inflated Microbiome Count Data Using Two-Stage Mixed Effects Models pp. 267-290 Downloads
Jian Wang, Cielito C. Reyes-Gibby and Sanjay Shete
Distance-Based Analysis with Quantile Regression Models pp. 291-312 Downloads
Shaoyu Li, Yanqing Sun, Liyang Diao and Xue Wang
Testing for Mediation Effect with Application to Human Microbiome Data pp. 313-328 Downloads
Haixiang Zhang, Jun Chen, Zhigang Li and Lei Liu
Microbial Interaction Network Estimation via Bias-Corrected Graphical Lasso pp. 329-350 Downloads
Duo Jiang, Thomas Sharpton and Yuan Jiang
Joint Microbial and Metabolomic Network Estimation with the Censored Gaussian Graphical Model pp. 351-372 Downloads
Jing Ma

Volume 13, issue 1, 2021

On a Statistical Transmission Model in Analysis of the Early Phase of COVID-19 Outbreak pp. 1-17 Downloads
Yifan Zhu and Ying Qing Chen
A Super Scalable Algorithm for Short Segment Detection pp. 18-33 Downloads
Ning Hao, Yue Selena Niu, Feifei Xiao and Heping Zhang
A General Approach to Sensitivity Analysis for Mendelian Randomization pp. 34-55 Downloads
Weiming Zhang and Debashis Ghosh
Joint Spatial Modelling of Childhood Morbidity in West Africa Using a Distributional Bivariate Probit Model pp. 56-76 Downloads
Ezra Gayawan and Funmilayo Adenike Fadiji
Chi-Square Type Goodness-of-Fit Test for Hazard Rate pp. 77-89 Downloads
Ralph-Antoine Vital and Prakash N. Patil
Quantile-Based Subgroup Identification for Randomized Clinical Trials pp. 90-128 Downloads
Youngjoo Cho and Debashis Ghosh
Bayesian Quantile Bent-Cable Growth Models for Longitudinal Data with Skewness and Detection Limit pp. 129-141 Downloads
Getachew A. Dagne
Competing Risks Model with Short-Term and Long-Term Covariate Effects for Cancer Studies pp. 142-159 Downloads
Guoqing Diao, Anand N. Vidyashankar, Sarah Zohar and Sandrine Katsahian
Can the Concept Be Proven? pp. 160-177 Downloads
Ying-Ying Zhang and Naitee Ting
Regression Analysis of Mixed Panel-Count Data with Application to Cancer Studies pp. 178-195 Downloads
Yimei Li, Liang Zhu, Lei Liu and Leslie L. Robison
Page updated 2026-02-21