PLOS Biology

2003 - 2022

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Volume 18, issue 12, 2020

LSM12-EPAC1 defines a neuroprotective pathway that sustains the nucleocytoplasmic RAN gradient pp. 1-35

Jongbo Lee, Jumin Park, Ji-hyung Kim, Giwook Lee, Tae-Eun Park, Ki-Jun Yoon, Yoon Ki Kim and Chunghun Lim

Clustering of Tir during enteropathogenic E. coli infection triggers calcium influx–dependent pyroptosis in intestinal epithelial cells pp. 1-31

Qiyun Zhong, Theodoros I Roumeliotis, Zuza Kozik, Massiel Cepeda-Molero, Luis Ángel Fernández, Avinash R Shenoy, Chris Bakal, Gad Frankel and Jyoti S Choudhary

The actions of others act as a pseudo-reward to drive imitation in the context of social reinforcement learning pp. 1-25

Anis Najar, Emmanuelle Bonnet, Bahador Bahrami and Stefano Palminteri

Regulation of glial size by eicosapentaenoic acid through a novel Golgi apparatus mechanism pp. 1-25

Albert Zhang, Ziqiang Guan, Kyle Ockerman, Pengyuan Dong, Jiansheng Guo, Zhiping Wang and Dong Yan

Patterns of smallpox mortality in London, England, over three centuries pp. 1-27

Olga Krylova and David J D Earn

Reoccurring neural stem cell divisions in the adult zebrafish telencephalon are sufficient for the emergence of aggregated spatiotemporal patterns pp. 1-23

Valerio Lupperger, Carsten Marr and Prisca Chapouton

Ensuring the quality and specificity of preregistrations pp. 1-18

Marjan Bakker, Coosje L S Veldkamp, Marcel A L M van Assen, Elise A V Crompvoets, How Hwee Ong, Brian A Nosek, Courtney K Soderberg, David Mellor and Jelte M Wicherts

Design of novel granulopoietic proteins by topological rescaffolding pp. 1-26

Birte Hernandez Alvarez, Julia Skokowa, Murray Coles, Perihan Mir, Masoud Nasri, Kateryna Maksymenko, Laura Weidmann, Katherine W Rogers, Karl Welte, Andrei N Lupas, Patrick Müller and Mohammad ElGamacy

Generalizable brain network markers of major depressive disorder across multiple imaging sites pp. 1-26

Ayumu Yamashita, Yuki Sakai, Takashi Yamada, Noriaki Yahata, Akira Kunimatsu, Naohiro Okada, Takashi Itahashi, Ryuichiro Hashimoto, Hiroto Mizuta, Naho Ichikawa, Masahiro Takamura, Go Okada, Hirotaka Yamagata, Kenichiro Harada, Koji Matsuo, Saori C Tanaka, Mitsuo Kawato, Kiyoto Kasai, Nobumasa Kato, Hidehiko Takahashi, Yasumasa Okamoto, Okito Yamashita and Hiroshi Imamizu

Volume 18, issue 11, 2020

Rules warp feature encoding in decision-making circuits pp. 1-38

R Becket Ebitz, Jiaxin Cindy Tu and Benjamin Y Hayden

EphrinB1 modulates glutamatergic inputs into POMC-expressing progenitors and controls glucose homeostasis pp. 1-24

Manon Gervais, Gwenaël Labouèbe, Alexandre Picard, Bernard Thorens and Sophie Croizier

Many, but not all, lineage-specific genes can be explained by homology detection failure pp. 1-24

Caroline M Weisman, Andrew W Murray and Sean R Eddy

We need to keep a reproducible trace of facts, predictions, and hypotheses from gene to function in the era of big data pp. 1-10

Simon Kasif and Richard J Roberts

Temporal coding of echo spectral shape in the bat auditory cortex pp. 1-21

Silvio Macias, Kushal Bakshi, Francisco Garcia-Rosales, Julio C Hechavarria and Michael Smotherman

SiCTeC: An inexpensive, easily assembled Peltier device for rapid temperature shifting during single-cell imaging pp. 1-17

Benjamin D Knapp, Lillian Zhu and Kerwyn Casey Huang

Unifying the mechanism of mitotic exit control in a spatiotemporal logical model pp. 1-35

Rowan S M Howell, Cinzia Klemm, Peter H Thorpe and Attila Csikász-Nagy

NOX5-induced uncoupling of endothelial NO synthase is a causal mechanism and theragnostic target of an age-related hypertension endotype pp. 1-25

Mahmoud H Elbatreek, Sepideh Sadegh, Elisa Anastasi, Emre Guney, Cristian Nogales, Tim Kacprowski, Ahmed A Hassan, Andreas Teubner, Po-Hsun Huang, Chien-Yi Hsu, Paul M H Schiffers, Ger M Janssen, Pamela W M Kleikers, Anil Wipat, Jan Baumbach, Jo G R De Mey and Harald H H W Schmidt

Volume 18, issue 10, 2020

The COVID-19 response illustrates that traditional academic reward structures and metrics do not reflect crucial contributions to modern science pp. 1-3

Adam J Kucharski, Sebastian Funk and Rosalind M Eggo

Updated science-wide author databases of standardized citation indicators pp. 1-3

John P A Ioannidis, Kevin W Boyack and Jeroen Baas

Optimising risk-based surveillance for early detection of invasive plant pathogens pp. 1-25

Alexander J Mastin, Timothy R Gottwald, Frank van den Bosch, Nik J Cunniffe and Stephen Parnell

Neural activity during a simple reaching task in macaques is counter to gating and rebound in basal ganglia–thalamic communication pp. 1-38

Bettina C Schwab, Daisuke Kase, Andrew Zimnik, Robert Rosenbaum, Marcello G Codianni, Jonathan E Rubin and Robert S Turner

Volume 18, issue 9, 2020

High-coverage plasma lipidomics reveals novel sex-specific lipidomic fingerprints of age and BMI: Evidence from two large population cohort studies pp. 1-37

Habtamu B Beyene, Gavriel Olshansky, Adam Alexander T. Smith, Corey Giles, Kevin Huynh, Michelle Cinel, Natalie A Mellett, Gemma Cadby, Joseph Hung, Jennie Hui, John Beilby, Gerald F Watts, Jonathan S Shaw, Eric K Moses, Dianna J Magliano and Peter J Meikle

Quantifying and contextualizing the impact of bioRxiv preprints through automated social media audience segmentation pp. 1-23

Jedidiah Carlson and Kelley Harris

Evolutionary dynamics in the Anthropocene: Life history and intensity of human contact shape antipredator responses pp. 1-17

Benjamin Geffroy, Bastien Sadoul, Breanna J Putman, Oded Berger-Tal, László Zsolt Garamszegi, Anders Pape Møller and Daniel T Blumstein

Controlling control—A primer in open-source experimental control systems pp. 1-7

Christopher James Forman

Volume 18, issue 8, 2020

The right temporoparietal junction enables delay of gratification by allowing decision makers to focus on future events pp. 1-20

Alexander Soutschek, Marius Moisa, Christian C Ruff and Philippe N Tobler

Recommendations for future university pandemic responses: What the first COVID-19 shutdown taught us pp. 1-6

Carolyn Coyne, Jimmy D Ballard and Ira J Blader

Volume 18, issue 7, 2020

The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research pp. 1-12

Nathalie Percie du Sert, Viki Hurst, Amrita Ahluwalia, Sabina Alam, Marc T Avey, Monya Baker, William J Browne, Alejandra Clark, Innes C Cuthill, Ulrich Dirnagl, Michael Emerson, Paul Garner, Stephen T Holgate, David W Howells, Natasha A Karp, Stanley E Lazic, Katie Lidster, Catriona J MacCallum, Malcolm Macleod, Esther J Pearl, Ole H Petersen, Frances Rawle, Penny Reynolds, Kieron Rooney, Emily S Sena, Shai D Silberberg, Thomas Steckler and Hanno Würbel

Should a viral genome stay in the host cell or leave? A quantitative dynamics study of how hepatitis C virus deals with this dilemma pp. 1-17

Shoya Iwanami, Kosaku Kitagawa, Hirofumi Ohashi, Yusuke Asai, Kaho Shionoya, Wakana Saso, Kazane Nishioka, Hisashi Inaba, Shinji Nakaoka, Takaji Wakita, Odo Diekmann, Shingo Iwami and Koichi Watashi

The Hong Kong Principles for assessing researchers: Fostering research integrity pp. 1-14

David Moher, Lex Bouter, Sabine Kleinert, Paul Glasziou, Mai Har Sham, Virginia Barbour, Anne-Marie Coriat, Nicole Foeger and Ulrich Dirnagl

Low availability of code in ecology: A call for urgent action pp. 1-9

Antica Culina, Ilona van den Berg, Simon Evans and Alfredo Sánchez-Tójar

Reporting animal research: Explanation and elaboration for the ARRIVE guidelines 2.0 pp. 1-65

Nathalie Percie du Sert, Amrita Ahluwalia, Sabina Alam, Marc T Avey, Monya Baker, William J Browne, Alejandra Clark, Innes C Cuthill, Ulrich Dirnagl, Michael Emerson, Paul Garner, Stephen T Holgate, David W Howells, Viki Hurst, Natasha A Karp, Stanley E Lazic, Katie Lidster, Catriona J MacCallum, Malcolm Macleod, Esther J Pearl, Ole H Petersen, Frances Rawle, Penny Reynolds, Kieron Rooney, Emily S Sena, Shai D Silberberg, Thomas Steckler and Hanno Würbel

Volume 18, issue 6, 2020

Modulation of bacterial multicellularity via spatio-specific polysaccharide secretion pp. 1-31

Salim T Islam, Israel Vergara Alvarez, Fares Saïdi, Annick Guiseppi, Evgeny Vinogradov, Gaurav Sharma, Leon Espinosa, Castrese Morrone, Gael Brasseur, Jean-François Guillemot, Anaïs Benarouche, Jean-Luc Bridot, Gokulakrishnan Ravicoularamin, Alain Cagna, Charles Gauthier, Mitchell Singer, Henri-Pierre Fierobe, Tâm Mignot and Emilia M F Mauriello

Volume 18, issue 5, 2020

The evolution of the type VI secretion system as a disintegration weapon pp. 1-26

William P J Smith, Andrea Vettiger, Julius Winter, Till Ryser, Laurie E Comstock, Marek Basler and Kevin R Foster

Anticipation-induced delta phase reset improves human olfactory perception pp. 1-26

Ghazaleh Arabkheradmand, Guangyu Zhou, Torben Noto, Qiaohan Yang, Stephan U Schuele, Josef Parvizi, Jay A Gottfried, Shasha Wu, Joshua M Rosenow, Mohamad Z Koubeissi, Gregory Lane and Christina Zelano

Dynamical footprints enable detection of disease emergence pp. 1-20

Tobias S Brett and Pejman Rohani

Antibiotics can be used to contain drug-resistant bacteria by maintaining sufficiently large sensitive populations pp. 1-20

Elsa Hansen, Jason Karslake, Robert J Woods, Andrew F Read and Kevin B Wood

Volume 18, issue 4, 2020

Leveraging open hardware to alleviate the burden of COVID-19 on global health systems pp. 1-17

Andre Maia Chagas, Jennifer C Molloy, Lucia L Prieto-Godino and Tom Baden

Every fifth published metagenome is not available to science pp. 1-7

Ester M Eckert, Andrea Di Cesare, Diego Fontaneto, Thomas U Berendonk, Helmut Bürgmann, Eddie Cytryn, Despo Fatta-Kassinos, Andrea Franzetti, D G Joakim Larsson, Célia M Manaia, Amy Pruden, Andrew C Singer, Nikolina Udikovic-Kolic and Gianluca Corno

Volume 18, issue 3, 2020

Drifting codes within a stable coding scheme for working memory pp. 1-19

Michael J Wolff, Janina Jochim, Elkan G Akyürek, Timothy J Buschman and Mark G Stokes

Frontloading selectivity: A third way in scientific publishing? pp. 1-4

Christopher D Chambers

Context effects on probability estimation pp. 1-45

Wei-Hsiang Lin, Justin L Gardner and Shih-Wei Wu

Eco-evolutionary significance of “loners” pp. 1-27

Fernando W Rossine, Ricardo Martinez-Garcia, Allyson E Sgro, Thomas Gregor and Corina E Tarnita

Interactive youth science workshops benefit student participants and graduate student mentors pp. 1-10

Pallavi Kompella, Brant Gracia, Lucy LeBlanc, Shelly Engelman, Chinmayee Kulkarni, Niral Desai, Viviana June, Stephen March, Sarah Pattengale, Gabriel Rodriguez-Rivera, Seung Woo Ryu, Isabel Strohkendl, Pooja Mandke and Greg Clark

What is replication? pp. 1-8

Brian A Nosek and Timothy M Errington

Preregistration of exploratory research: Learning from the golden age of discovery pp. 1-6

Ulrich Dirnagl

The future of PLOS Biology pp. 1-2

Nonia Pariente and on behalf of the PLOS Biology Staff Editors

Bacterially produced metabolites protect C. elegans neurons from degeneration pp. 1-31

Arles Urrutia, Víctor A García-Angulo, Andrés Fuentes, Mauricio Caneo, Marcela Legüe, Sebastián Urquiza, Scarlett E Delgado, Juan Ugalde, Paula Burdisso and Andrea Calixto

Volume 18, issue 2, 2020

Improving the trustworthiness, usefulness, and ethics of biomedical research through an innovative and comprehensive institutional initiative pp. 1-9

Daniel Strech, Tracey Weissgerber, Ulrich Dirnagl and on behalf of QUEST Group

Macroalgal germplasm banking for conservation, food security, and industry pp. 1-10

Rachael Wade, Simona Augyte, Maddelyn Harden, Sergey Nuzhdin, Charles Yarish and Filipe Alberto

Volume 18, issue 1, 2020

PlotTwist: A web app for plotting and annotating continuous data pp. 1-10

Joachim Goedhart

ATRX affects the repair of telomeric DSBs by promoting cohesion and a DAXX-dependent activity pp. 1-28

Courtney A Lovejoy, Kaori Takai, Michael S Huh, David J Picketts and Titia de Lange

Dating genomic variants and shared ancestry in population-scale sequencing data pp. 1-26

Patrick K Albers and Gil McVean