PLOS Biology

2003 - 2025

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Volume 20, issue 12, 2022

Analysis of the evolution of resistance to multiple antibiotics enables prediction of the Escherichia coli phenotype-based fitness landscape pp. 1-19

Junichiro Iwasawa, Tomoya Maeda, Atsushi Shibai, Hazuki Kotani, Masako Kawada and Chikara Furusawa

Differences in the functional brain architecture of sustained attention and working memory in youth and adults pp. 1-33

Omid Kardan, Andrew J Stier, Carlos Cardenas-Iniguez, Kathryn E Schertz, Julia C Pruin, Yuting Deng, Taylor Chamberlain, Wesley J Meredith, Xihan Zhang, Jillian E Bowman, Tanvi Lakhtakia, Lucy Tindel, Emily W Avery, Qi Lin, Kwangsun Yoo, Marvin M Chun, Marc G Berman and Monica D Rosenberg

Integrated neural dynamics of sensorimotor decisions and actions pp. 1-31

David Thura, Jean-François Cabana, Albert Feghaly and Paul Cisek

Threat management priorities for conserving Antarctic biodiversity pp. 1-31

Jasmine R Lee, Aleks Terauds, Josie Carwardine, Justine D Shaw, Richard A Fuller, Hugh P Possingham, Steven L Chown, Peter Convey, Neil Gilbert, Kevin A Hughes, Ewan McIvor, Sharon A Robinson, Yan Ropert-Coudert, Dana M Bergstrom, Elisabeth M Biersma, Claire Christian, Don A Cowan, Yves Frenot, Stéphanie Jenouvrier, Lisa Kelley, Michael J Lee, Heather J Lynch, Birgit Njåstad, Antonio Quesada, Ricardo M Roura, E Ashley Shaw, Damon Stanwell-Smith, Megumu Tsujimoto, Diana H Wall, Annick Wilmotte and Iadine Chadès

APOE alleles are associated with sex-specific structural differences in brain regions affected in Alzheimer’s disease and related dementia pp. 1-46

Chloé Savignac, Sylvia Villeneuve, AmanPreet Badhwar, Karin Saltoun, Kimia Shafighi, Chris Zajner, Vaibhav Sharma, Sarah A Gagliano Taliun, Sali Farhan, Judes Poirier and Danilo Bzdok

Volume 20, issue 11, 2022

Systematic assessment of the replicability and generalizability of preclinical findings: Impact of protocol harmonization across laboratory sites pp. 1-19

María Arroyo-Araujo, Bernhard Voelkl, Clément Laloux, Janja Novak, Bastijn Koopmans, Ann-Marie Waldron, Isabel Seiffert, Helen Stirling, Katharina Aulehner, Sanna K Janhunen, Sylvie Ramboz, Heidrun Potschka, Johanna Holappa, Tania Fine, Maarten Loos, Bruno Boulanger, Hanno Würbel and Martien J Kas

Reanalysis shows there is not an extreme decline effect in fish ocean acidification studies pp. 1-5

Philip L Munday

Citizen-led expeditions can generate scientific knowledge and prospects for researchers pp. 1-5

Eduardo Sampaio and Victor Rault

Volume 20, issue 10, 2022

Finding logic models for sustainable marine development that deliver on social equity pp. 1-17

Yoshitaka Ota, Gerald G Singh, Timothy Clark, Marleen S Schutter, Wilf Swartz and Andrés M Cisneros-Montemayor

Tackling the mangrove restoration challenge pp. 1-15

Catherine E Lovelock, Edward Barbier and Carlos M Duarte

Five actionable pillars to engage the next generation of leaders in the co-design of transformative ocean solutions pp. 1-14

Erin V Satterthwaite, Valeriya Komyakova, Natalia G Erazo, Louise Gammage, Gabriel A Juma, Rachel Kelly, Daniel Kleinman, Delphine Lobelle, Rachel Sapery James and Norlaila Binti Mohd Zanuri

Shared biophysical mechanisms determine early biofilm architecture development across different bacterial species pp. 1-14

Hannah Jeckel, Francisco Díaz-Pascual, Dominic J Skinner, Boya Song, Eva Jiménez-Siebert, Kerstin Strenger, Eric Jelli, Sanika Vaidya, Jörn Dunkel and Knut Drescher

Differences in temporal processing speeds between the right and left auditory cortex reflect the strength of recurrent synaptic connectivity pp. 1-20

Demetrios Neophytou, Diego M Arribas, Tushar Arora, Robert B Levy, Il Memming Park and Hysell V Oviedo

Volume 20, issue 9, 2022

Strong evidence for the adaptive walk model of gene evolution in Drosophila and Arabidopsis pp. 1-26

Ana Filipa Moutinho, Adam Eyre-Walker and Julien Y Dutheil

A prosthesis utilizing natural vestibular encoding strategies improves sensorimotor performance in monkeys pp. 1-26

Kantapon Pum Wiboonsaksakul, Dale C Roberts, Charles C Della Santina and Kathleen E Cullen

Impact of gender on the formation and outcome of formal mentoring relationships in the life sciences pp. 1-24

Leah P Schwartz, Jean F Liénard and Stephen V David

Volume 20, issue 8, 2022

Multivariate phenotype analysis enables genome-wide inference of mammalian gene function pp. 1-41

George Nicholson, Hugh Morgan, Habib Ganjgahi, Steve D M Brown, Ann-Marie Mallon and Chris Holmes

Comprehensive analysis of locomotion dynamics in the protochordate Ciona intestinalis reveals how neuromodulators flexibly shape its behavioral repertoire pp. 1-44

Athira Athira, Daniel Dondorp, Jerneja Rudolf, Olivia Peytral and Marios Chatzigeorgiou

Volume 20, issue 7, 2022

Reptile research shows new avenues and old challenges for extinction risk modelling pp. 1-5

Moreno Di Marco

Johann Gregor Mendel: Born to be a scientist? pp. 1-3

Eva Matalova

Recommendations for empowering early career researchers to improve research culture and practice pp. 1-19

Brianne A Kent, Constance Holman, Emmanuella Amoako, Alberto Antonietti, James M Azam, Hanne Ballhausen, Yaw Bediako, Anat M Belasen, Clarissa F D Carneiro, Yen-Chung Chen, Ewoud B Compeer, Chelsea A C Connor, Sophia Crüwell, Humberto Debat, Emma Dorris, Hedyeh Ebrahimi, Jeffrey C Erlich, Florencia Fernández-Chiappe, Felix Fischer, Małgorzata Anna Gazda, Toivo Glatz, Peter Grabitz, Verena Heise, David G Kent, Hung Lo, Gary McDowell, Devang Mehta, Wolf-Julian Neumann, Kleber Neves, Mark Patterson, Naomi C Penfold, Sophie K Piper, Iratxe Puebla, Peter K Quashie, Carolina Paz Quezada, Julia L Riley, Jessica L Rohmann, Shyam Saladi, Benjamin Schwessinger, Bob Siegerink, Paulina Stehlik, Alexandra Tzilivaki, Kate D L Umbers, Aalok Varma, Kaivalya Walavalkar, Charlotte M de Winde, Cecilia Zaza and Tracey L Weissgerber

LiCl-induced sickness modulates rat gustatory cortical responses pp. 1-26

Bradly T Stone, Jian-You Lin, Abuzar Mahmood, Alden J Sanford and Donald B Katz

Estimating the transfer rates of bacterial plasmids with an adapted Luria–Delbrück fluctuation analysis pp. 1-23

Olivia Kosterlitz, Adamaris Muñiz Tirado, Claire Wate, Clint Elg, Ivana Bozic, Eva M Top and Benjamin Kerr

Volume 20, issue 6, 2022

The machine learning–powered BirdNET App reduces barriers to global bird research by enabling citizen science participation pp. 1-6

Connor M Wood, Stefan Kahl, Ashakur Rahaman and Holger Klinck

Volume 20, issue 5, 2022

Automated assessment reveals that the extinction risk of reptiles is widely underestimated across space and phylogeny pp. 1-24

Gabriel Henrique de Oliveira Caetano, David G Chapple, Richard Grenyer, Tal Raz, Jonathan Rosenblatt, Reid Tingley, Monika Böhm, Shai Meiri and Uri Roll

Bypassing shortages of personal protective equipment in low-income settings using local production and open source tools pp. 1-5

Royhaan Olamide Folarin, Mahmoud Bukar Maina, Abisola Kaosara Akinbo, Tamramat Iyabo Runsewe-Abiodun, Omobola Abioye Ogundahunsi, Ahmed Adebowale Adedeji and Andre Maia Chagas

Do multiple experimenters improve the reproducibility of animal studies? pp. 1-21

Vanessa Tabea von Kortzfleisch, Oliver Ambrée, Natasha A Karp, Neele Meyer, Janja Novak, Rupert Palme, Marianna Rosso, Chadi Touma, Hanno Würbel, Sylvia Kaiser, Norbert Sachser and S Helene Richter

Whole-proteome structures shed new light on posttranslational modifications pp. 1-3

Robbie P Joosten and Jon Agirre

Reestablishment of spermatogenesis after more than 20 years of cryopreservation of rat spermatogonial stem cells reveals an important impact in differentiation capacity pp. 1-23

Eoin C Whelan, Fan Yang, Mary R Avarbock, Megan C Sullivan, Daniel P Beiting and Ralph L Brinster

Recommendations for improving statistical inference in population genomics pp. 1-23

Parul Johri, Charles F Aquadro, Mark Beaumont, Brian Charlesworth, Laurent Excoffier, Adam Eyre-Walker, Peter D Keightley, Michael Lynch, Gil McVean, Bret A Payseur, Susanne P Pfeifer, Wolfgang Stephan and Jeffrey D Jensen

Neural networks enable efficient and accurate simulation-based inference of evolutionary parameters from adaptation dynamics pp. 1-32

Grace Avecilla, Julie N Chuong, Fangfei Li, Gavin Sherlock, David Gresham and Yoav Ram

Temporal analysis of melanogenesis identifies fatty acid metabolism as key skin pigment regulator pp. 1-32

Farina Sultan, Reelina Basu, Divya Murthy, Manisha Kochar, Kuldeep S Attri, Ayush Aggarwal, Pooja Kumari, Pooja Dnyane, Jyoti Tanwar, Rajender K Motiani, Archana Singh, Chetan Gadgil, Neel Sarovar Bhavesh, Pankaj K Singh, Vivek T Natarajan and Rajesh S Gokhale

Volume 20, issue 4, 2022

Erebosis, a new cell death mechanism during homeostatic turnover of gut enterocytes pp. 1-21

Hanna M Ciesielski, Hiroshi Nishida, Tomomi Takano, Aya Fukuhara, Tetsuhisa Otani, Yuko Ikegawa, Morihiro Okada, Takashi Nishimura, Mikio Furuse and Sa Kan Yoo

Population heterogeneity in clinical cohorts affects the predictive accuracy of brain imaging pp. 1-39

Oualid Benkarim, Casey Paquola, Bo-yong Park, Valeria Kebets, Seok-Jun Hong, Reinder Vos de Wael, Shaoshi Zhang, B T Thomas Yeo, Michael Eickenberg, Tian Ge, Jean-Baptiste Poline, Boris C Bernhardt and Danilo Bzdok

Volume 20, issue 3, 2022

Systematically assessing microbiome–disease associations identifies drivers of inconsistency in metagenomic research pp. 1-18

Braden T Tierney, Yingxuan Tan, Zhen Yang, Bing Shui, Michaela J Walker, Benjamin M Kent, Aleksandar D Kostic and Chirag J Patel

Correction of scientific literature: Too little, too late! pp. 1-4

Lonni Besançon, Elisabeth Bik, James Heathers and Gideon Meyerowitz-Katz

The effect of apathy and compulsivity on planning and stopping in sequential decision-making pp. 1-38

Jacqueline Scholl, Hailey A Trier, Matthew F S Rushworth and Nils Kolling

Cortical softening elicits zygotic contractility during mouse preimplantation development pp. 1-23

Özge Özgüç, Ludmilla de Plater, Varun Kapoor, Anna Francesca Tortorelli, Andrew G Clark and Jean-Léon Maître

Volume 20, issue 2, 2022

Meta-analysis reveals an extreme “decline effect” in the impacts of ocean acidification on fish behavior pp. 1-20

Jeff C Clements, Josefin Sundin, Timothy D Clark and Fredrik Jutfelt

Examining linguistic shifts between preprints and publications pp. 1-22

David N Nicholson, Vincent Rubinetti, Dongbo Hu, Marvin Thielk, Lawrence E Hunter and Casey S Greene

Analysis of 567,758 randomized controlled trials published over 30 years reveals trends in phrases used to discuss results that do not reach statistical significance pp. 1-15

Willem M Otte, Christiaan H Vinkers, Philippe C Habets, David G P van IJzendoorn and Joeri K Tijdink

People’s desire to be in nature and how they experience it are partially heritable pp. 1-16

Chia-chen Chang, Daniel T C Cox, Qiao Fan, Thi Phuong Le Nghiem, Claudia L Y Tan, Rachel Rui Ying Oh, Brenda B Lin, Danielle F Shanahan, Richard A Fuller, Kevin J Gaston and L. Roman Carrasco

SARS-CoV-2 antibodies protect against reinfection for at least 6 months in a multicentre seroepidemiological workplace cohort pp. 1-11

Emilie Finch, Rachel Lowe, Stephanie Fischinger, Michael de St Aubin, Sameed M Siddiqui, Diana Dayal, Michael A Loesche, Justin Rhee, Samuel Beger, Yiyuan Hu, Matthew J Gluck, Benjamin Mormann, Mohammad A Hasdianda, Elon R Musk, Galit Alter, Anil S Menon, Eric J Nilles, Adam J Kucharski and on behalf of the CMMID COVID-19 working group and the SpaceX COVID-19 Cohort Collaborative

Volume 20, issue 1, 2022

The first six years of meta-research at PLOS Biology pp. 1-4

Roland G Roberts and on behalf of the PLOS Biology Staff Editors

Endogenously produced catecholamines improve the regulatory function of TLR9-activated B cells pp. 1-30

Nadine Honke, Torsten Lowin, Birgit Opgenoorth, Namir Shaabani, Alexander Lautwein, John R Teijaro, Matthias Schneider and Georg Pongratz

Volume 19, issue 12, 2021

Noise-trained deep neural networks effectively predict human vision and its neural responses to challenging images pp. 1-27

Hojin Jang, Devin McCormack and Frank Tong

Poststroke dendritic arbor regrowth requires the actin nucleator Cobl pp. 1-35

Yuanyuan Ji, Dennis Koch, Jule González Delgado, Madlen Günther, Otto W Witte, Michael M Kessels, Christiane Frahm and Britta Qualmann

Comment on “Indirect Fitness Benefits Enable the Spread of Host Genes Promoting Costly Transfer of Beneficial Plasmids” pp. 1-5

Alastair Jamieson-Lane and Bernd Blasius

Genome-wide gene expression noise in Escherichia coli is condition-dependent and determined by propagation of noise through the regulatory network pp. 1-22

Arantxa Urchueguía, Luca Galbusera, Dany Chauvin, Gwendoline Bellement, Thomas Julou and Erik van Nimwegen

Noise increases the correspondence between artificial and human vision pp. 1-4

Jessica A F Thompson

Volume 19, issue 11, 2021

From grassroots to global: A blueprint for building a reproducibility network pp. 1-6

Reproducibility Network Steering Committee Uk

The economics of managing evolution pp. 1-14

Troy Day, David A Kennedy, Andrew F Read and David McAdams

NAMPT-derived NAD+ fuels PARP1 to promote skin inflammation through parthanatos cell death pp. 1-27

Francisco J Martínez-Morcillo, Joaquín Cantón-Sandoval, Francisco J Martínez-Navarro, Isabel Cabas, Idoya Martínez-Vicente, Joy Armistead, Julia Hatzold, Azucena López-Muñoz, Teresa Martínez-Menchón, Raúl Corbalán-Vélez, Jesús Lacal, Matthias Hammerschmidt, José C García-Borrón, Alfonsa García-Ayala, María L Cayuela, Ana B Pérez-Oliva, Diana García-Moreno and Victoriano Mulero

iSDAsoil: The first continent-scale soil property map at 30 m resolution provides a soil information revolution for Africa pp. 1-4

Matthew A E Miller, Keith D Shepherd, Bruce Kisitu and Jamie Collinson

A cloud-based toolbox for the versatile environmental annotation of biodiversity data pp. 1-22

Richard Li, Ajay Ranipeta, John Wilshire, Jeremy Malczyk, Michelle Duong, Robert Guralnick, Adam Wilson and Walter Jetz

A survey of biomedical journals to detect editorial bias and nepotistic behavior pp. 1-18

Alexandre Scanff, Florian Naudet, Ioana A Cristea, David Moher, Dorothy V M Bishop and Clara Locher

Volume 19, issue 10, 2021

A phylogenomic framework for charting the diversity and evolution of giant viruses pp. 1-18

Frank O Aylward, Mohammad Moniruzzaman, Anh D Ha and Eugene V Koonin

Deep learning allows genome-scale prediction of Michaelis constants from structural features pp. 1-21

Alexander Kroll, Martin K M Engqvist, David Heckmann and Martin J Lercher

A field guide to cultivating computational biology pp. 1-14

Gregory P Way, Casey S Greene, Piero Carninci, Benilton S Carvalho, Michiel de Hoon, Stacey D Finley, Sara J C Gosline, Kim-Anh Lȇ Cao, Jerry S H Lee, Luigi Marchionni, Nicolas Robine, Suzanne S Sindi, Fabian J Theis, Jean Y H Yang, Anne E Carpenter and Elana J Fertig

Volume 19, issue 9, 2021

A 3-year evaluation of preclinicaltrials.eu reveals room for improvement in preregistration of animal studies pp. 1-5

Mira van der Naald, Steven A J Chamuleau, Julia M L Menon, Wim de Leeuw, Judith J de Haan, Dirk J Duncker and Kimberley E Wever

Microplastics and anthropogenic fibre concentrations in lakes reflect surrounding land use pp. 1-18

Andrew J Tanentzap, Samuel Cottingham, Jérémy Fonvielle, Isobel Riley, Lucy M Walker, Samuel G Woodman, Danai Kontou, Christian M Pichler, Erwin Reisner and Laurent Lebreton

Twenty steps to ingrain power asymmetry in global health biomedical research pp. 1-4

Iruka N Okeke

Cooperating elephants mitigate competition until the stakes get too high pp. 1-23

Li-Li Li, Joshua M Plotnik, Shang-Wen Xia, Estelle Meaux and Rui-Chang Quan

Stimulation of the left dorsolateral prefrontal cortex with slow rTMS enhances verbal memory formation pp. 1-21

Mircea van der Plas, Verena Braun, Benjamin Johannes Stauch and Simon Hanslmayr

Volume 19, issue 8, 2021

Challenges in interpreting cytokine data in COVID-19 affect patient care and management pp. 1-5

Stephen Y Wang, Takehiro Takahashi, Alexander B Pine, William E Damsky, Michael Simonov, Yanhua Zhang, Elizabeth Kieras, Christina C Price, Brett A King, Mark D Siegel, Gary V Desir, Alfred I Lee, Akiko Iwasaki and Hyung J Chun

A flexible framework for multi-particle refinement in cryo-electron tomography pp. 1-16

Alister Burt, Lorenzo Gaifas, Tom Dendooven and Irina Gutsche

Conjunctive spatial and self-motion codes are topographically organized in the GABAergic cells of the lateral septum pp. 1-36

Suzanne van der Veldt, Guillaume Etter, Coralie-Anne Mosser, Frédéric Manseau and Sylvain Williams

Response to “Vast (but avoidable) underestimation of global biodiversity” pp. 1-4

Stilianos Louca, Florent Mazel, Michael Doebeli and Laura Wegener Parfrey

Volume 19, issue 7, 2021

Don’t let the perfect be the enemy of the good pp. 1-3

Marcus Munafò

Learning from the past to develop data analysis curricula for the future pp. 1-3

Tracey L Weissgerber

A cross-institutional analysis of the effects of broadening trainee professional development on research productivity pp. 1-21

Patrick D Brandt, Susi Sturzenegger Varvayanis, Tracey Baas, Amanda F Bolgioni, Janet Alder, Kimberly A Petrie, Isabel Dominguez, Abigail M Brown, C Abigail Stayart, Harinder Singh, Audra Van Wart, Christine S Chow, Ambika Mathur, Barbara M Schreiber, David A Fruman, Brent Bowden, Christopher A Wiesen, Yvonne M Golightly, Chris E Holmquist, Daniel Arneman, Joshua D Hall, Linda E Hyman, Kathleen L Gould, Roger Chalkley, Patrick J Brennwald and Rebekah L Layton

Viral dynamics of acute SARS-CoV-2 infection and applications to diagnostic and public health strategies pp. 1-17

Stephen M Kissler, Joseph R Fauver, Christina Mack, Scott W Olesen, Caroline Tai, Kristin Y Shiue, Chaney C Kalinich, Sarah Jednak, Isabel M Ott, Chantal B F Vogels, Jay Wohlgemuth, James Weisberger, John DiFiori, Deverick J Anderson, Jimmie Mancell, David D Ho, Nathan D Grubaugh and Yonatan H Grad

Educating the future generation of researchers: A cross-disciplinary survey of trends in analysis methods pp. 1-23

Taylor Bolt, Jason S Nomi, Danilo Bzdok and Lucina Q Uddin

IVEN: A quantitative tool to describe 3D cell position and neighbourhood reveals architectural changes in FGF4-treated preimplantation embryos pp. 1-25

Jessica E Forsyth, Ali H Al-Anbaki, Roberto de la Fuente, Nikkinder Modare, Diego Perez-Cortes, Isabel Rivera, Rowena Seaton Kelly, Simon Cotter and Berenika Plusa

Heteroresistance to beta-lactam antibiotics may often be a stage in the progression to antibiotic resistance pp. 1-8

Victor I Band and David S Weiss

Assessing the replicability of spatial gene expression using atlas data from the adult mouse brain pp. 1-27

Shaina Lu, Cantin Ortiz, Daniel Fürth, Stephan Fischer, Konstantinos Meletis, Anthony Zador and Jesse Gillis

Volume 19, issue 6, 2021

Intrinsic connectivity reveals functionally distinct cortico-hippocampal networks in the human brain pp. 1-34

Alexander J Barnett, Walter Reilly, Halle R Dimsdale-Zucker, Eda Mizrak, Zachariah Reagh and Charan Ranganath

Atypical and inflexible visual encoding in autism spectrum disorder pp. 1-5

Emily L Isenstein, Woon Ju Park and Duje Tadin

Promoting inclusive metrics of success and impact to dismantle a discriminatory reward system in science pp. 1-15

Sarah W Davies, Hollie M Putnam, Tracy Ainsworth, Julia K Baum, Colleen B Bove, Sarah C Crosby, Isabelle M Côté, Anne Duplouy, Robinson W Fulweiler, Alyssa J Griffin, Torrance C Hanley, Tessa Hill, Adriana Humanes, Sangeeta Mangubhai, Anna Metaxas, Laura M Parker, Hanny E Rivera, Nyssa J Silbiger, Nicola S Smith, Ana K Spalding, Nikki Traylor-Knowles, Brooke L Weigel, Rachel M Wright and Amanda E Bates

Volume 19, issue 5, 2021

A generation of junior faculty is at risk from the impacts of COVID-19 pp. 1-3

Tiffany M Lowe-Power, Louise Dyson and Abigail M Polter

Extracellular DJ-1 induces sterile inflammation in the ischemic brain pp. 1-21

Koutarou Nakamura, Seiichiro Sakai, Jun Tsuyama, Akari Nakamura, Kento Otani, Kumiko Kurabayashi, Yoshiko Yogiashi, Hisao Masai and Takashi Shichita

Individuals with autism spectrum disorder have altered visual encoding capacity pp. 1-21

Jean-Paul Noel, Ling-Qi Zhang, Alan A Stocker and Dora E Angelaki

Epidemiology and reporting characteristics of preclinical systematic reviews pp. 1-17

Victoria T Hunniford, Joshua Montroy, Dean A Fergusson, Marc T Avey, Kimberley E Wever, Sarah K McCann, Madison Foster, Grace Fox, Mackenzie Lafreniere, Mira Ghaly, Sydney Mannell, Karolina Godwinska, Avonae Gentles, Shehab Selim, Jenna MacNeil, Lindsey Sikora, Emily S Sena, Matthew J Page, Malcolm Macleod, David Moher and Manoj M Lalu

Meta-analysis of variation suggests that embracing variability improves both replicability and generalizability in preclinical research pp. 1-20

Takuji Usui, Malcolm R Macleod, Sarah K McCann, Alistair M Senior and Shinichi Nakagawa

Neural oscillations are a start toward understanding brain activity rather than the end pp. 1-12

Keith B Doelling and M Florencia Assaneo

Cell-level metadata are indispensable for documenting single-cell sequencing datasets pp. 1-10

Sidhant Puntambekar, Jay R Hesselberth, Kent A Riemondy and Rui Fu

Volume 19, issue 4, 2021

Farnesyl pyrophosphate is a new danger signal inducing acute cell death pp. 1-25

Jing Chen, Xiaochen Zhang, Liping Li, Xianqiang Ma, Chunxiao Yang, Zhaodi Liu, Chenyang Li, Maria J Fernandez-Cabezudo, Basel K al-Ramadi, Chuan Wu, Weishan Huang, Yong Zhang, Yonghui Zhang and Wanli Liu

Quantitative proteome comparison of human hearts with those of model organisms pp. 1-22

Nora Linscheid, Alberto Santos, Pi Camilla Poulsen, Robert W Mills, Kirstine Calloe, Ulrike Leurs, Johan Z Ye, Christian Stolte, Morten B Thomsen, Bo H Bentzen, Pia R Lundegaard, Morten S Olesen, Lars J Jensen, Jesper V Olsen and Alicia Lundby

Volume 19, issue 3, 2021

Towards precision medicine in diabetes? A critical review of glucotypes pp. 1-5

Adam Hulman, Yuri D Foreman, Martijn C G J Brouwers, Abraham A Kroon, Koen D Reesink, Pieter C Dagnelie, Carla J H van der Kallen, Marleen M J van Greevenbroek, Kristine Færch, Dorte Vistisen, Marit E Jørgensen, Coen D A Stehouwer and Daniel R Witte

Response to Hulman and colleagues regarding “Glucotypes reveal new patterns of glucose dysregulation” pp. 1-4

Alessandra Breschi, Dalia Perelman and Michael Paul Snyder

Visible name changes promote inequity for transgender researchers pp. 1-4

Leo Chan Gaskins and Craig R McClain

How PLOS Biology aims to foster diversity, equity and inclusion in science pp. 1-3

The PLOS Biology Staff Editors

Is “bioinformatics” dead? pp. 1-3

Philip E Bourne

Rebuild the Academy: Supporting academic mothers during COVID-19 and beyond pp. 1-11

Robinson W Fulweiler, Sarah W Davies, Jennifer F Biddle, Amy J Burgin, Emily H G Cooperdock, Torrance C Hanley, Carly D Kenkel, Amy M Marcarelli, Catherine M Matassa, Talea L Mayo, Lory Z Santiago-Vàzquez, Nikki Traylor-Knowles and Maren Ziegler

From Reductionism to Reintegration: Solving society’s most pressing problems requires building bridges between data types across the life sciences pp. 1-12

Anne E Thessen, Paul Bogdan, David J Patterson, Theresa M Casey, César Hinojo-Hinojo, Orlando de Lange and Melissa A Haendel

Assessment of transparency indicators across the biomedical literature: How open is open? pp. 1-26

Stylianos Serghiou, Despina G Contopoulos-Ioannidis, Kevin W Boyack, Nico Riedel, Joshua D Wallach and John P A Ioannidis

Reexposure to a sensorimotor perturbation produces opposite effects on explicit and implicit learning processes pp. 1-26

Guy Avraham, J Ryan Morehead, Hyosub E Kim and Richard B Ivry

Volume 19, issue 2, 2021

Training early career researchers to use meta-research to improve science: A participant-guided “learn by doing” approach pp. 1-5

Tracey L Weissgerber

Sustained neural rhythms reveal endogenous oscillations supporting speech perception pp. 1-33

Sander van Bree, Ediz Sohoglu, Matthew H Davis and Benedikt Zoefel

Volume 19, issue 1, 2021

Ectoderm to mesoderm transition by down-regulation of actomyosin contractility pp. 1-33

Leily Kashkooli, David Rozema, Lina Espejo-Ramirez, Paul Lasko and François Fagotto