PLOS Computational Biology

2005 - 2025

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Transcriptional Regulation by Competing Transcription Factor Modules pp. 1-9: Rutger Hermsen, Sander Tans and Pieter Rein ten Wolde
Cooperation is Fleeting in the World of Transposable Elements pp. 1-8: Andreas Wagner
Gene Expression of Caenorhabditis elegans Neurons Carries Information on Their Synaptic Connectivity pp. 1-7: Alon Kaufman, Gideon Dror, Isaac Meilijson and Eytan Ruppin

Funneled Landscape Leads to Robustness of Cell Networks: Yeast Cell Cycle pp. 1-10: Jin Wang, Bo Huang, Xuefeng Xia and Zhirong Sun
Ten Simple Rules for Selecting a Postdoctoral Position pp. 1-2: Philip E Bourne and Iddo Friedberg
Computational Inference of Neural Information Flow Networks pp. 1-14: V Anne Smith, Jing Yu, Tom V Smulders, Alexander J Hartemink and Erich D Jarvis
Optimal Noise Filtering in the Chemotactic Response of Escherichia coli pp. 1-12: Burton W Andrews, Tau-Mu Yi and Pablo A Iglesias
Meta-Analysis of Differentiating Mouse Embryonic Stem Cell Gene Expression Kinetics Reveals Early Change of a Small Gene Set pp. 1-12: Clive H Glover, Michael Marin, Connie J Eaves, Cheryl D Helgason, James M Piret and Jennifer Bryan
Robustness and Fragility in Immunosenescence pp. 1-7: Sean P Stromberg and Jean Carlson
Humans Can Adopt Optimal Discounting Strategy under Real-Time Constraints pp. 1-8: N Schweighofer, K Shishida, C E Han, Y Okamoto, S C Tanaka, S Yamawaki and K Doya

Cooperation Prevails When Individuals Adjust Their Social Ties pp. 1-8: Francisco C Santos, Jorge M Pacheco and Tom Lenaerts

Sampling Realistic Protein Conformations Using Local Structural Bias pp. 1-13: Thomas Hamelryck, John T Kent and Anders Krogh
Ten Simple Rules for Reviewers pp. 1-2: Philip E Bourne and Alon Korngreen
Imitating Manual Curation of Text-Mined Facts in Biomedicine pp. 1-14: Raul Rodriguez-Esteban, Ivan Iossifov and Andrey Rzhetsky

The Ion Channel Inverse Problem: Neuroinformatics Meets Biophysics pp. 1-8: Robert C Cannon and Giampaolo D'Alessandro
Insights into the Coupling of Duplication Events and Macroevolution from an Age Profile of Animal Transmembrane Gene Families pp. 1-7: Guohui Ding, Jiuhong Kang, Qi Liu, Tieliu Shi, Gang Pei and Yixue Li

Wiggle—Predicting Functionally Flexible Regions from Primary Sequence pp. 1-17: Jenny Gu, Michael Gribskov and Philip E Bourne
Identification of Genome-Scale Metabolic Network Models Using Experimentally Measured Flux Profiles pp. 1-11: Markus J Herrgård, Stephen S Fong and Bernhard Ø Palsson
Complex Parameter Landscape for a Complex Neuron Model pp. 1-11: Pablo Achard and Erik De Schutter
Nonoptimal Component Placement, but Short Processing Paths, due to Long-Distance Projections in Neural Systems pp. 1-11: Marcus Kaiser and Claus C Hilgetag
Authors' Reply pp. 1-2: Hung D Nguyen, Maki Yoshihama and Naoya Kenmochi
On the Estimation of Intron Evolution pp. 1-1: Miklós Csűrös

Inferring Loss-of-Heterozygosity from Unpaired Tumors Using High-Density Oligonucleotide SNP Arrays pp. 1-10: Rameen Beroukhim, Ming Lin, Yuhyun Park, Ke Hao, Xiaojun Zhao, Levi A Garraway, Edward A Fox, Ephraim P Hochberg, Ingo K Mellinghoff, Matthias D Hofer, Aurelien Descazeaud, Mark A Rubin, Matthew Meyerson, Wing Hung Wong, William R Sellers and Cheng Li
Iterative Reconstruction of Transcriptional Regulatory Networks: An Algorithmic Approach pp. 1-10: Christian L Barrett and Bernhard O Palsson
Reverse Engineering the Gap Gene Network of Drosophila melanogaster pp. 1-12: Theodore J Perkins, Johannes Jaeger, John Reinitz and Leon Glass

Codon Usage Domains over Bacterial Chromosomes pp. 1-13: Marc Bailly-Bechet, Antoine Danchin, Mudassar Iqbal, Matteo Marsili and Massimo Vergassola

Ten Simple Rules for Getting Grants pp. 1-2: Philip E Bourne and Leo M Chalupa

Bioinformatics Education—Perspectives and Challenges pp. 1-2: Shoba Ranganathan
A Guild of 45 CRISPR-Associated (Cas) Protein Families and Multiple CRISPR/Cas Subtypes Exist in Prokaryotic Genomes pp. 1-10: Daniel H Haft, Jeremy Selengut, Emmanuel F Mongodin and Karen E Nelson

Protein Molecular Function Prediction by Bayesian Phylogenomics pp. 1-: Barbara E Engelhardt, Michael I Jordan, Kathryn E Muratore and Steven E Brenner
Ten Simple Rules for Getting Published pp. 1-2: Philip E Bourne