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PLOS Computational Biology

2005 - 2025

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Volume 8, issue 12, 2012

Molecular Evolution of Peptide Ligands with Custom-Tailored Characteristics for Targeting of Glycostructures pp. 1-10 Downloads
Niels Röckendorf, Markus Borschbach and Andreas Frey
Reliable B Cell Epitope Predictions: Impacts of Method Development and Improved Benchmarking pp. 1-10 Downloads
Jens Vindahl Kringelum, Claus Lundegaard, Ole Lund and Morten Nielsen
ACME: Automated Cell Morphology Extractor for Comprehensive Reconstruction of Cell Membranes pp. 1-14 Downloads
Kishore R Mosaliganti, Ramil R Noche, Fengzhu Xiong, Ian A Swinburne and Sean G Megason
SnIPRE: Selection Inference Using a Poisson Random Effects Model pp. 1-14 Downloads
Kirsten E Eilertson, James G Booth and Carlos D Bustamante
Parameter Identifiability and Sensitivity Analysis Predict Targets for Enhancement of STAT1 Activity in Pancreatic Cancer and Stellate Cells pp. 1-14 Downloads
Katja Rateitschak, Felix Winter, Falko Lange, Robert Jaster and Olaf Wolkenhauer
A Comparison of Computational Models for Eukaryotic Cell Shape and Motility pp. 1-17 Downloads
William R Holmes and Leah Edelstein-Keshet
Chapter 10: Mining Genome-Wide Genetic Markers pp. 1-9 Downloads
Xiang Zhang, Shunping Huang, Zhaojun Zhang and Wei Wang
Computational Phenotyping of Two-Person Interactions Reveals Differential Neural Response to Depth-of-Thought pp. 1-9 Downloads
Ting Xiang, Debajyoti Ray, Terry Lohrenz, Peter Dayan and P Read Montague
Chapter 2: Data-Driven View of Disease Biology pp. 1-8 Downloads
Casey S Greene and Olga G Troyanskaya
Chapter 13: Mining Electronic Health Records in the Genomics Era pp. 1-15 Downloads
Joshua C Denny
Chapter 9: Analyses Using Disease Ontologies pp. 1-12 Downloads
Nigam H Shah, Tyler Cole and Mark A Musen
Chapter 8: Biological Knowledge Assembly and Interpretation pp. 1-12 Downloads
Ju Han Kim
Novel Modeling of Combinatorial miRNA Targeting Identifies SNP with Potential Role in Bone Density pp. 1-13 Downloads
Claudia Coronnello, Ryan Hartmaier, Arshi Arora, Luai Huleihel, Kusum V Pandit, Abha S Bais, Michael Butterworth, Naftali Kaminski, Gary D Stormo, Steffi Oesterreich and Panayiotis V Benos

Volume 8, issue 11, 2012

Strategy Diversity Stabilizes Mutualism through Investment Cycles, Phase Polymorphism, and Spatial Bubbles pp. 1-14 Downloads
Gergely Boza, Ádám Kun, István Scheuring and Ulf Dieckmann
A Bayesian Inference Framework to Reconstruct Transmission Trees Using Epidemiological and Genetic Data pp. 1-14 Downloads
Marco J Morelli, Gaël Thébaud, Joël Chadœuf, Donald P King, Daniel T Haydon and Samuel Soubeyrand
Stochastic Modeling of Expression Kinetics Identifies Messenger Half-Lives and Reveals Sequential Waves of Co-ordinated Transcription and Decay pp. 1-14 Downloads
Filippo Cacace, Paola Paci, Valerio Cusimano, Alfredo Germani and Lorenzo Farina
Functional Inference of Complex Anatomical Tendinous Networks at a Macroscopic Scale via Sparse Experimentation pp. 1-17 Downloads
Anupam Saxena, Hod Lipson and Francisco J Valero-Cuevas
Mesoscopic Model of Actin-Based Propulsion pp. 1-12 Downloads
Jie Zhu and Alex Mogilner
A Graphical Modelling Approach to the Dissection of Highly Correlated Transcription Factor Binding Site Profiles pp. 1-13 Downloads
Robert Stojnic, Audrey Qiuyan Fu and Boris Adryan
Chemotactic Migration of T Cells towards Dendritic Cells Promotes the Detection of Rare Antigens pp. 1-13 Downloads
Renske M A Vroomans, Athanasius F M Marée, Rob J de Boer and Joost B Beltman
Coordinated Optimization of Visual Cortical Maps (II) Numerical Studies pp. 1-26 Downloads
Lars Reichl, Dominik Heide, Siegrid Löwel, Justin C Crowley, Matthias Kaschube and Fred Wolf
Coordinated Optimization of Visual Cortical Maps (I) Symmetry-based Analysis pp. 1-24 Downloads
Lars Reichl, Dominik Heide, Siegrid Löwel, Justin C Crowley, Matthias Kaschube and Fred Wolf
Internal Representations of Temporal Statistics and Feedback Calibrate Motor-Sensory Interval Timing pp. 1-19 Downloads
Luigi Acerbi, Daniel M Wolpert and Sethu Vijayakumar
How Random Is Social Behaviour? Disentangling Social Complexity through the Study of a Wild House Mouse Population pp. 1-11 Downloads
Nicolas Perony, Claudio J Tessone, Barbara König and Frank Schweitzer
Reconstructing Mammalian Sleep Dynamics with Data Assimilation pp. 1-15 Downloads
Madineh Sedigh-Sarvestani, Steven J Schiff and Bruce J Gluckman
Ten Simple Rules to Protect Your Intellectual Property pp. 1-4 Downloads
Mark Jolly, Anthony C Fletcher and Philip E Bourne

Volume 8, issue 10, 2012

A Model of Reward- and Effort-Based Optimal Decision Making and Motor Control pp. 1-13 Downloads
Lionel Rigoux and Emmanuel Guigon
Analysis of Slow (Theta) Oscillations as a Potential Temporal Reference Frame for Information Coding in Sensory Cortices pp. 1-13 Downloads
Christoph Kayser, Robin A A Ince and Stefano Panzeri
Evaluating the Adequacy of Gravity Models as a Description of Human Mobility for Epidemic Modelling pp. 1-12 Downloads
James Truscott and Neil M Ferguson
CAVER 3.0: A Tool for the Analysis of Transport Pathways in Dynamic Protein Structures pp. 1-12 Downloads
Eva Chovancova, Antonin Pavelka, Petr Benes, Ondrej Strnad, Jan Brezovsky, Barbora Kozlikova, Artur Gora, Vilem Sustr, Martin Klvana, Petr Medek, Lada Biedermannova, Jiri Sochor and Jiri Damborsky
Very Slow Search and Reach: Failure to Maximize Expected Gain in an Eye-Hand Coordination Task pp. 1-12 Downloads
Hang Zhang, Camille Morvan, Louis-Alexandre Etezad-Heydari and Laurence T Maloney
Predictive Dynamics of Human Pain Perception pp. 1-12 Downloads
Guillermo A Cecchi, Lejian Huang, Javeria Ali Hashmi, Marwan Baliki, María V Centeno, Irina Rish and A Vania Apkarian
Coding and Decoding with Adapting Neurons: A Population Approach to the Peri-Stimulus Time Histogram pp. 1-14 Downloads
Richard Naud and Wulfram Gerstner
Estimating the Hidden Burden of Bovine Tuberculosis in Great Britain pp. 1-14 Downloads
Andrew J K Conlan, Trevelyan J McKinley, Katerina Karolemeas, Ellen Brooks Pollock, Anthony V Goodchild, Andrew P Mitchell, Colin P D Birch, Richard S Clifton-Hadley and James L N Wood
Connecting Macroscopic Observables and Microscopic Assembly Events in Amyloid Formation Using Coarse Grained Simulations pp. 1-10 Downloads
Noah S Bieler, Tuomas P J Knowles, Daan Frenkel and Robert Vácha
Ubiquitin Dynamics in Complexes Reveal Molecular Recognition Mechanisms Beyond Induced Fit and Conformational Selection pp. 1-10 Downloads
Jan H Peters and Bert L de Groot
Probability Fluxes and Transition Paths in a Markovian Model Describing Complex Subunit Cooperativity in HCN2 Channels pp. 1-10 Downloads
Klaus Benndorf, Jana Kusch and Eckhard Schulz
How Recent History Affects Perception: The Normative Approach and Its Heuristic Approximation pp. 1-10 Downloads
Ofri Raviv, Merav Ahissar and Yonatan Loewenstein
Seven Years; It's Time for a Change pp. 1-2 Downloads
Philip E Bourne
Spatially Pooled Contrast Responses Predict Neural and Perceptual Similarity of Naturalistic Image Categories pp. 1-16 Downloads
Iris I A Groen, Sennay Ghebreab, Victor A F Lamme and H Steven Scholte

Volume 8, issue 9, 2012

Evolutionary Dynamics on Protein Bi-stability Landscapes can Potentially Resolve Adaptive Conflicts pp. 1-17 Downloads
Tobias Sikosek, Erich Bornberg-Bauer and Hue Sun Chan
Substrate-Specific Reorganization of the Conformational Ensemble of CSK Implicates Novel Modes of Kinase Function pp. 1-8 Downloads
Michael A Jamros, Leandro C Oliveira, Paul C Whitford, José N Onuchic, Joseph A Adams and Patricia A Jennings
Speeded Reaching Movements around Invisible Obstacles pp. 1-9 Downloads
Todd E Hudson, Uta Wolfe and Laurence T Maloney
Binding of Two Intrinsically Disordered Peptides to a Multi-Specific Protein: A Combined Monte Carlo and Molecular Dynamics Study pp. 1-9 Downloads
Iskra Staneva, Yongqi Huang, Zhirong Liu and Stefan Wallin
Risk-Sensitivity in Bayesian Sensorimotor Integration pp. 1-7 Downloads
Jordi Grau-Moya, Pedro A Ortega and Daniel A Braun
Correlated Electrostatic Mutations Provide a Reservoir of Stability in HIV Protease pp. 1-10 Downloads
Omar Haq, Michael Andrec, Alexandre V Morozov and Ronald M Levy
High-throughput Computer Method for 3D Neuronal Structure Reconstruction from the Image Stack of the Drosophila Brain and Its Applications pp. 1-12 Downloads
Ping-Chang Lee, Chao-Chun Chuang, Ann-Shyn Chiang and Yu-Tai Ching
Spike-based Decision Learning of Nash Equilibria in Two-Player Games pp. 1-12 Downloads
Johannes Friedrich and Walter Senn
Dependencies among Editing Sites in Serotonin 2C Receptor mRNA pp. 1-13 Downloads
Liran Carmel, Eugene V Koonin and Stella Dracheva
Spike-Timing Dependence of Structural Plasticity Explains Cooperative Synapse Formation in the Neocortex pp. 1-13 Downloads
Moritz Deger, Moritz Helias, Stefan Rotter and Markus Diesmann
Predicting the Extension of Biomedical Ontologies pp. 1-16 Downloads
Catia Pesquita and Francisco M Couto
Why Open Drug Discovery Needs Four Simple Rules for Licensing Data and Models pp. 1-3 Downloads
Antony J Williams, John Wilbanks and Sean Ekins
Ten Simple Rules To Commercialize Scientific Research pp. 1-3 Downloads
Anthony C Fletcher and Philip E Bourne

Volume 8, issue 8, 2012

Evolutionary Dynamics of Strategic Behavior in a Collective-Risk Dilemma pp. 1-7 Downloads
Maria Abou Chakra and Arne Traulsen
Hybrid Models and Biological Model Reduction with PyDSTool pp. 1-8 Downloads
Robert Clewley
A Topological Paradigm for Hippocampal Spatial Map Formation Using Persistent Homology pp. 1-14 Downloads
Y Dabaghian, F Mémoli, L Frank and G Carlsson
The Landscape of the Prion Protein's Structural Response to Mutation Revealed by Principal Component Analysis of Multiple NMR Ensembles pp. 1-14 Downloads
Deena M A Gendoo and Paul M Harrison
Locust Dynamics: Behavioral Phase Change and Swarming pp. 1-11 Downloads
Chad M Topaz, Maria R D'Orsogna, Leah Edelstein-Keshet and Andrew J Bernoff
Decorrelation of Neural-Network Activity by Inhibitory Feedback pp. 1-29 Downloads
Tom Tetzlaff, Moritz Helias, Gaute T Einevoll and Markus Diesmann
The Roots of Bioinformatics in ISMB pp. 1-10 Downloads
Todd A Gibson
Unifying Time to Contact Estimation and Collision Avoidance across Species pp. 1-1 Downloads
Matthias S Keil and Joan López-Moliner
Design and Implementation of a Genomics Field Trip Program Aimed at Secondary School Students pp. 1-1 Downloads
Jennifer McQueen, Jody J Wright and Joanne A Fox
A Network-based Approach for Predicting Missing Pathway Interactions pp. 1-13 Downloads
Saket Navlakha, Anthony Gitter and Ziv Bar-Joseph
Combining the Finite Element Method with Structural Connectome-based Analysis for Modeling Neurotrauma: Connectome Neurotrauma Mechanics pp. 1-15 Downloads
Reuben H Kraft, Phillip Justin Mckee, Amy M Dagro and Scott T Grafton

Volume 8, issue 7, 2012

Which of Our Modeling Predictions Are Robust? pp. 1-5 Downloads
Rob J De Boer
Coding Conspecific Identity and Motion in the Electric Sense pp. 1-16 Downloads
Na Yu, Ginette Hupé, Charles Garfinkle, John E Lewis and André Longtin
Efficiency and Power as a Function of Sequence Coverage, SNP Array Density, and Imputation pp. 1-13 Downloads
Jason Flannick, Joshua M Korn, Pierre Fontanillas, George B Grant, Eric Banks, Mark A Depristo and David Altshuler
Spectral Analysis of Input Spike Trains by Spike-Timing-Dependent Plasticity pp. 1-22 Downloads
Matthieu Gilson, Tomoki Fukai and Anthony N Burkitt
Genome-Wide Localization of Protein-DNA Binding and Histone Modification by a Bayesian Change-Point Method with ChIP-seq Data pp. 1-12 Downloads
Haipeng Xing, Yifan Mo, Will Liao and Michael Q Zhang
Assessing Drug Target Association Using Semantic Linked Data pp. 1-10 Downloads
Bin Chen, Ying Ding and David J Wild
A Preformed Binding Interface in the Unbound Ensemble of an Intrinsically Disordered Protein: Evidence from Molecular Simulations pp. 1-10 Downloads
Michael Knott and Robert B Best
Network-Assisted Investigation of Combined Causal Signals from Genome-Wide Association Studies in Schizophrenia pp. 1-11 Downloads
Peilin Jia, Lily Wang, Ayman H Fanous, Carlos N Pato, Todd L Edwards, The International Schizophrenia Consortium and Zhongming Zhao
Why SIT Works: Normal Function Despite Typical Myofiber Pattern in Situs Inversus Totalis (SIT) Hearts Derived by Shear-induced Myofiber Reorientation pp. 1-11 Downloads
Marieke Pluijmert, Wilco Kroon, Alessandro C Rossi, Peter H M Bovendeerd and Tammo Delhaas
Modular Design of Artificial Tissue Homeostasis: Robust Control through Synthetic Cellular Heterogeneity pp. 1-18 Downloads
Miles Miller, Marc Hafner, Eduardo Sontag, Noah Davidsohn, Sairam Subramanian, Priscilla E M Purnick, Douglas Lauffenburger and Ron Weiss
Automated Tracking of Whiskers in Videos of Head Fixed Rodents pp. 1-8 Downloads
Nathan G Clack, Daniel H O'Connor, Daniel Huber, Leopoldo Petreanu, Andrew Hires, Simon Peron, Karel Svoboda and Eugene W Myers

Volume 8, issue 6, 2012

MC EMiNEM Maps the Interaction Landscape of the Mediator pp. 1-10 Downloads
Theresa Niederberger, Stefanie Etzold, Michael Lidschreiber, Kerstin C Maier, Dietmar E Martin, Holger Fröhlich, Patrick Cramer and Achim Tresch
A Report of the Curriculum Task Force of the ISCB Education Committee pp. 1-2 Downloads
Lonnie R Welch, Russell Schwartz and Fran Lewitter
Charge Profile Analysis Reveals That Activation of Pro-apoptotic Regulators Bax and Bak Relies on Charge Transfer Mediated Allosteric Regulation pp. 1-11 Downloads
Crina-Maria Ionescu, Radka Svobodová Vařeková, Jochen H M Prehn, Heinrich J Huber and Jaroslav Koča
Short Term Synaptic Depression Imposes a Frequency Dependent Filter on Synaptic Information Transfer pp. 1-18 Downloads
Robert Rosenbaum, Jonathan Rubin and Brent Doiron
Deceleration of Fusion–Fission Cycles Improves Mitochondrial Quality Control during Aging pp. 1-18 Downloads
Marc Thilo Figge, Andreas S Reichert, Michael Meyer-Hermann and Heinz D Osiewacz
Modeling Boundary Vector Cell Firing Given Optic Flow as a Cue pp. 1-17 Downloads
Florian Raudies and Michael E Hasselmo
Fast Spatiotemporal Smoothing of Calcium Measurements in Dendritic Trees pp. 1-17 Downloads
Eftychios A Pnevmatikakis, Keith Kelleher, Rebecca Chen, Petter Saggau, Krešimir Josić and Liam Paninski
Protein Scaffolds Can Enhance the Bistability of Multisite Phosphorylation Systems pp. 1-9 Downloads
Carlo Chan, Xinfeng Liu, Liming Wang, Lee Bardwell, Qing Nie and Germán Enciso
A Model-Based Bayesian Estimation of the Rate of Evolution of VNTR Loci in Mycobacterium tuberculosis pp. 1-9 Downloads
R Zachariah Aandahl, Josephine F Reyes, Scott A Sisson and Mark M Tanaka
Fast Coding of Orientation in Primary Visual Cortex pp. 1-16 Downloads
Oren Shriki, Adam Kohn and Maoz Shamir
Posterior Association Networks and Functional Modules Inferred from Rich Phenotypes of Gene Perturbations pp. 1-16 Downloads
Xin Wang, Mauro A Castro, Klaas W Mulder and Florian Markowetz
The Role of Non-Native Interactions in the Folding of Knotted Proteins pp. 1-12 Downloads
Tatjana Škrbić, Cristian Micheletti and Pietro Faccioli
Structural Drift: The Population Dynamics of Sequential Learning pp. 1-12 Downloads
James P Crutchfield and Sean Whalen
A Maximum Entropy Test for Evaluating Higher-Order Correlations in Spike Counts pp. 1-12 Downloads
Arno Onken, Valentin Dragoi and Klaus Obermayer
A Scalable Algorithm to Explore the Gibbs Energy Landscape of Genome-Scale Metabolic Networks pp. 1-12 Downloads
Daniele De Martino, Matteo Figliuzzi, Andrea De Martino and Enzo Marinari

Volume 8, issue 5, 2012

A Spatial Model of Mosquito Host-Seeking Behavior pp. 1-13 Downloads
Bree Cummins, Ricardo Cortez, Ivo M Foppa, Justin Walbeck and James M Hyman
Optimality of Human Contour Integration pp. 1-17 Downloads
Udo A Ernst, Sunita Mandon, Nadja Schinkel–Bielefeld, Simon D Neitzel, Andreas K Kreiter and Klaus R Pawelzik
Crossing Over…Markov Meets Mendel pp. 1-12 Downloads
Saad Mneimneh
Exploring Massive, Genome Scale Datasets with the GenometriCorr Package pp. 1-12 Downloads
Alexander Favorov, Loris Mularoni, Leslie M Cope, Yulia Medvedeva, Andrey A Mironov, Vsevolod J Makeev and Sarah J Wheelan
Measuring Granger Causality between Cortical Regions from Voxelwise fMRI BOLD Signals with LASSO pp. 1-14 Downloads
Wei Tang, Steven L Bressler, Chad M Sylvester, Gordon L Shulman and Maurizio Corbetta
Intermittent Motion in Desert Locusts: Behavioural Complexity in Simple Environments pp. 1-10 Downloads
Sepideh Bazazi, Frederic Bartumeus, Joseph J Hale and Iain D Couzin
Resolving the Ortholog Conjecture: Orthologs Tend to Be Weakly, but Significantly, More Similar in Function than Paralogs pp. 1-10 Downloads
Adrian M Altenhoff, Romain A Studer, Marc Robinson-Rechavi and Christophe Dessimoz
Optimal Control of Saccades by Spatial-Temporal Activity Patterns in the Monkey Superior Colliculus pp. 1-18 Downloads
H H L M Goossens and A J van Opstal

Volume 8, issue 4, 2012

Evolutionary Game Theory and Social Learning Can Determine How Vaccine Scares Unfold pp. 1-12 Downloads
Chris T Bauch and Samit Bhattacharyya
Optimizing Provider Recruitment for Influenza Surveillance Networks pp. 1-12 Downloads
Samuel V Scarpino, Nedialko B Dimitrov and Lauren Ancel Meyers
Computational Design of a PDZ Domain Peptide Inhibitor that Rescues CFTR Activity pp. 1-12 Downloads
Kyle E Roberts, Patrick R Cushing, Prisca Boisguerin, Dean R Madden and Bruce R Donald
Tension and Robustness in Multitasking Cellular Networks pp. 1-12 Downloads
Jeffrey V Wong, Bochong Li and Lingchong You
Exploring the Contextual Sensitivity of Factors that Determine Cell-to-Cell Variability in Receptor-Mediated Apoptosis pp. 1-15 Downloads
Suzanne Gaudet, Sabrina L Spencer, William W Chen and Peter K Sorger
Predictive Features of Persistent Activity Emergence in Regular Spiking and Intrinsic Bursting Model Neurons pp. 1-15 Downloads
Kyriaki Sidiropoulou and Panayiota Poirazi
Geometric Theory Predicts Bifurcations in Minimal Wiring Cost Trees in Biology Are Flat pp. 1-7 Downloads
Yihwa Kim, Robert Sinclair, Nol Chindapol, Jaap A Kaandorp and Erik De Schutter
Parameters in Dynamic Models of Complex Traits are Containers of Missing Heritability pp. 1-9 Downloads
Yunpeng Wang, Arne B Gjuvsland, Jon Olav Vik, Nicolas P Smith, Peter J Hunter and Stig W Omholt
Optimization of Muscle Activity for Task-Level Goals Predicts Complex Changes in Limb Forces across Biomechanical Contexts pp. 1-17 Downloads
J Lucas McKay and Lena H Ting
Power-Law Inter-Spike Interval Distributions Infer a Conditional Maximization of Entropy in Cortical Neurons pp. 1-11 Downloads
Yasuhiro Tsubo, Yoshikazu Isomura and Tomoki Fukai
Storage of Correlated Patterns in Standard and Bistable Purkinje Cell Models pp. 1-10 Downloads
Claudia Clopath, Jean-Pierre Nadal and Nicolas Brunel
Theoretical Analysis of Competing Conformational Transitions in Superhelical DNA pp. 1-21 Downloads
Dina Zhabinskaya and Craig J Benham
Are Long-Range Structural Correlations Behind the Aggregration Phenomena of Polyglutamine Diseases? pp. 1-1 Downloads
Mahmoud Moradi, Volodymyr Babin, Christopher Roland and Celeste Sagui

Volume 8, issue 3, 2012

Highly Sensitive and Specific Detection of Rare Variants in Mixed Viral Populations from Massively Parallel Sequence Data pp. 1-10 Downloads
Alexander R Macalalad, Michael C Zody, Patrick Charlebois, Niall J Lennon, Ruchi M Newman, Christine M Malboeuf, Elizabeth M Ryan, Christian L Boutwell, Karen A Power, Doug E Brackney, Kendra N Pesko, Joshua Z Levin, Gregory D Ebel, Todd M Allen, Bruce W Birren and Matthew R Henn
Traffic Instabilities in Self-Organized Pedestrian Crowds pp. 1-10 Downloads
Mehdi Moussaïd, Elsa G Guillot, Mathieu Moreau, Jérôme Fehrenbach, Olivier Chabiron, Samuel Lemercier, Julien Pettré, Cécile Appert-Rolland, Pierre Degond and Guy Theraulaz
A Self-Organizing State-Space-Model Approach for Parameter Estimation in Hodgkin-Huxley-Type Models of Single Neurons pp. 1-1 Downloads
Dimitrios V Vavoulis, Volko A Straub, John A D Aston and Jianfeng Feng
Cortical Surround Interactions and Perceptual Salience via Natural Scene Statistics pp. 1-18 Downloads
Ruben Coen-Cagli, Peter Dayan and Odelia Schwartz
State-Space Analysis of Time-Varying Higher-Order Spike Correlation for Multiple Neural Spike Train Data pp. 1-27 Downloads
Hideaki Shimazaki, Shun-ichi Amari, Emery N Brown and Sonja Grün
Efficient Sparse Coding in Early Sensory Processing: Lessons from Signal Recovery pp. 1-14 Downloads
András Lörincz, Zsolt Palotai and Gábor Szirtes
Uncovering the Dynamics of Cardiac Systems Using Stochastic Pacing and Frequency Domain Analyses pp. 1-14 Downloads
Mathieu Lemay, Enno de Lange and Jan P Kucera
Ten Simple Rules for Starting a Company pp. 1-3 Downloads
Anthony C Fletcher and Philip E Bourne
Impact of Network Structure and Cellular Response on Spike Time Correlations pp. 1-15 Downloads
James Trousdale, Yu Hu, Eric Shea-Brown and Krešimir Josić
Feedforward Inhibition and Synaptic Scaling – Two Sides of the Same Coin? pp. 1-15 Downloads
Christian Keck, Cristina Savin and Jörg Lücke
Ensemble Models of Neutrophil Trafficking in Severe Sepsis pp. 1-16 Downloads
Sang O K Song, Justin Hogg, Zhi-Yong Peng, Robert Parker, John A Kellum and Gilles Clermont

Volume 8, issue 2, 2012

Multi-Scale Modeling of HIV Infection in vitro and APOBEC3G-Based Anti-Retroviral Therapy pp. 1-17 Downloads
Iraj Hosseini and Feilim Mac Gabhann
Human Visual Search Does Not Maximize the Post-Saccadic Probability of Identifying Targets pp. 1-11 Downloads
Camille Morvan and Laurence T Maloney
Joint Analysis of Multiple Metagenomic Samples pp. 1-11 Downloads
Yael Baran and Eran Halperin
Integrating Flux Balance Analysis into Kinetic Models to Decipher the Dynamic Metabolism of Shewanella oneidensis MR-1 pp. 1-11 Downloads
Xueyang Feng, You Xu, Yixin Chen and Yinjie J Tang
Comparison of Insertional RNA Editing in Myxomycetes pp. 1-11 Downloads
Cai Chen, David Frankhouser and Ralf Bundschuh
Paradoxical Evidence Integration in Rapid Decision Processes pp. 1-10 Downloads
Johannes Rüter, Nicolas Marcille, Henning Sprekeler, Wulfram Gerstner and Michael H Herzog
Use It and Improve It or Lose It: Interactions between Arm Function and Use in Humans Post-stroke pp. 1-13 Downloads
Yukikazu Hidaka, Cheol E Han, Steven L Wolf, Carolee J Winstein and Nicolas Schweighofer
Stochastic De-repression of Rhodopsins in Single Photoreceptors of the Fly Retina pp. 1-13 Downloads
Pranidhi Sood, Robert J Johnston and Edo Kussell
Robust Detection of Hierarchical Communities from Escherichia coli Gene Expression Data pp. 1-15 Downloads
Santiago Treviño, Yudong Sun, Tim F Cooper and Kevin E Bassler

Volume 8, issue 1, 2012

Parsimonious Higher-Order Hidden Markov Models for Improved Array-CGH Analysis with Applications to Arabidopsis thaliana pp. 1-15 Downloads
Michael Seifert, André Gohr, Marc Strickert and Ivo Grosse
Protein Design Using Continuous Rotamers pp. 1-15 Downloads
Pablo Gainza, Kyle E Roberts and Bruce R Donald
A Dynamic View of Domain-Motif Interactions pp. 1-13 Downloads
Eyal Akiva, Gilgi Friedlander, Zohar Itzhaki and Hanah Margalit
Kinetic Rate Constant Prediction Supports the Conformational Selection Mechanism of Protein Binding pp. 1-13 Downloads
Iain H Moal and Paul A Bates
Multi-scale Inference of Interaction Rules in Animal Groups Using Bayesian Model Selection pp. 1-12 Downloads
Richard P Mann, Andrea Perna, Daniel Strömbom, Roman Garnett, James E Herbert-Read, David J T Sumpter and Ashley J W Ward
Macro-level Modeling of the Response of C. elegans Reproduction to Chronic Heat Stress pp. 1-12 Downloads
Patrick D McMullen, Erin Z Aprison, Peter B Winter, Luis A N Amaral, Richard I Morimoto and Ilya Ruvinsky
Dynamic Modelling under Uncertainty: The Case of Trypanosoma brucei Energy Metabolism pp. 1-11 Downloads
Fiona Achcar, Eduard J Kerkhoven, The SilicoTryp Consortium, Barbara M Bakker, Michael P Barrett and Rainer Breitling
Joint Modelling of Confounding Factors and Prominent Genetic Regulators Provides Increased Accuracy in Genetical Genomics Studies pp. 1-9 Downloads
Nicoló Fusi, Oliver Stegle and Neil D Lawrence
Failure of Adaptive Self-Organized Criticality during Epileptic Seizure Attacks pp. 1-8 Downloads
Christian Meisel, Alexander Storch, Susanne Hallmeyer-Elgner, Ed Bullmore and Thilo Gross
Adjusting Phenotypes by Noise Control pp. 1-14 Downloads
Kyung H Kim and Herbert M Sauro
Prediction by Promoter Logic in Bacterial Quorum Sensing pp. 1-14 Downloads
Navneet Rai, Rajat Anand, Krishna Ramkumar, Varun Sreenivasan, Sugat Dabholkar, K V Venkatesh and Mukund Thattai
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