PLOS Genetics

2005 - 2022

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Volume 7, issue 12, 2011

Common Variants Show Predicted Polygenic Effects on Height in the Tails of the Distribution, Except in Extremely Short Individuals pp. 1-11

Yingleong Chan, Oddgeir L Holmen, Andrew Dauber, Lars Vatten, Aki S Havulinna, Frank Skorpen, Kirsti Kvaløy, Kaisa Silander, Thutrang T Nguyen, Cristen Willer, Michael Boehnke, Markus Perola, Aarno Palotie, Veikko Salomaa, Kristian Hveem, Timothy M Frayling, Joel N Hirschhorn and Michael N Weedon

Hierarchical Generalized Linear Models for Multiple Groups of Rare and Common Variants: Jointly Estimating Group and Individual-Variant Effects pp. 1-15

Nengjun Yi, Nianjun Liu, Degui Zhi and Jun Li

Ancestral Components of Admixed Genomes in a Mexican Cohort pp. 1-12

Nicholas A Johnson, Marc A Coram, Mark D Shriver, Isabelle Romieu, Gregory S Barsh, Stephanie J London and Hua Tang

Genome-Wide Meta-Analysis of Five Asian Cohorts Identifies PDGFRA as a Susceptibility Locus for Corneal Astigmatism pp. 1-10

Qiao Fan, Xin Zhou, Chiea-Chuen Khor, Ching-Yu Cheng, Liang-Kee Goh, Xueling Sim, Wan-Ting Tay, Yi-Ju Li, Rick Twee-Hee Ong, Chen Suo, Belinda Cornes, Mohammad Kamran Ikram, Kee-Seng Chia, Mark Seielstad, Jianjun Liu, Eranga Vithana, Terri L Young, E-Shyong Tai, Tien-Yin Wong, Tin Aung, Yik-Ying Teo and Seang-Mei Saw

A Comprehensive Analysis of Shared Loci between Systemic Lupus Erythematosus (SLE) and Sixteen Autoimmune Diseases Reveals Limited Genetic Overlap pp. 1-10

Paula S Ramos, Lindsey A Criswell, Kathy L Moser, Mary E Comeau, Adrienne H Williams, Nicholas M Pajewski, Sharon A Chung, Robert R Graham, Raphael Zidovetzki, Jennifer A Kelly, Kenneth M Kaufman, Chaim O Jacob, Timothy J Vyse, Betty P Tsao, Robert P Kimberly, Patrick M Gaffney, Marta E Alarcón-Riquelme, John B Harley, Carl D Langefeld and for The International Consortium on the Genetics of Systemic Erythematosus (slegen)

An Assessment of the Individual and Collective Effects of Variants on Height Using Twins and a Developmentally Informative Study Design pp. 1-10

Scott I Vrieze, Matt McGue, Michael B Miller, Lisa N Legrand, Nicholas J Schork and William G Iacono

Volume 7, issue 10, 2011

A Genome-Wide Screen for Interactions Reveals a New Locus on 4p15 Modifying the Effect of Waist-to-Hip Ratio on Total Cholesterol pp. 1-8

Ida Surakka, Aaron Isaacs, Lennart C Karssen, Pirkka-Pekka P Laurila, Rita P S Middelberg, Emmi Tikkanen, Janina S Ried, Claudia Lamina, Massimo Mangino, Wilmar Igl, Jouke-Jan Hottenga, Vasiliki Lagou, Pim van der Harst, Irene Mateo Leach, Tõnu Esko, Zoltán Kutalik, Nicholas W Wainwright, Maksim V Struchalin, Antti-Pekka Sarin, Antti J Kangas, Jorma S Viikari, Markus Perola, Taina Rantanen, Ann-Kristin Petersen, Pasi Soininen, Åsa Johansson, Nicole Soranzo, Andrew C Heath, Theodore Papamarkou, Inga Prokopenko, Anke Tönjes, Florian Kronenberg, Angela Döring, Fernando Rivadeneira, Grant W Montgomery, John B Whitfield, Mika Kähönen, Terho Lehtimäki, Nelson B Freimer, Gonneke Willemsen, Eco J C de Geus, Aarno Palotie, Manj S Sandhu, Dawn M Waterworth, Andres Metspalu, Michael Stumvoll, André G Uitterlinden, Antti Jula, Gerjan Navis, Cisca Wijmenga, Bruce H R Wolffenbuttel, Marja-Riitta Taskinen, Mika Ala-Korpela, Jaakko Kaprio, Kirsten O Kyvik, Dorret I Boomsma, Nancy L Pedersen, Ulf Gyllensten, James F Wilson, Igor Rudan, Harry Campbell, Peter P Pramstaller, Tim D Spector, Jacqueline C M Witteman, Johan G Eriksson, Veikko Salomaa, Ben A Oostra, Olli T Raitakari, H-Erich Wichmann, Christian Gieger, Marjo-Riitta Järvelin, Nicholas G Martin, Albert Hofman, Mark I McCarthy, Leena Peltonen, Cornelia M van Duijn, Yurii S Aulchenko, Samuli Ripatti and for the ENGAGE Consortium

Natural Selection Affects Multiple Aspects of Genetic Variation at Putatively Neutral Sites across the Human Genome pp. 1-15

Kirk E Lohmueller, Anders Albrechtsen, Yingrui Li, Su Yeon Kim, Thorfinn Korneliussen, Nicolas Vinckenbosch, Geng Tian, Emilia Huerta-Sanchez, Alison F Feder, Niels Grarup, Torben Jørgensen, Tao Jiang, Daniel R Witte, Annelli Sandbæk, Ines Hellmann, Torsten Lauritzen, Torben Hansen, Oluf Pedersen, Jun Wang and Rasmus Nielsen

Identification, Replication, and Fine-Mapping of Loci Associated with Adult Height in Individuals of African Ancestry pp. 1-11

Amidou N'Diaye, Gary K Chen, Cameron D Palmer, Bing Ge, Bamidele Tayo, Rasika A Mathias, Jingzhong Ding, Michael A Nalls, Adebowale Adeyemo, Véronique Adoue, Christine B Ambrosone, Larry Atwood, Elisa V Bandera, Lewis C Becker, Sonja I Berndt, Leslie Bernstein, William J Blot, Eric Boerwinkle, Angela Britton, Graham Casey, Stephen J Chanock, Ellen Demerath, Sandra L Deming, W Ryan Diver, Caroline Fox, Tamara B Harris, Dena G Hernandez, Jennifer J Hu, Sue A Ingles, Esther M John, Craig Johnson, Brendan Keating, Rick A Kittles, Laurence N Kolonel, Stephen B Kritchevsky, Loic Le Marchand, Kurt Lohman, Jiankang Liu, Robert C Millikan, Adam Murphy, Solomon Musani, Christine Neslund-Dudas, Kari E North, Sarah Nyante, Adesola Ogunniyi, Elaine A Ostrander, George Papanicolaou, Sanjay Patel, Curtis A Pettaway, Michael F Press, Susan Redline, Jorge L Rodriguez-Gil, Charles Rotimi, Benjamin A Rybicki, Babatunde Salako, Pamela J Schreiner, Lisa B Signorello, Andrew B Singleton, Janet L Stanford, Alex H Stram, Daniel O Stram, Sara S Strom, Bhoom Suktitipat, Michael J Thun, John S Witte, Lisa R Yanek, Regina G Ziegler, Wei Zheng, Xiaofeng Zhu, Joseph M Zmuda, Alan B Zonderman, Michele K Evans, Yongmei Liu, Diane M Becker, Richard S Cooper, Tomi Pastinen, Brian E Henderson, Joel N Hirschhorn, Guillaume Lettre and Christopher A Haiman

Genetic Determinants of Serum Testosterone Concentrations in Men pp. 1-11

Claes Ohlsson, Henri Wallaschofski, Kathryn L Lunetta, Lisette Stolk, John R B Perry, Annemarie Koster, Ann-Kristin Petersen, Joel Eriksson, Terho Lehtimäki, Ilpo T Huhtaniemi, Geoffrey L Hammond, Marcello Maggio, Andrea D Coviello, Study Group Emas, Luigi Ferrucci, Margit Heier, Albert Hofman, Kate L Holliday, John-Olov Jansson, Mika Kähönen, David Karasik, Magnus K Karlsson, Douglas P Kiel, Yongmei Liu, Östen Ljunggren, Mattias Lorentzon, Leo-Pekka Lyytikäinen, Thomas Meitinger, Dan Mellström, David Melzer, Iva Miljkovic, Matthias Nauck, Maria Nilsson, Brenda Penninx, Stephen R Pye, Ramachandran S Vasan, Martin Reincke, Fernando Rivadeneira, Abdelouahid Tajar, Alexander Teumer, André G Uitterlinden, Jagadish Ulloor, Jorma Viikari, Uwe Völker, Henry Völzke, H Erich Wichmann, Tsung-Sheng Wu, Wei Vivian Zhuang, Elad Ziv, Frederick C W Wu, Olli Raitakari, Anna Eriksson, Martin Bidlingmaier, Tamara B Harris, Anna Murray, Frank H de Jong, Joanne M Murabito, Shalender Bhasin, Liesbeth Vandenput and Robin Haring

Association of NCF2, IKZF1, IRF8, IFIH1, and TYK2 with Systemic Lupus Erythematosus pp. 1-9

Deborah S Cunninghame Graham, David L Morris, Tushar R Bhangale, Lindsey A Criswell, Ann-Christine Syvänen, Lars Rönnblom, Timothy W Behrens, Robert R Graham and Timothy J Vyse

Volume 7, issue 9, 2011

Association of eGFR-Related Loci Identified by GWAS with Incident CKD and ESRD pp. 1-8

Carsten A Böger, Mathias Gorski, Man Li, Michael M Hoffmann, Chunmei Huang, Qiong Yang, Alexander Teumer, Vera Krane, Conall M O'Seaghdha, Zoltán Kutalik, H-Erich Wichmann, Thomas Haak, Eva Boes, Stefan Coassin, Josef Coresh, Barbara Kollerits, Margot Haun, Bernhard Paulweber, Anna Köttgen, Guo Li, Michael G Shlipak, Neil Powe, Shih-Jen Hwang, Abbas Dehghan, Fernando Rivadeneira, André Uitterlinden, Albert Hofman, Jacques S Beckmann, Bernhard K Krämer, Jacqueline Witteman, Murielle Bochud, David Siscovick, Rainer Rettig, Florian Kronenberg, Christoph Wanner, Ravi I Thadhani, Iris M Heid, Caroline S Fox, W H Kao and The CKDGen Consortium

A Genome-Wide Meta-Analysis of Six Type 1 Diabetes Cohorts Identifies Multiple Associated Loci pp. 1-8

Jonathan P Bradfield, Hui-Qi Qu, Kai Wang, Haitao Zhang, Patrick M Sleiman, Cecilia E Kim, Frank D Mentch, Haijun Qiu, Joseph T Glessner, Kelly A Thomas, Edward C Frackelton, Rosetta M Chiavacci, Marcin Imielinski, Dimitri S Monos, Rahul Pandey, Marina Bakay, Struan F A Grant, Constantin Polychronakos and Hakon Hakonarson

Inference of Relationships in Population Data Using Identity-by-Descent and Identity-by-State pp. 1-15

Eric L Stevens, Greg Heckenberg, Elisha D O Roberson, Joseph D Baugher, Thomas J Downey and Jonathan Pevsner

An Iterative Genetic and Dynamical Modelling Approach Identifies Novel Features of the Gene Regulatory Network Underlying Melanocyte Development pp. 1-18

Emma R Greenhill, Andrea Rocco, Laura Vibert, Masataka Nikaido and Robert N Kelsh

Temporal Trends in Results Availability from Genome-Wide Association Studies pp. 1-3

Andrew D Johnson, Richard Leslie and Christopher J O'Donnell

Large-Scale Gene-Centric Analysis Identifies Novel Variants for Coronary Artery Disease pp. 1-14

The IBC 50K CAD Consortium

Volume 7, issue 8, 2011

Discovery of Sexual Dimorphisms in Metabolic and Genetic Biomarkers pp. 1-12

Kirstin Mittelstrass, Janina S Ried, Zhonghao Yu, Jan Krumsiek, Christian Gieger, Cornelia Prehn, Werner Roemisch-Margl, Alexey Polonikov, Annette Peters, Fabian J Theis, Thomas Meitinger, Florian Kronenberg, Stephan Weidinger, Heinz Erich Wichmann, Karsten Suhre, Rui Wang-Sattler, Jerzy Adamski and Thomas Illig

Genome-Wide Association Analysis of Autoantibody Positivity in Type 1 Diabetes Cases pp. 1-9

Vincent Plagnol, Joanna M M Howson, Deborah J Smyth, Neil Walker, Jason P Hafler, Chris Wallace, Helen Stevens, Laura Jackson, Matthew J Simmonds, Type 1 Diabetes Genetics Consortium, Polly J Bingley, Stephen C Gough and John A Todd

Volume 7, issue 7, 2011

Identification of Novel Genetic Markers Associated with Clinical Phenotypes of Systemic Sclerosis through a Genome-Wide Association Strategy pp. 1-11

Olga Gorlova, Jose-Ezequiel Martin, Blanca Rueda, Bobby P C Koeleman, Jun Ying, Maria Teruel, Lina-Marcela Diaz-Gallo, Jasper C Broen, Madelon C Vonk, Carmen P Simeon, Behrooz Z Alizadeh, Marieke J H Coenen, Alexandre E Voskuyl, Annemie J Schuerwegh, Piet L C M van Riel, Marie Vanthuyne, Ruben van 't Slot, Annet Italiaander, Roel A Ophoff, Nicolas Hunzelmann, Vicente Fonollosa, Norberto Ortego-Centeno, Miguel A González-Gay, Francisco J García-Hernández, María F González-Escribano, Paolo Airo, Jacob van Laar, Jane Worthington, Roger Hesselstrand, Vanessa Smith, Filip de Keyser, Fredric Houssiau, Meng May Chee, Rajan Madhok, Paul G Shiels, Rene Westhovens, Alexander Kreuter, Elfride de Baere, Torsten Witte, Leonid Padyukov, Annika Nordin, Raffaella Scorza, Claudio Lunardi, Benedicte A Lie, Anna-Maria Hoffmann-Vold, Øyvind Palm, Paloma García de la Peña, Patricia Carreira, Spanish Scleroderma Group, John Varga, Monique Hinchcliff, Annette T Lee, Pravitt Gourh, Christopher I Amos, Frederick M Wigley, Laura K Hummers, J Hummers, J Lee Nelson, Gabriella Riemekasten, Ariane Herrick, Lorenzo Beretta, Carmen Fonseca, Christopher P Denton, Peter K Gregersen, Sandeep Agarwal, Shervin Assassi, Filemon K Tan, Frank C Arnett, Timothy R D J Radstake, Maureen D Mayes and Javier Martin

Gene-Based Tests of Association pp. 1-15

Hailiang Huang, Pritam Chanda, Alvaro Alonso, Joel S Bader and Dan E Arking

Genome-Wide Association Study Identifies Novel Restless Legs Syndrome Susceptibility Loci on 2p14 and 16q12.1 pp. 1-10

Juliane Winkelmann, Darina Czamara, Barbara Schormair, Franziska Knauf, Eva C Schulte, Claudia Trenkwalder, Yves Dauvilliers, Olli Polo, Birgit Högl, Klaus Berger, Andrea Fuhs, Nadine Gross, Karin Stiasny-Kolster, Wolfgang Oertel, Cornelius G Bachmann, Walter Paulus, Lan Xiong, Jacques Montplaisir, Guy A Rouleau, Ingo Fietze, Jana Vávrová, David Kemlink, Karel Sonka, Sona Nevsimalova, Siong-Chi Lin, Zbigniew Wszolek, Carles Vilariño-Güell, Matthew J Farrer, Viola Gschliesser, Birgit Frauscher, Tina Falkenstetter, Werner Poewe, Richard P Allen, Christopher J Earley, William G Ondo, Wei-Dong Le, Derek Spieler, Maria Kaffe, Alexander Zimprich, Johannes Kettunen, Markus Perola, Kaisa Silander, Isabelle Cournu-Rebeix, Marcella Francavilla, Claire Fontenille, Bertrand Fontaine, Pavel Vodicka, Holger Prokisch, Peter Lichtner, Paul Peppard, Juliette Faraco, Emmanuel Mignot, Christian Gieger, Thomas Illig, H-Erich Wichmann, Bertram Müller-Myhsok and Thomas Meitinger

Genetic Loci Associated with Plasma Phospholipid n-3 Fatty Acids: A Meta-Analysis of Genome-Wide Association Studies from the CHARGE Consortium pp. 1-12

Rozenn N Lemaitre, Toshiko Tanaka, Weihong Tang, Ani Manichaikul, Millennia Foy, Edmond K Kabagambe, Jennifer A Nettleton, Irena B King, Lu-Chen Weng, Sayanti Bhattacharya, Stefania Bandinelli, Joshua C Bis, Stephen S Rich, David R Jacobs, Antonio Cherubini, Barbara McKnight, Shuang Liang, Xiangjun Gu, Kenneth Rice, Cathy C Laurie, Thomas Lumley, Brian L Browning, Bruce M Psaty, Yii- Der I Chen, Yechiel Friedlander, Luc Djousse, Jason H Y Wu, David S Siscovick, André G Uitterlinden, Donna K Arnett, Luigi Ferrucci, Myriam Fornage, Michael Y Tsai, Dariush Mozaffarian and Lyn M Steffen

Volume 7, issue 6, 2011

Genetic Determinants of Lipid Traits in Diverse Populations from the Population Architecture using Genomics and Epidemiology (PAGE) Study pp. 1-15

Logan Dumitrescu, Cara L Carty, Kira Taylor, Fredrick R Schumacher, Lucia A Hindorff, José L Ambite, Garnet Anderson, Lyle G Best, Kristin Brown-Gentry, Petra Bůžková, Christopher S Carlson, Barbara Cochran, Shelley A Cole, Richard B Devereux, Dave Duggan, Charles B Eaton, Myriam Fornage, Nora Franceschini, Jeff Haessler, Barbara V Howard, Karen C Johnson, Sandra Laston, Laurence N Kolonel, Elisa T Lee, Jean W MacCluer, Teri A Manolio, Sarah A Pendergrass, Miguel Quibrera, Ralph V Shohet, Lynne R Wilkens, Christopher A Haiman, Loïc Le Marchand, Steven Buyske, Charles Kooperberg, Kari E North and Dana C Crawford

Genomic Prevalence of Heterochromatic H3K9me2 and Transcription Do Not Discriminate Pluripotent from Terminally Differentiated Cells pp. 1-9

Florian Lienert, Fabio Mohn, Vijay K Tiwari, Tuncay Baubec, Tim C Roloff, Dimos Gaidatzis, Michael B Stadler and Dirk Schübeler

A Two-Stage Meta-Analysis Identifies Several New Loci for Parkinson's Disease pp. 1-9

International Parkinson's Disease Genomics Consortium (ipdgc) and Wellcome Trust Case Control Consortium 2 (wtccc2)

Identification of a Sudden Cardiac Death Susceptibility Locus at 2q24.2 through Genome-Wide Association in European Ancestry Individuals pp. 1-9

Dan E Arking, M Juhani Junttila, Philippe Goyette, Adriana Huertas-Vazquez, Mark Eijgelsheim, Marieke T Blom, Christopher Newton-Cheh, Kyndaron Reinier, Carmen Teodorescu, Audrey Uy-Evanado, Naima Carter-Monroe, Kari S Kaikkonen, Marja-Leena Kortelainen, Gabrielle Boucher, Caroline Lagacé, Anna Moes, XiaoQing Zhao, Frank Kolodgie, Fernando Rivadeneira, Albert Hofman, Jacqueline C M Witteman, André G Uitterlinden, Roos F Marsman, Raha Pazoki, Abdennasser Bardai, Rudolph W Koster, Abbas Dehghan, Shih-Jen Hwang, Pallav Bhatnagar, Wendy Post, Gina Hilton, Ronald J Prineas, Man Li, Anna Köttgen, Georg Ehret, Eric Boerwinkle, Josef Coresh, W H Linda Kao, Bruce M Psaty, Gordon F Tomaselli, Nona Sotoodehnia, David S Siscovick, Greg L Burke, Eduardo Marbán, Peter M Spooner, L Adrienne Cupples, Jonathan Jui, Karen Gunson, Y Antero Kesäniemi, Arthur A M Wilde, Jean-Claude Tardif, Christopher J O'Donnell, Connie R Bezzina, Renu Virmani, Bruno H C h Stricker, Hanno L Tan, Christine M Albert, Aravinda Chakravarti, John D Rioux, Heikki V Huikuri and Sumeet S Chugh

Genome-Wide Association of Bipolar Disorder Suggests an Enrichment of Replicable Associations in Regions near Genes pp. 1-10

Erin N Smith, Daniel L Koller, Corrie Panganiban, Szabolcs Szelinger, Peng Zhang, Judith A Badner, Thomas B Barrett, Wade H Berrettini, Cinnamon S Bloss, William Byerley, William Coryell, Howard J Edenberg, Tatiana Foroud, Elliot S Gershon, Tiffany A Greenwood, Yiran Guo, Maria Hipolito, Brendan J Keating, William B Lawson, Chunyu Liu, Pamela B Mahon, Melvin G McInnis, Francis J McMahon, Rebecca McKinney, Sarah S Murray, Caroline M Nievergelt, John I Nurnberger, Evaristus A Nwulia, James B Potash, John Rice, Thomas G Schulze, William A Scheftner, Paul D Shilling, Peter P Zandi, Sebastian Zöllner, David W Craig, Nicholas J Schork and John R Kelsoe

Multiple Loci Are Associated with White Blood Cell Phenotypes pp. 1-16

Michael A Nalls, David J Couper, Toshiko Tanaka, Frank J A van Rooij, Ming-Huei Chen, Albert V Smith, Daniela Toniolo, Neil A Zakai, Qiong Yang, Andreas Greinacher, Andrew R Wood, Melissa Garcia, Paolo Gasparini, Yongmei Liu, Thomas Lumley, Aaron R Folsom, Alex P Reiner, Christian Gieger, Vasiliki Lagou, Janine F Felix, Henry Völzke, Natalia A Gouskova, Alessandro Biffi, Angela Döring, Uwe Völker, Sean Chong, Kerri L Wiggins, Augusto Rendon, Abbas Dehghan, Matt Moore, Kent Taylor, James G Wilson, Guillaume Lettre, Albert Hofman, Joshua C Bis, Nicola Pirastu, Caroline S Fox, Christa Meisinger, Jennifer Sambrook, Sampath Arepalli, Matthias Nauck, Holger Prokisch, Jonathan Stephens, Nicole L Glazer, L Adrienne Cupples, Yukinori Okada, Atsushi Takahashi, Yoichiro Kamatani, Koichi Matsuda, Tatsuhiko Tsunoda, Toshihiro Tanaka, Michiaki Kubo, Yusuke Nakamura, Kazuhiko Yamamoto, Naoyuki Kamatani, Michael Stumvoll, Anke Tönjes, Inga Prokopenko, Thomas Illig, Kushang V Patel, Stephen F Garner, Brigitte Kuhnel, Massimo Mangino, Ben A Oostra, Swee Lay Thein, Josef Coresh, H-Erich Wichmann, Stephan Menzel, JingPing Lin, Giorgio Pistis, André G Uitterlinden, Tim D Spector, Alexander Teumer, Gudny Eiriksdottir, Vilmundur Gudnason, Stefania Bandinelli, Timothy M Frayling, Aravinda Chakravarti, Cornelia M van Duijn, David Melzer, Willem H Ouwehand, Daniel Levy, Eric Boerwinkle, Andrew B Singleton, Dena G Hernandez, Dan L Longo, Nicole Soranzo, Jacqueline C M Witteman, Bruce M Psaty, Luigi Ferrucci, Tamara B Harris, Christopher J O'Donnell and Santhi K Ganesh

Genome-Wide Association Study of White Blood Cell Count in 16,388 African Americans: the Continental Origins and Genetic Epidemiology Network (COGENT) pp. 1-14

Alexander P Reiner, Guillaume Lettre, Michael A Nalls, Santhi K Ganesh, Rasika Mathias, Melissa A Austin, Eric Dean, Sampath Arepalli, Angela Britton, Zhao Chen, David Couper, J David Curb, Charles B Eaton, Myriam Fornage, Struan F A Grant, Tamara B Harris, Dena Hernandez, Naoyuki Kamatini, Brendan J Keating, Michiaki Kubo, Andrea LaCroix, Leslie A Lange, Simin Liu, Kurt Lohman, Yan Meng, Emile R Mohler, Solomon Musani, Yusuke Nakamura, Christopher J O'Donnell, Yukinori Okada, Cameron D Palmer, George J Papanicolaou, Kushang V Patel, Andrew B Singleton, Atsushi Takahashi, Hua Tang, Herman A Taylor, Kent Taylor, Cynthia Thomson, Lisa R Yanek, Lingyao Yang, Elad Ziv, Alan B Zonderman, Aaron R Folsom, Michele K Evans, Yongmei Liu, Diane M Becker, Beverly M Snively and James G Wilson

Web-Based Genome-Wide Association Study Identifies Two Novel Loci and a Substantial Genetic Component for Parkinson's Disease pp. 1-14

Chuong B Do, Joyce Y Tung, Elizabeth Dorfman, Amy K Kiefer, Emily M Drabant, Uta Francke, Joanna L Mountain, Samuel M Goldman, Caroline M Tanner, J William Langston, Anne Wojcicki and Nicholas Eriksson

Volume 7, issue 5, 2011

Identification, Replication, and Functional Fine-Mapping of Expression Quantitative Trait Loci in Primary Human Liver Tissue pp. 1-16

Federico Innocenti, Gregory M Cooper, Ian B Stanaway, Eric R Gamazon, Joshua D Smith, Snezana Mirkov, Jacqueline Ramirez, Wanqing Liu, Yvonne S Lin, Cliona Moloney, Shelly Force Aldred, Nathan D Trinklein, Erin Schuetz, Deborah A Nickerson, Ken E Thummel, Mark J Rieder, Allan E Rettie, Mark J Ratain, Nancy J Cox and Christopher D Brown

Volume 7, issue 4, 2011

Transferability of Type 2 Diabetes Implicated Loci in Multi-Ethnic Cohorts from Southeast Asia pp. 1-12

Xueling Sim, Rick Twee-Hee Ong, Chen Suo, Wan-Ting Tay, Jianjun Liu, Daniel Peng-Keat Ng, Michael Boehnke, Kee-Seng Chia, Tien-Yin Wong, Mark Seielstad, Yik-Ying Teo and E-Shyong Tai

Eight Common Genetic Variants Associated with Serum DHEAS Levels Suggest a Key Role in Ageing Mechanisms pp. 1-10

Guangju Zhai, Alexander Teumer, Lisette Stolk, John R B Perry, Liesbeth Vandenput, Andrea D Coviello, Annemarie Koster, Jordana T Bell, Shalender Bhasin, Joel Eriksson, Anna Eriksson, Florian Ernst, Luigi Ferrucci, Timothy M Frayling, Daniel Glass, Elin Grundberg, Robin Haring, Åsa K Hedman, Albert Hofman, Douglas P Kiel, Heyo K Kroemer, Yongmei Liu, Kathryn L Lunetta, Marcello Maggio, Mattias Lorentzon, Massimo Mangino, David Melzer, Iva Miljkovic, MuTHER Consortium, Alexandra Nica, Brenda W J H Penninx, Ramachandran S Vasan, Fernando Rivadeneira, Kerrin S Small, Nicole Soranzo, André G Uitterlinden, Henry Völzke, Scott G Wilson, Li Xi, Wei Vivian Zhuang, Tamara B Harris, Joanne M Murabito, Claes Ohlsson, Anna Murray, Frank H de Jong, Tim D Spector and Henri Wallaschofski

Genome-Wide Meta-Analysis Identifies Regions on 7p21 (AHR) and 15q24 (CYP1A2) As Determinants of Habitual Caffeine Consumption pp. 1-9

Marilyn C Cornelis, Keri L Monda, Kai Yu, Nina Paynter, Elizabeth M Azzato, Siiri N Bennett, Sonja I Berndt, Eric Boerwinkle, Stephen Chanock, Nilanjan Chatterjee, David Couper, Gary Curhan, Gerardo Heiss, Frank B Hu, David J Hunter, Kevin Jacobs, Majken K Jensen, Peter Kraft, Maria Teresa Landi, Jennifer A Nettleton, Mark P Purdue, Preetha Rajaraman, Eric B Rimm, Lynda M Rose, Nathaniel Rothman, Debra Silverman, Rachael Stolzenberg-Solomon, Amy Subar, Meredith Yeager, Daniel I Chasman, Rob M van Dam and Neil E Caporaso

Beyond Missing Heritability: Prediction of Complex Traits pp. 1-9

Robert Makowsky, Nicholas M Pajewski, Yann C Klimentidis, Ana I Vazquez, Christine W Duarte, David B Allison and Gustavo de los Campos

Incorporating Biological Pathways via a Markov Random Field Model in Genome-Wide Association Studies pp. 1-13

Min Chen, Judy Cho and Hongyu Zhao

The History of African Gene Flow into Southern Europeans, Levantines, and Jews pp. 1-13

Priya Moorjani, Nick Patterson, Joel N Hirschhorn, Alon Keinan, Li Hao, Gil Atzmon, Edward Burns, Harry Ostrer, Alkes L Price and David Reich

Volume 7, issue 3, 2011

Phenotype Restricted Genome-Wide Association Study Using a Gene-Centric Approach Identifies Three Low-Risk Neuroblastoma Susceptibility Loci pp. 1-9

Lễ B Nguyễn, Sharon J Diskin, Mario Capasso, Kai Wang, Maura A Diamond, Joseph Glessner, Cecilia Kim, Edward F Attiyeh, Yael P Mosse, Kristina Cole, Achille Iolascon, Marcella Devoto, Hakon Hakonarson, Hongzhe K Li and John M Maris

Genome-Wide Interaction-Based Association Analysis Identified Multiple New Susceptibility Loci for Common Diseases pp. 1-16

Yang Liu, Haiming Xu, Suchao Chen, Xianfeng Chen, Zhenguo Zhang, Zhihong Zhu, Xueying Qin, Landian Hu, Jun Zhu, Guo-Ping Zhao and Xiangyin Kong

Estimating Divergence Time and Ancestral Effective Population Size of Bornean and Sumatran Orangutan Subspecies Using a Coalescent Hidden Markov Model pp. 1-15

Thomas Mailund, Julien Y Dutheil, Asger Hobolth, Gerton Lunter and Mikkel H Schierup

Testing for an Unusual Distribution of Rare Variants pp. 1-8

Benjamin M Neale, Manuel A Rivas, Benjamin F Voight, David Altshuler, Bernie Devlin, Marju Orho-Melander, Sekar Kathiresan, Shaun M Purcell, Kathryn Roeder and Mark J Daly

Volume 7, issue 2, 2011

Genome-Wide Association Study of Coronary Heart Disease and Its Risk Factors in 8,090 African Americans: The NHLBI CARe Project pp. 1-11

Guillaume Lettre, Cameron D Palmer, Taylor Young, Kenechi G Ejebe, Hooman Allayee, Emelia J Benjamin, Franklyn Bennett, Donald W Bowden, Aravinda Chakravarti, Al Dreisbach, Deborah N Farlow, Aaron R Folsom, Myriam Fornage, Terrence Forrester, Ervin Fox, Christopher A Haiman, Jaana Hartiala, Tamara B Harris, Stanley L Hazen, Susan R Heckbert, Brian E Henderson, Joel N Hirschhorn, Brendan J Keating, Stephen B Kritchevsky, Emma Larkin, Mingyao Li, Megan E Rudock, Colin A McKenzie, James B Meigs, Yang A Meng, Tom H Mosley, Anne B Newman, Christopher H Newton-Cheh, Dina N Paltoo, George J Papanicolaou, Nick Patterson, Wendy S Post, Bruce M Psaty, Atif N Qasim, Liming Qu, Daniel J Rader, Susan Redline, Muredach P Reilly, Alexander P Reiner, Stephen S Rich, Jerome I Rotter, Yongmei Liu, Peter Shrader, David S Siscovick, W H Wilson Tang, Herman A Taylor, Russell P Tracy, Ramachandran S Vasan, Kevin M Waters, Rainford Wilks, James G Wilson, Richard R Fabsitz, Stacey B Gabriel, Sekar Kathiresan and Eric Boerwinkle

A New Testing Strategy to Identify Rare Variants with Either Risk or Protective Effect on Disease pp. 1-6

Iuliana Ionita-Laza, Joseph D Buxbaum, Nan M Laird and Christoph Lange

Association between Common Variation at the FTO Locus and Changes in Body Mass Index from Infancy to Late Childhood: The Complex Nature of Genetic Association through Growth and Development pp. 1-13

Ulla Sovio, Dennis O Mook-Kanamori, Nicole M Warrington, Robert Lawrence, Laurent Briollais, Colin N A Palmer, Joanne Cecil, Johanna K Sandling, Ann-Christine Syvänen, Marika Kaakinen, Lawrie J Beilin, Iona Y Millwood, Amanda J Bennett, Jaana Laitinen, Anneli Pouta, John Molitor, George Davey Smith, Yoav Ben-Shlomo, Vincent W V Jaddoe, Lyle J Palmer, Craig E Pennell, Tim J Cole, Mark I McCarthy, Marjo-Riitta Järvelin, Nicholas J Timpson and Early Growth Genetics Consortium

Meta-Analysis of Genome-Wide Association Studies in Celiac Disease and Rheumatoid Arthritis Identifies Fourteen Non-HLA Shared Loci pp. 1-13

Alexandra Zhernakova, Eli A Stahl, Gosia Trynka, Soumya Raychaudhuri, Eleanora A Festen, Lude Franke, Harm-Jan Westra, Rudolf S N Fehrmann, Fina A S Kurreeman, Brian Thomson, Namrata Gupta, Jihane Romanos, Ross McManus, Anthony W Ryan, Graham Turner, Elisabeth Brouwer, Marcel D Posthumus, Elaine F Remmers, Francesca Tucci, Rene Toes, Elvira Grandone, Maria Cristina Mazzilli, Anna Rybak, Bozena Cukrowska, Marieke J H Coenen, Timothy R D J Radstake, Piet L C M van Riel, Yonghong Li, Paul I W de Bakker, Peter K Gregersen, Jane Worthington, Katherine A Siminovitch, Lars Klareskog, Tom W J Huizinga, Cisca Wijmenga and Robert M Plenge

A Population Genetic Approach to Mapping Neurological Disorder Genes Using Deep Resequencing pp. 1-10

Rachel A Myers, Ferran Casals, Julie Gauthier, Fadi F Hamdan, Jon Keebler, Adam R Boyko, Carlos D Bustamante, Amelie M Piton, Dan Spiegelman, Edouard Henrion, Martine Zilversmit, Julie Hussin, Jacklyn Quinlan, Yan Yang, Ronald G Lafrenière, Alexander R Griffing, Eric A Stone, Guy A Rouleau and Philip Awadalla

Genome-Wide Association Studies of the PR Interval in African Americans pp. 1-9

J Gustav Smith, Jared W Magnani, Cameron Palmer, Yan A Meng, Elsayed Z Soliman, Solomon K Musani, Kathleen F Kerr, Renate B Schnabel, Steven A Lubitz, Nona Sotoodehnia, Susan Redline, Arne Pfeufer, Martina Müller, Daniel S Evans, Michael A Nalls, Yongmei Liu, Anne B Newman, Alan B Zonderman, Michele K Evans, Rajat Deo, Patrick T Ellinor, Dina N Paltoo, Christopher Newton-Cheh, Emelia J Benjamin, Reena Mehra, Alvaro Alonso, Susan R Heckbert, Ervin R Fox and Candidate-gene Association Resource (CARe) Consortium

Single-Tissue and Cross-Tissue Heritability of Gene Expression Via Identity-by-Descent in Related or Unrelated Individuals pp. 1-9

Alkes L Price, Agnar Helgason, Gudmar Thorleifsson, Steven A McCarroll, Augustine Kong and Kari Stefansson

The Architecture of Gene Regulatory Variation across Multiple Human Tissues: The MuTHER Study pp. 1-9

Alexandra C Nica, Leopold Parts, Daniel Glass, James Nisbet, Amy Barrett, Magdalena Sekowska, Mary Travers, Simon Potter, Elin Grundberg, Kerrin Small, Åsa K Hedman, Veronique Bataille, Jordana Tzenova Bell, Gabriela Surdulescu, Antigone S Dimas, Catherine Ingle, Frank O Nestle, Paola di Meglio, Josine L Min, Alicja Wilk, Christopher J Hammond, Neelam Hassanali, Tsun-Po Yang, Stephen B Montgomery, Steve O'Rahilly, Cecilia M Lindgren, Krina T Zondervan, Nicole Soranzo, Inês Barroso, Richard Durbin, Kourosh Ahmadi, Panos Deloukas, Mark I McCarthy, Emmanouil T Dermitzakis, Timothy D Spector and The MuTHER Consortium

Volume 7, issue 1, 2011

Application of a New Method for GWAS in a Related Case/Control Sample with Known Pedigree Structure: Identification of New Loci for Nephrolithiasis pp. 1-15

Silvia Tore, Stefania Casula, Giuseppina Casu, Maria Pina Concas, Paola Pistidda, Ivana Persico, Alessandro Sassu, Giovanni Battista Maestrale, Caterina Mele, Maria Rosa Caruso, Bibiana Bonerba, Paolo Usai, Ivo Deiana, Timothy Thornton, Mario Pirastu and Paola Forabosco

A Meta-Analysis of Genome-Wide Association Scans Identifies IL18RAP, PTPN2, TAGAP, and PUS10 As Shared Risk Loci for Crohn's Disease and Celiac Disease pp. 1-6

Eleonora A M Festen, Philippe Goyette, Todd Green, Gabrielle Boucher, Claudine Beauchamp, Gosia Trynka, Patrick C Dubois, Caroline Lagacé, Pieter C F Stokkers, Daan W Hommes, Donatella Barisani, Orazio Palmieri, Vito Annese, David A van Heel, Rinse K Weersma, Mark J Daly, Cisca Wijmenga and John D Rioux

Joint Genetic Analysis of Gene Expression Data with Inferred Cellular Phenotypes pp. 1-10

Leopold Parts, Oliver Stegle, John Winn and Richard Durbin

Global Analysis of the Impact of Environmental Perturbation on cis-Regulation of Gene Expression pp. 1-17

Elin Grundberg, Veronique Adoue, Tony Kwan, Bing Ge, Qing Ling Duan, Kevin C L Lam, Vonda Koka, Andreas Kindmark, Scott T Weiss, Kelan Tantisira, Hans Mallmin, Benjamin A Raby, Olle Nilsson and Tomi Pastinen