PLOS Genetics

2005 - 2025

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Volume 4, issue 12, 2008

Practical Issues in Imputation-Based Association Mapping pp. 1-11

Yongtao Guan and Matthew Stephens

The Population Genetics of dN/dS pp. 1-10

Sergey Kryazhimskiy and Joshua B Plotkin

Volume 4, issue 11, 2008

Genetic Analysis of Human Traits In Vitro: Drug Response and Gene Expression in Lymphoblastoid Cell Lines pp. 1-16

Edwin Choy, Roman Yelensky, Sasha Bonakdar, Robert M Plenge, Richa Saxena, Philip L De Jager, Stanley Y Shaw, Cara S Wolfish, Jacqueline M Slavik, Chris Cotsapas, Manuel Rivas, Emmanouil T Dermitzakis, Ellen Cahir-McFarland, Elliott Kieff, David Hafler, Mark J Daly and David Altshuler

Volume 4, issue 10, 2008

Efficient and Accurate Construction of Genetic Linkage Maps from the Minimum Spanning Tree of a Graph pp. 1-11

Yonghui Wu, Prasanna R Bhat, Timothy J Close and Stefano Lonardi

Volume 4, issue 9, 2008

A Review of Family-Based Tests for Linkage Disequilibrium between a Quantitative Trait and a Genetic Marker pp. 1-6

Warren J Ewens, Mingyao Li and Richard S Spielman

Screening and Replication using the Same Data Set: Testing Strategies for Family-Based Studies in which All Probands Are Affected pp. 1-10

Amy Murphy, Scott T Weiss and Christoph Lange

Volume 4, issue 8, 2008

A Tribute to Evgenii V. Ananiev, 1947–2008 pp. 1-3

Sergei M Mirkin

Identification and Functional Analysis of Light-Responsive Unique Genes and Gene Family Members in Rice pp. 1-19

Ki-Hong Jung, Jinwon Lee, Chris Dardick, Young-Su Seo, Peijian Cao, Patrick Canlas, Jirapa Phetsom, Xia Xu, Shu Ouyang, Kyungsook An, Yun-Ja Cho, Geun-Cheol Lee, Yoosook Lee, Gynheung An and Pamela C Ronald

Linkage Disequilibrium-Based Quality Control for Large-Scale Genetic Studies pp. 1-9

Paul Scheet and Matthew Stephens

Volume 4, issue 7, 2008

Simultaneous Analysis of All SNPs in Genome-Wide and Re-Sequencing Association Studies pp. 1-8

Clive J Hoggart, John C Whittaker, Maria De Iorio and David J Balding

Tracing Sub-Structure in the European American Population with PCA-Informative Markers pp. 1-13

Peristera Paschou, Petros Drineas, Jamey Lewis, Caroline M Nievergelt, Deborah A Nickerson, Joshua D Smith, Paul M Ridker, Daniel I Chasman, Ronald M Krauss and Elad Ziv

Zebrafish Whole-Adult-Organism Chemogenomics for Large-Scale Predictive and Discovery Chemical Biology pp. 1-14

Siew Hong Lam, Sinnakarupan Mathavan, Yan Tong, Haixia Li, R Krishna Murthy Karuturi, Yilian Wu, Vinsensius B Vega, Edison T Liu and Zhiyuan Gong

An Integrated Approach for the Analysis of Biological Pathways using Mixed Models pp. 1-9

Lily Wang, Bing Zhang, Russell D Wolfinger and Xi Chen

Volume 4, issue 6, 2008

A Large-Scale Rheumatoid Arthritis Genetic Study Identifies Association at Chromosome 9q33.2 pp. 1-17

Monica Chang, Charles M Rowland, Veronica E Garcia, Steven J Schrodi, Joseph J Catanese, Annette H M van der Helm-van Mil, Kristin G Ardlie, Christopher I Amos, Lindsey A Criswell, Daniel L Kastner, Peter K Gregersen, Fina A S Kurreeman, Rene E M Toes, Tom W J Huizinga, Michael F Seldin and Ann B Begovich

Evaluating Statistical Methods Using Plasmode Data Sets in the Age of Massive Public Databases: An Illustration Using False Discovery Rates pp. 1-8

Gary L Gadbury, Qinfang Xiang, Lin Yang, Stephen Barnes, Grier P Page and David B Allison

Volume 4, issue 2, 2008

Notch Signalling Synchronizes the Zebrafish Segmentation Clock but Is Not Needed To Create Somite Boundaries pp. 1-11

Ertuğrul M Özbudak and Julian Lewis

Ready for Her Close-Up: An Interview with Elaine Strass pp. 1-4

Jane Gitschier

Volume 4, issue 1, 2008

Analysis and Application of European Genetic Substructure Using 300 K SNP Information pp. 1-11

Chao Tian, Robert M Plenge, Michael Ransom, Annette Lee, Pablo Villoslada, Carlo Selmi, Lars Klareskog, Ann E Pulver, Lihong Qi, Peter K Gregersen and Michael F Seldin

Volume 3, issue 12, 2007

Entropy Explains Aging, Genetic Determinism Explains Longevity, and Undefined Terminology Explains Misunderstanding Both pp. 1-1

Leonard Hayflick

Volume 3, issue 11, 2007

AGEMAP: A Gene Expression Database for Aging in Mice pp. 1-12

Jacob M Zahn, Suresh Poosala, Art B Owen, Donald K Ingram, Ana Lustig, Arnell Carter, Ashani T Weeraratna, Dennis D Taub, Myriam Gorospe, Krystyna Mazan-Mamczarz, Edward G Lakatta, Kenneth R Boheler, Xiangru Xu, Mark P Mattson, Geppino Falco, Minoru S H Ko, David Schlessinger, Jeffrey Firman, Sarah K Kummerfeld, William H Wood, Alan B Zonderman, Stuart K Kim and Kevin G Becker

Volume 3, issue 10, 2007

Regulatory Pathway Analysis by High-Throughput In Situ Hybridization pp. 1-17

Axel Visel, James Carson, Judit Oldekamp, Marei Warnecke, Vladimira Jakubcakova, Xunlei Zhou, Chad A Shaw, Gonzalo Alvarez-Bolado and Gregor Eichele

Volume 3, issue 9, 2007

Adaptive Evolution of Conserved Noncoding Elements in Mammals pp. 1-15

Su Yeon Kim and Jonathan K Pritchard

PCA-Correlated SNPs for Structure Identification in Worldwide Human Populations pp. 1-15

Peristera Paschou, Elad Ziv, Esteban G Burchard, Shweta Choudhry, William Rodriguez-Cintron, Michael W Mahoney and Petros Drineas

Gene Expression Programs of Human Smooth Muscle Cells: Tissue-Specific Differentiation and Prognostic Significance in Breast Cancers pp. 1-15

Jen-Tsan Chi, Edwin H Rodriguez, Zhen Wang, Dimitry S A Nuyten, Sayan Mukherjee, Matt van de Rijn, Marc J van de Vijver, Trevor Hastie and Patrick O Brown

Linkage Analysis of a Model Quantitative Trait in Humans: Finger Ridge Count Shows Significant Multivariate Linkage to 5q14.1 pp. 1-9

Sarah E Medland, Danuta Z Loesch, Bogdan Mdzewski, Gu Zhu, Grant W Montgomery and Nicholas G Martin

Capturing Heterogeneity in Gene Expression Studies by Surrogate Variable Analysis pp. 1-12

Jeffrey T Leek and John D Storey

Volume 3, issue 8, 2007

Assessing the Significance of Conserved Genomic Aberrations Using High Resolution Genomic Microarrays pp. 1-23

Mitchell Guttman, Carolyn Mies, Katarzyna Dudycz-Sulicz, Sharon J Diskin, Don A Baldwin, Christian J Stoeckert and Gregory R Grant

Volume 3, issue 6, 2007

A Genomic Pathway Approach to a Complex Disease: Axon Guidance and Parkinson Disease pp. 1-12

Timothy G Lesnick, Spiridon Papapetropoulos, Deborah C Mash, Jarlath Ffrench-Mullen, Lina Shehadeh, Mariza de Andrade, John R Henley, Walter A Rocca, J Eric Ahlskog and Demetrius M Maraganore

Volume 3, issue 5, 2007

A Method to Address Differential Bias in Genotyping in Large-Scale Association Studies pp. 1-9

Vincent Plagnol, Jason D Cooper, John A Todd and David G Clayton

Allele-Specific Chromatin Immunoprecipitation Studies Show Genetic Influence on Chromatin State in Human Genome pp. 1-11

Mitsutaka Kadota, Howard H Yang, Nan Hu, Chaoyu Wang, Ying Hu, Philip R Taylor, Kenneth H Buetow and Maxwell P Lee

Volume 3, issue 4, 2007

Generalized Analysis of Molecular Variance pp. 1-12

Caroline M Nievergelt, Ondrej Libiger and Nicholas J Schork

Genetic Structure of Chimpanzee Populations pp. 1-10

Celine Becquet, Nick Patterson, Anne C Stone, Molly Przeworski and David Reich

Volume 3, issue 3, 2007

Incorporating Single-Locus Tests into Haplotype Cladistic Analysis in Case-Control Studies pp. 1-10

Jianfeng Liu, Chris Papasian and Hong-Wen Deng

Volume 2, issue 12, 2006

Soft Sweeps III: The Signature of Positive Selection from Recurrent Mutation pp. 1-15

Pleuni S Pennings and Joachim Hermisson

Population Structure and Eigenanalysis pp. 1-20

Nick Patterson, Alkes L Price and David Reich

Volume 2, issue 11, 2006

Authors' Reply pp. 1-2

Erik van Nimwegen and Mihaela Zavolan

Volume 2, issue 8, 2006

Family-Based versus Unrelated Case-Control Designs for Genetic Associations pp. 1-9

Evangelos Evangelou, Thomas A Trikalinos, Georgia Salanti and John P A Ioannidis

Are Molecular Haplotypes Worth the Time and Expense? A Cost-Effective Method for Applying Molecular Haplotypes pp. 1-11

Mark A Levenstien, Jürg Ott and Derek Gordon

Volume 2, issue 7, 2006

Possible Ancestral Structure in Human Populations pp. 1-8

Vincent Plagnol and Jeffrey D Wall

Structural Model Analysis of Multiple Quantitative Traits pp. 1-12

Renhua Li, Shirng-Wern Tsaih, Keith Shockley, Ioannis M Stylianou, Jon Wergedal, Beverly Paigen and Gary A Churchill

Anatomic Demarcation by Positional Variation in Fibroblast Gene Expression Programs pp. 1-13

John L Rinn, Chanda Bondre, Hayes B Gladstone, Patrick O Brown and Howard Y Chang

Volume 2, issue 6, 2006

The Making of a President: An Interview with Shirley Tilghman pp. 1-4

Jane Gitschier

Volume 2, issue 5, 2006

High-Resolution Recombination Patterns in a Region of Human Chromosome 21 Measured by Sperm Typing pp. 1-11

Irene Tiemann-Boege, Peter Calabrese, David M Cochran, Rebecca Sokol and Norman Arnheim

Volume 2, issue 4, 2006

Mice and Men: Their Promoter Properties pp. 1-13

Vladimir B Bajic, Sin Lam Tan, Alan Christoffels, Christian Schönbach, Leonard Lipovich, Liang Yang, Oliver Hofmann, Adele Kruger, Winston Hide, Chikatoshi Kai, Jun Kawai, David A Hume, Piero Carninci and Yoshihide Hayashizaki

Volume 2, issue 3, 2006

The Dictyostelium Kinome—Analysis of the Protein Kinases from a Simple Model Organism pp. 1-13

Jonathan M Goldberg, Gerard Manning, Allen Liu, Petra Fey, Karen E Pilcher, Yanji Xu and Janet L Smith

CpG Island Methylation in Human Lymphocytes Is Highly Correlated with DNA Sequence, Repeats, and Predicted DNA Structure pp. 1-10

Christoph Bock, Martina Paulsen, Sascha Tierling, Thomas Mikeska, Thomas Lengauer and Jörn Walter

Volume 2, issue 2, 2006

DNA Sequences Shaped by Selection for Stability pp. 1-7

Martin Ackermann and Lin Chao

An Integrated Strategy for Analyzing the Unique Developmental Programs of Different Myoblast Subtypes pp. 1-12

Beatriz Estrada, Sung E Choe, Stephen S Gisselbrecht, Sebastien Michaud, Lakshmi Raj, Brian W Busser, Marc S Halfon, George M Church and Alan M Michelson

Volume 1, issue 6, 2005

Species Choice for Comparative Genomics: Being Greedy Works pp. 1-1

Fabio Pardi and Nick Goldman

Clines, Clusters, and the Effect of Study Design on the Inference of Human Population Structure pp. 1-12

Noah A Rosenberg, Saurabh Mahajan, Sohini Ramachandran, Chengfeng Zhao, Jonathan K Pritchard and Marcus W Feldman

Volume 1, issue 1, 2005

Diversity of Flowering Responses in Wild Arabidopsis thaliana Strains pp. 1-

Janne Lempe, Sureshkumar Balasubramanian, Sridevi Sureshkumar, Anandita Singh, Markus Schmid and Detlef Weigel