PLOS Genetics

2005 - 2025

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Volume 5, issue 12, 2009

A Genome-Wide Association Study Reveals Variants in ARL15 that Influence Adiponectin Levels pp. 1-10

J Brent Richards, Dawn Waterworth, Stephen O'Rahilly, Marie-France Hivert, Ruth J F Loos, John R B Perry, Toshiko Tanaka, Nicholas John Timpson, Robert K Semple, Nicole Soranzo, Kijoung Song, Nuno Rocha, Elin Grundberg, Josée Dupuis, Jose C Florez, Claudia Langenberg, Inga Prokopenko, Richa Saxena, Robert Sladek, Yurii Aulchenko, David Evans, Gerard Waeber, Jeanette Erdmann, Mary-Susan Burnett, Naveed Sattar, Joseph Devaney, Christina Willenborg, Aroon Hingorani, Jaquelin C M Witteman, Peter Vollenweider, Beate Glaser, Christian Hengstenberg, Luigi Ferrucci, David Melzer, Klaus Stark, John Deanfield, Janina Winogradow, Martina Grassl, Alistair S Hall, Josephine M Egan, John R Thompson, Sally L Ricketts, Inke R König, Wibke Reinhard, Scott Grundy, H-Erich Wichmann, Phil Barter, Robert Mahley, Y Antero Kesaniemi, Daniel J Rader, Muredach P Reilly, Stephen E Epstein, Alexandre F R Stewart, Cornelia M Van Duijn, Heribert Schunkert, Keith Burling, Panos Deloukas, Tomi Pastinen, Nilesh J Samani, Ruth McPherson, George Davey Smith, Timothy M Frayling, Nicholas J Wareham, James B Meigs, Vincent Mooser, Tim D Spector and Consortium Giant

Volume 5, issue 11, 2009

On the Analysis of Genome-Wide Association Studies in Family-Based Designs: A Universal, Robust Analysis Approach and an Application to Four Genome-Wide Association Studies pp. 1-9

Sungho Won, Jemma B Wilk, Rasika A Mathias, Christopher J O'Donnell, Edwin K Silverman, Kathleen Barnes, George T O'Connor, Scott T Weiss and Christoph Lange

Volume 5, issue 10, 2009

A Genealogical Interpretation of Principal Components Analysis pp. 1-10

Gil McVean

Meta-Analysis of the INSIG2 Association with Obesity Including 74,345 Individuals: Does Heterogeneity of Estimates Relate to Study Design? pp. 1-10

Iris M Heid, Cornelia Huth, Ruth J F Loos, Florian Kronenberg, Vera Adamkova, Sonia S Anand, Kristin Ardlie, Heike Biebermann, Peter Bjerregaard, Heiner Boeing, Claude Bouchard, Marina Ciullo, Jackie A Cooper, Dolores Corella, Christian Dina, James C Engert, Eva Fisher, Francesc Francès, Philippe Froguel, Johannes Hebebrand, Robert A Hegele, Anke Hinney, Margret R Hoehe, Frank B Hu, Jaroslav A Hubacek, Steve E Humphries, Steven C Hunt, Thomas Illig, Marjo-Riita Järvelin, Marika Kaakinen, Barbara Kollerits, Heiko Krude, Jitender Kumar, Leslie A Lange, Birgit Langer, Shengxu Li, Andreas Luchner, Helen N Lyon, David Meyre, Karen L Mohlke, Vincent Mooser, Almut Nebel, Thuy Trang Nguyen, Bernhard Paulweber, Louis Perusse, Lu Qi, Tuomo Rankinen, Dieter Rosskopf, Stefan Schreiber, Shantanu Sengupta, Rossella Sorice, Anita Suk, Gudmar Thorleifsson, Unnur Thorsteinsdottir, Henry Völzke, Karani S Vimaleswaran, Nicholas J Wareham, Dawn Waterworth, Salim Yusuf, Cecilia Lindgren, Mark I McCarthy, Christoph Lange, Joel N Hirschhorn, Nan Laird and H-Erich Wichmann

Needles in the Haystack: Identifying Individuals Present in Pooled Genomic Data pp. 1-8

Rosemary Braun, William Rowe, Carl Schaefer, Jinghui Zhang and Kenneth Buetow

From Disease Association to Risk Assessment: An Optimistic View from Genome-Wide Association Studies on Type 1 Diabetes pp. 1-11

Zhi Wei, Kai Wang, Hui-Qi Qu, Haitao Zhang, Jonathan Bradfield, Cecilia Kim, Edward Frackleton, Cuiping Hou, Joseph T Glessner, Rosetta Chiavacci, Charles Stanley, Dimitri Monos, Struan F A Grant, Constantin Polychronakos and Hakon Hakonarson

The Limits of Individual Identification from Sample Allele Frequencies: Theory and Statistical Analysis pp. 1-6

Peter M Visscher and William G Hill

Volume 5, issue 9, 2009

A Genome-Wide Association Analysis Identified a Novel Susceptible Locus for Pathological Myopia at 11q24.1 pp. 1-7

Hideo Nakanishi, Ryo Yamada, Norimoto Gotoh, Hisako Hayashi, Kenji Yamashiro, Noriaki Shimada, Kyoko Ohno-Matsui, Manabu Mochizuki, Masaaki Saito, Tomohiro Iida, Keitaro Matsuo, Kazuo Tajima, Nagahisa Yoshimura and Fumihiko Matsuda

Volume 5, issue 7, 2009

Scientists←Editors←Scientists: The Past, Present, and Future of PLoS Genetics pp. 1-2

Gregory S Barsh and Gregory P Copenhaver

Statistical Power of Model Selection Strategies for Genome-Wide Association Studies pp. 1-14

Zheyang Wu and Hongyu Zhao

EPHA2 Is Associated with Age-Related Cortical Cataract in Mice and Humans pp. 1-19

Gyungah Jun, Hong Guo, Barbara E K Klein, Ronald Klein, Jie Jin Wang, Paul Mitchell, Hui Miao, Kristine E Lee, Tripti Joshi, Matthias Buck, Preeti Chugha, David Bardenstein, Alison P Klein, Joan E Bailey-Wilson, Xiaohua Gong, Tim D Spector, Toby Andrew, Christopher J Hammond, Robert C Elston, Sudha K Iyengar and Bingcheng Wang

On Quality Control Measures in Genome-Wide Association Studies: A Test to Assess the Genotyping Quality of Individual Probands in Family-Based Association Studies and an Application to the HapMap Data pp. 1-11

David W Fardo, Iuliana Ionita-Laza and Christoph Lange

Enhanced Disease Susceptibility 1 and Salicylic Acid Act Redundantly to Regulate Resistance Gene-Mediated Signaling pp. 1-18

Srivathsa C Venugopal, Rae-Dong Jeong, Mihir K Mandal, Shifeng Zhu, A C Chandra-Shekara, Ye Xia, Matthew Hersh, Arnold J Stromberg, DuRoy Navarre, Aardra Kachroo and Pradeep Kachroo

Volume 5, issue 6, 2009

NRXN3 Is a Novel Locus for Waist Circumference: A Genome-Wide Association Study from the CHARGE Consortium pp. 1-9

Nancy L Heard-Costa, M Carola Zillikens, Keri L Monda, Åsa Johansson, Tamara B Harris, Mao Fu, Talin Haritunians, Mary F Feitosa, Thor Aspelund, Gudny Eiriksdottir, Melissa Garcia, Lenore J Launer, Albert V Smith, Braxton D Mitchell, Patrick F McArdle, Alan R Shuldiner, Suzette J Bielinski, Eric Boerwinkle, Fred Brancati, Ellen W Demerath, James S Pankow, Alice M Arnold, Yii- Der Ida Chen, Nicole L Glazer, Barbara McKnight, Bruce M Psaty, Jerome I Rotter, Najaf Amin, Harry Campbell, Ulf Gyllensten, Cristian Pattaro, Peter P Pramstaller, Igor Rudan, Maksim Struchalin, Veronique Vitart, Xiaoyi Gao, Aldi Kraja, Michael A Province, Qunyuan Zhang, Larry D Atwood, Josée Dupuis, Joel N Hirschhorn, Cashell E Jaquish, Christopher J O'Donnell, Ramachandran S Vasan, Charles C White, Yurii S Aulchenko, Karol Estrada, Albert Hofman, Fernando Rivadeneira, André G Uitterlinden, Jacqueline C M Witteman, Ben A Oostra, Robert C Kaplan, Vilmundur Gudnason, Jeffrey R O'Connell, Ingrid B Borecki, Cornelia M van Duijn, L Adrienne Cupples, Caroline S Fox and Kari E North

Genome-Wide Association Scan Meta-Analysis Identifies Three Loci Influencing Adiposity and Fat Distribution pp. 1-13

Cecilia M Lindgren, Iris M Heid, Joshua C Randall, Claudia Lamina, Valgerdur Steinthorsdottir, Lu Qi, Elizabeth K Speliotes, Gudmar Thorleifsson, Cristen J Willer, Blanca M Herrera, Anne U Jackson, Noha Lim, Paul Scheet, Nicole Soranzo, Najaf Amin, Yurii S Aulchenko, John C Chambers, Alexander Drong, Jian'an Luan, Helen N Lyon, Fernando Rivadeneira, Serena Sanna, Nicholas J Timpson, M Carola Zillikens, Jing Hua Zhao, Peter Almgren, Stefania Bandinelli, Amanda J Bennett, Richard N Bergman, Lori L Bonnycastle, Suzannah J Bumpstead, Stephen J Chanock, Lynn Cherkas, Peter Chines, Lachlan Coin, Cyrus Cooper, Gabriel Crawford, Angela Doering, Anna Dominiczak, Alex S F Doney, Shah Ebrahim, Paul Elliott, Michael R Erdos, Karol Estrada, Luigi Ferrucci, Guido Fischer, Nita G Forouhi, Christian Gieger, Harald Grallert, Christopher J Groves, Scott Grundy, Candace Guiducci, David Hadley, Anders Hamsten, Aki S Havulinna, Albert Hofman, Rolf Holle, John W Holloway, Thomas Illig, Bo Isomaa, Leonie C Jacobs, Karen Jameson, Pekka Jousilahti, Fredrik Karpe, Johanna Kuusisto, Jaana Laitinen, G Mark Lathrop, Debbie A Lawlor, Massimo Mangino, Wendy L McArdle, Thomas Meitinger, Mario A Morken, Andrew P Morris, Patricia Munroe, Narisu Narisu, Anna Nordström, Peter Nordström, Ben A Oostra, Colin N A Palmer, Felicity Payne, John F Peden, Inga Prokopenko, Frida Renström, Aimo Ruokonen, Veikko Salomaa, Manjinder S Sandhu, Laura J Scott, Angelo Scuteri, Kaisa Silander, Kijoung Song, Xin Yuan, Heather M Stringham, Amy J Swift, Tiinamaija Tuomi, Manuela Uda, Peter Vollenweider, Gerard Waeber, Chris Wallace, G Bragi Walters, Michael N Weedon, The Wellcome Trust Case Control Consortium, Jacqueline C M Witteman, Cuilin Zhang, Weihua Zhang, Mark J Caulfield, Francis S Collins, George Davey Smith, Ian N M Day, Paul W Franks, Andrew T Hattersley, Frank B Hu, Marjo-Riitta Jarvelin, Augustine Kong, Jaspal S Kooner, Markku Laakso, Edward Lakatta, Vincent Mooser, Andrew D Morris, Leena Peltonen, Nilesh J Samani, Timothy D Spector, David P Strachan, Toshiko Tanaka, Jaakko Tuomilehto, André G Uitterlinden, Cornelia M van Duijn, Nicholas J Wareham, Hugh Watkins for the PROCARDIS Consortia, Dawn M Waterworth, Michael Boehnke, Panos Deloukas, Leif Groop, David J Hunter, Unnur Thorsteinsdottir, David Schlessinger, H-Erich Wichmann, Timothy M Frayling, Gonçalo R Abecasis, Joel N Hirschhorn, Ruth J F Loos, Kari Stefansson, Karen L Mohlke, Inês Barroso and Mark I McCarthy for the GIANT Consortium

A Flexible and Accurate Genotype Imputation Method for the Next Generation of Genome-Wide Association Studies pp. 1-15

Bryan N Howie, Peter Donnelly and Jonathan Marchini

Identifying Relationships among Genomic Disease Regions: Predicting Genes at Pathogenic SNP Associations and Rare Deletions pp. 1-15

Soumya Raychaudhuri, Robert M Plenge, Elizabeth J Rossin, Aylwin C Y Ng, International Schizophrenia Consortium, Shaun M Purcell, Pamela Sklar, Edward M Scolnick, Ramnik J Xavier, David Altshuler and Mark J Daly

Meta-Analysis of 28,141 Individuals Identifies Common Variants within Five New Loci That Influence Uric Acid Concentrations pp. 1-10

Melanie Kolz, Toby Johnson, Serena Sanna, Alexander Teumer, Veronique Vitart, Markus Perola, Massimo Mangino, Eva Albrecht, Chris Wallace, Martin Farrall, Åsa Johansson, Dale R Nyholt, Yurii Aulchenko, Jacques S Beckmann, Sven Bergmann, Murielle Bochud, Morris Brown, Harry Campbell, for the EUROSPAN Consortium, John Connell, Anna Dominiczak, Georg Homuth, Claudia Lamina, Mark I McCarthy, for the ENGAGE Consortium, Thomas Meitinger, Vincent Mooser, Patricia Munroe, Matthias Nauck, John Peden, Holger Prokisch, Perttu Salo, Veikko Salomaa, Nilesh J Samani, David Schlessinger, Manuela Uda, Uwe Völker, Gérard Waeber, Dawn Waterworth, Rui Wang-Sattler, Alan F Wright, Jerzy Adamski, John B Whitfield, Ulf Gyllensten, James F Wilson, Igor Rudan, Peter Pramstaller, Hugh Watkins, for the PROCARDIS Consortium, Angela Doering, H-Erich Wichmann, for the KORA Study, Tim D Spector, Leena Peltonen, Henry Völzke, Ramaiah Nagaraja, Peter Vollenweider, Mark Caulfield, For The Wtccc, Thomas Illig and Christian Gieger

The Impact of Divergence Time on the Nature of Population Structure: An Example from Iceland pp. 1-10

Alkes L Price, Agnar Helgason, Snaebjorn Palsson, Hreinn Stefansson, David St. Clair, Ole A Andreassen, David Reich, Augustine Kong and Kari Stefansson

Volume 5, issue 5, 2009

Epistatic Module Detection for Case-Control Studies: A Bayesian Model with a Gibbs Sampling Strategy pp. 1-18

Wanwan Tang, Xuebing Wu, Rui Jiang and Yanda Li

Modulated Modularity Clustering as an Exploratory Tool for Functional Genomic Inference pp. 1-13

Eric A Stone and Julien F Ayroles

Volume 5, issue 4, 2009

Meta-Analysis of Genome-Wide Scans for Human Adult Stature Identifies Novel Loci and Associations with Measures of Skeletal Frame Size pp. 1-13

Nicole Soranzo, Fernando Rivadeneira, Usha Chinappen-Horsley, Ida Malkina, J Brent Richards, Naomi Hammond, Lisette Stolk, Alexandra Nica, Michael Inouye, Albert Hofman, Jonathan Stephens, Eleanor Wheeler, Pascal Arp, Rhian Gwilliam, P Mila Jhamai, Simon Potter, Amy Chaney, Mohammed J R Ghori, Radhi Ravindrarajah, Sergey Ermakov, Karol Estrada, Huibert A P Pols, Frances M Williams, Wendy L McArdle, Joyce B van Meurs, Ruth J F Loos, Emmanouil T Dermitzakis, Kourosh R Ahmadi, Deborah J Hart, Willem H Ouwehand, Nicholas J Wareham, Inês Barroso, Manjinder S Sandhu, David P Strachan, Gregory Livshits, Timothy D Spector, André G Uitterlinden and Panos Deloukas

Rapid and Accurate Multiple Testing Correction and Power Estimation for Millions of Correlated Markers pp. 1-13

Buhm Han, Hyun Min Kang and Eleazar Eskin

Volume 5, issue 3, 2009

A Genome-Wide Association Study Confirms VKORC1, CYP2C9, and CYP4F2 as Principal Genetic Determinants of Warfarin Dose pp. 1-9

Fumihiko Takeuchi, Ralph McGinnis, Stephane Bourgeois, Chris Barnes, Niclas Eriksson, Nicole Soranzo, Pamela Whittaker, Venkatesh Ranganath, Vasudev Kumanduri, William McLaren, Lennart Holm, Jonatan Lindh, Anders Rane, Mia Wadelius and Panos Deloukas

Rapid Pathway Evolution Facilitated by Horizontal Gene Transfers across Prokaryotic Lineages pp. 1-8

Wataru Iwasaki and Toshihisa Takagi

The Distribution of Fitness Effects of Beneficial Mutations in Pseudomonas aeruginosa pp. 1-7

R Craig MacLean and Angus Buckling

Measures of Autozygosity in Decline: Globalization, Urbanization, and Its Implications for Medical Genetics pp. 1-7

Michael A Nalls, Javier Simon-Sanchez, J Raphael Gibbs, Coro Paisan-Ruiz, Jose Tomas Bras, Toshiko Tanaka, Mar Matarin, Sonja Scholz, Charles Weitz, Tamara B Harris, Luigi Ferrucci, John Hardy and Andrew B Singleton

Volume 5, issue 1, 2009

IL2RA Genetic Heterogeneity in Multiple Sclerosis and Type 1 Diabetes Susceptibility and Soluble Interleukin-2 Receptor Production pp. 1-8

Lisa M Maier, Christopher E Lowe, Jason Cooper, Kate Downes, David E Anderson, Christopher Severson, Pamela M Clark, Brian Healy, Neil Walker, Cristin Aubin, Jorge R Oksenberg, Stephen L Hauser, Alistair Compston, Stephen Sawcer, The International Multiple Sclerosis Genetics Consortium, Philip L De Jager, Linda S Wicker, John A Todd and David A Hafler

Volume 4, issue 12, 2008

Practical Issues in Imputation-Based Association Mapping pp. 1-11

Yongtao Guan and Matthew Stephens

The Population Genetics of dN/dS pp. 1-10

Sergey Kryazhimskiy and Joshua B Plotkin

Volume 4, issue 11, 2008

Genetic Analysis of Human Traits In Vitro: Drug Response and Gene Expression in Lymphoblastoid Cell Lines pp. 1-16

Edwin Choy, Roman Yelensky, Sasha Bonakdar, Robert M Plenge, Richa Saxena, Philip L De Jager, Stanley Y Shaw, Cara S Wolfish, Jacqueline M Slavik, Chris Cotsapas, Manuel Rivas, Emmanouil T Dermitzakis, Ellen Cahir-McFarland, Elliott Kieff, David Hafler, Mark J Daly and David Altshuler

Volume 4, issue 10, 2008

Efficient and Accurate Construction of Genetic Linkage Maps from the Minimum Spanning Tree of a Graph pp. 1-11

Yonghui Wu, Prasanna R Bhat, Timothy J Close and Stefano Lonardi

Volume 4, issue 9, 2008

A Review of Family-Based Tests for Linkage Disequilibrium between a Quantitative Trait and a Genetic Marker pp. 1-6

Warren J Ewens, Mingyao Li and Richard S Spielman

Screening and Replication using the Same Data Set: Testing Strategies for Family-Based Studies in which All Probands Are Affected pp. 1-10

Amy Murphy, Scott T Weiss and Christoph Lange

Volume 4, issue 8, 2008

Linkage Disequilibrium-Based Quality Control for Large-Scale Genetic Studies pp. 1-9

Paul Scheet and Matthew Stephens

A Tribute to Evgenii V. Ananiev, 1947–2008 pp. 1-3

Sergei M Mirkin

Identification and Functional Analysis of Light-Responsive Unique Genes and Gene Family Members in Rice pp. 1-19

Ki-Hong Jung, Jinwon Lee, Chris Dardick, Young-Su Seo, Peijian Cao, Patrick Canlas, Jirapa Phetsom, Xia Xu, Shu Ouyang, Kyungsook An, Yun-Ja Cho, Geun-Cheol Lee, Yoosook Lee, Gynheung An and Pamela C Ronald

Volume 4, issue 7, 2008

Simultaneous Analysis of All SNPs in Genome-Wide and Re-Sequencing Association Studies pp. 1-8

Clive J Hoggart, John C Whittaker, Maria De Iorio and David J Balding

Tracing Sub-Structure in the European American Population with PCA-Informative Markers pp. 1-13

Peristera Paschou, Petros Drineas, Jamey Lewis, Caroline M Nievergelt, Deborah A Nickerson, Joshua D Smith, Paul M Ridker, Daniel I Chasman, Ronald M Krauss and Elad Ziv

Zebrafish Whole-Adult-Organism Chemogenomics for Large-Scale Predictive and Discovery Chemical Biology pp. 1-14

Siew Hong Lam, Sinnakarupan Mathavan, Yan Tong, Haixia Li, R Krishna Murthy Karuturi, Yilian Wu, Vinsensius B Vega, Edison T Liu and Zhiyuan Gong

An Integrated Approach for the Analysis of Biological Pathways using Mixed Models pp. 1-9

Lily Wang, Bing Zhang, Russell D Wolfinger and Xi Chen

Volume 4, issue 6, 2008

Evaluating Statistical Methods Using Plasmode Data Sets in the Age of Massive Public Databases: An Illustration Using False Discovery Rates pp. 1-8

Gary L Gadbury, Qinfang Xiang, Lin Yang, Stephen Barnes, Grier P Page and David B Allison

A Large-Scale Rheumatoid Arthritis Genetic Study Identifies Association at Chromosome 9q33.2 pp. 1-17

Monica Chang, Charles M Rowland, Veronica E Garcia, Steven J Schrodi, Joseph J Catanese, Annette H M van der Helm-van Mil, Kristin G Ardlie, Christopher I Amos, Lindsey A Criswell, Daniel L Kastner, Peter K Gregersen, Fina A S Kurreeman, Rene E M Toes, Tom W J Huizinga, Michael F Seldin and Ann B Begovich

Volume 4, issue 2, 2008

Ready for Her Close-Up: An Interview with Elaine Strass pp. 1-4

Jane Gitschier

Notch Signalling Synchronizes the Zebrafish Segmentation Clock but Is Not Needed To Create Somite Boundaries pp. 1-11

Ertuğrul M Özbudak and Julian Lewis

Volume 4, issue 1, 2008

Analysis and Application of European Genetic Substructure Using 300 K SNP Information pp. 1-11

Chao Tian, Robert M Plenge, Michael Ransom, Annette Lee, Pablo Villoslada, Carlo Selmi, Lars Klareskog, Ann E Pulver, Lihong Qi, Peter K Gregersen and Michael F Seldin

Volume 3, issue 12, 2007

Entropy Explains Aging, Genetic Determinism Explains Longevity, and Undefined Terminology Explains Misunderstanding Both pp. 1-1

Leonard Hayflick

Volume 3, issue 11, 2007

AGEMAP: A Gene Expression Database for Aging in Mice pp. 1-12

Jacob M Zahn, Suresh Poosala, Art B Owen, Donald K Ingram, Ana Lustig, Arnell Carter, Ashani T Weeraratna, Dennis D Taub, Myriam Gorospe, Krystyna Mazan-Mamczarz, Edward G Lakatta, Kenneth R Boheler, Xiangru Xu, Mark P Mattson, Geppino Falco, Minoru S H Ko, David Schlessinger, Jeffrey Firman, Sarah K Kummerfeld, William H Wood, Alan B Zonderman, Stuart K Kim and Kevin G Becker

Volume 3, issue 10, 2007

Regulatory Pathway Analysis by High-Throughput In Situ Hybridization pp. 1-17

Axel Visel, James Carson, Judit Oldekamp, Marei Warnecke, Vladimira Jakubcakova, Xunlei Zhou, Chad A Shaw, Gonzalo Alvarez-Bolado and Gregor Eichele

Volume 3, issue 9, 2007

Linkage Analysis of a Model Quantitative Trait in Humans: Finger Ridge Count Shows Significant Multivariate Linkage to 5q14.1 pp. 1-9

Sarah E Medland, Danuta Z Loesch, Bogdan Mdzewski, Gu Zhu, Grant W Montgomery and Nicholas G Martin

Adaptive Evolution of Conserved Noncoding Elements in Mammals pp. 1-15

Su Yeon Kim and Jonathan K Pritchard

PCA-Correlated SNPs for Structure Identification in Worldwide Human Populations pp. 1-15

Peristera Paschou, Elad Ziv, Esteban G Burchard, Shweta Choudhry, William Rodriguez-Cintron, Michael W Mahoney and Petros Drineas

Gene Expression Programs of Human Smooth Muscle Cells: Tissue-Specific Differentiation and Prognostic Significance in Breast Cancers pp. 1-15

Jen-Tsan Chi, Edwin H Rodriguez, Zhen Wang, Dimitry S A Nuyten, Sayan Mukherjee, Matt van de Rijn, Marc J van de Vijver, Trevor Hastie and Patrick O Brown

Capturing Heterogeneity in Gene Expression Studies by Surrogate Variable Analysis pp. 1-12

Jeffrey T Leek and John D Storey

Volume 3, issue 8, 2007

Assessing the Significance of Conserved Genomic Aberrations Using High Resolution Genomic Microarrays pp. 1-23

Mitchell Guttman, Carolyn Mies, Katarzyna Dudycz-Sulicz, Sharon J Diskin, Don A Baldwin, Christian J Stoeckert and Gregory R Grant

Volume 3, issue 6, 2007

A Genomic Pathway Approach to a Complex Disease: Axon Guidance and Parkinson Disease pp. 1-12

Timothy G Lesnick, Spiridon Papapetropoulos, Deborah C Mash, Jarlath Ffrench-Mullen, Lina Shehadeh, Mariza de Andrade, John R Henley, Walter A Rocca, J Eric Ahlskog and Demetrius M Maraganore

Volume 3, issue 5, 2007

Allele-Specific Chromatin Immunoprecipitation Studies Show Genetic Influence on Chromatin State in Human Genome pp. 1-11

Mitsutaka Kadota, Howard H Yang, Nan Hu, Chaoyu Wang, Ying Hu, Philip R Taylor, Kenneth H Buetow and Maxwell P Lee

A Method to Address Differential Bias in Genotyping in Large-Scale Association Studies pp. 1-9

Vincent Plagnol, Jason D Cooper, John A Todd and David G Clayton

Volume 3, issue 4, 2007

Genetic Structure of Chimpanzee Populations pp. 1-10

Celine Becquet, Nick Patterson, Anne C Stone, Molly Przeworski and David Reich

Generalized Analysis of Molecular Variance pp. 1-12

Caroline M Nievergelt, Ondrej Libiger and Nicholas J Schork

Volume 3, issue 3, 2007

Incorporating Single-Locus Tests into Haplotype Cladistic Analysis in Case-Control Studies pp. 1-10

Jianfeng Liu, Chris Papasian and Hong-Wen Deng