PLOS Medicine

2004 - 2022

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Volume 7, issue 12, 2010

Clinical Benefits, Costs, and Cost-Effectiveness of Neonatal Intensive Care in Mexico pp. 1-10

Jochen Profit, Diana Lee, John A Zupancic, LuAnn Papile, Cristina Gutierrez, Sue J Goldie, Eduardo Gonzalez-Pier and Joshua A Salomon

Tuberculosis Incidence in Prisons: A Systematic Review pp. 1-10

Iacopo Baussano, Brian G Williams, Paul Nunn, Marta Beggiato, Ugo Fedeli and Fabio Scano

Scaling Up the 2010 World Health Organization HIV Treatment Guidelines in Resource-Limited Settings: A Model-Based Analysis pp. 1-12

Rochelle P Walensky, Robin Wood, Andrea L Ciaranello, A David Paltiel, Sarah B Lorenzana, Xavier Anglaret, Adam W Stoler, Kenneth A Freedberg and for the CEPAC-International Investigators

Association of Secondhand Smoke Exposure with Pediatric Invasive Bacterial Disease and Bacterial Carriage: A Systematic Review and Meta-analysis pp. 1-14

Chien-Chang Lee, Nicole A Middaugh, Stephen R C Howie and Majid Ezzati

Toward a Consensus on Guiding Principles for Health Systems Strengthening pp. 1-6

Robert C Swanson, Annette Bongiovanni, Elizabeth Bradley, Varnee Murugan, Jesper Sundewall, Arvind Betigeri, Frank Nyonator, Adriano Cattaneo, Brandi Harless, Andrey Ostrovsky and Ronald Labonté

The Health Crisis of Tuberculosis in Prisons Extends beyond the Prison Walls pp. 1-2

The PLoS Medicine Editors

Participatory Epidemiology: Use of Mobile Phones for Community-Based Health Reporting pp. 1-5

Clark C Freifeld, Rumi Chunara, Sumiko R Mekaru, Emily H Chan, Taha Kass-Hout, Anahi Ayala Iacucci and John S Brownstein

Volume 7, issue 11, 2010

Strategies for Increasing Recruitment to Randomised Controlled Trials: Systematic Review pp. 1-16

Patrina H Y Caldwell, Sana Hamilton, Alvin Tan and Jonathan C Craig

Prescription Medicines and the Risk of Road Traffic Crashes: A French Registry-Based Study pp. 1-10

Ludivine Orriols, Bernard Delorme, Blandine Gadegbeku, Aurore Tricotel, Benjamin Contrand, Bernard Laumon, Louis-Rachid Salmi, Emmanuel Lagarde and on behalf of the CESIR research Group

Sanitation and Health pp. 1-7

Duncan Mara, Jon Lane, Beth Scott and David Trouba

Defining Research to Improve Health Systems pp. 1-7

Jan H F Remme, Taghreed Adam, Francisco Becerra-Posada, Catherine D'Arcangues, Michael Devlin, Charles Gardner, Abdul Ghaffar, Joachim Hombach, Jane F K Kengeya, Anthony Mbewu, Michael T Mbizvo, Zafar Mirza, Tikki Pang, Robert G Ridley, Fabio Zicker and Robert F Terry

WHO and Global Health Monitoring: The Way Forward pp. 1-3

J Ties Boerma, Colin Mathers and Carla Abou-Zahr

Which Path to Universal Health Coverage? Perspectives on the World Health Report 2010 pp. 1-3

Sara Bennett, Sachiko Ozawa and Krishna D Rao

Production and Analysis of Health Indicators: The Role of Academia pp. 1-3

Christopher J L Murray and Alan D Lopez

The Imperfect World of Global Health Estimates pp. 1-3

Peter Byass

Why Do Evaluations of eHealth Programs Fail? An Alternative Set of Guiding Principles pp. 1-5

Trisha Greenhalgh and Jill Russell

Doctors and Drug Companies: Still Cozy after All These Years pp. 1-2

David Henry

Global Health Estimates: Stronger Collaboration Needed with Low- and Middle-Income Countries pp. 1-2

Osman Sankoh

Combining Domestic and Foreign Investment to Expand Tuberculosis Control in China pp. 1-6

Zhong-wei Jia, Shi-ming Cheng, Zhi-jun Li, Xin Du, Fei Huang, Xiao-wei Jia, Peng Kong, Yun-xi Liu, Wei Chen, Wei Wang and Christopher Dye

Volume 7, issue 10, 2010

Oral Ondansetron Administration in Emergency Departments to Children with Gastroenteritis: An Economic Analysis pp. 1-10

Stephen B Freedman, Michael J Steiner and Kevin J Chan

Editors, Publishers, Impact Factors, and Reprint Income pp. 1-2

Harvey Marcovitch

An Urgent Need to Restrict Access to Pesticides Based on Human Lethality pp. 1-2

Matthew Miller and Kavi Bhalla

Increased Responsibility and Transparency in an Era of Increased Visibility pp. 1-2

The PLoS Medicine Editors

The Persisting Burden of Intracerebral Haemorrhage: Can Effective Treatments Be Found? pp. 1-6

Colin B Josephson, Joseph Frantzias, Neshika Samarasekera and Rustam Al-Shahi Salman

Conflicts of Interest at Medical Journals: The Influence of Industry-Supported Randomised Trials on Journal Impact Factors and Revenue – Cohort Study pp. 1-7

Andreas Lundh, Marija Barbateskovic, Asbjørn Hróbjartsson and Peter C Gøtzsche

Volume 7, issue 9, 2010

Combined Impact of Lifestyle-Related Factors on Total and Cause-Specific Mortality among Chinese Women: Prospective Cohort Study pp. 1-11

Sarah J Nechuta, Xiao-Ou Shu, Hong-Lan Li, Gong Yang, Yong-Bing Xiang, Hui Cai, Wong-Ho Chow, Butian Ji, Xianglan Zhang, Wanqing Wen, Yu-Tang Gao and Wei Zheng

Persistence with Statins and Onset of Rheumatoid Arthritis: A Population-Based Cohort Study pp. 1-13

Gabriel Chodick, Howard Amital, Yoav Shalem, Ehud Kokia, Anthony D Heymann, Avi Porath and Varda Shalev

Cost-Effectiveness of Pooled Nucleic Acid Amplification Testing for Acute HIV Infection after Third-Generation HIV Antibody Screening and Rapid Testing in the United States: A Comparison of Three Public Health Settings pp. 1-10

Angela B Hutchinson, Pragna Patel, Stephanie L Sansom, Paul G Farnham, Timothy J Sullivan, Berry Bennett, Peter R Kerndt, Robert K Bolan, James D Heffelfinger, Vimalanand S Prabhu and Bernard M Branson

Examining the “Urban Advantage” in Maternal Health Care in Developing Countries pp. 1-7

Zoë Matthews, Amos Channon, Sarah Neal, David Osrin, Nyovani Madise and William Stones

Are Drug Companies Living Up to Their Human Rights Responsibilities? Moving Toward Assessment pp. 1-3

Sofia Gruskin and Zyde Raad

Are Drug Companies Living Up to Their Human Rights Responsibilities? The Perspective of the Former United Nations Special Rapporteur (2002-2008) pp. 1-3

Paul Hunt and Rajat Khosla

Radiodiagnostic Imaging in Pregnancy and the Risk of Childhood Malignancy: Raising the Bar pp. 1-3

Eduardo L Franco and Guy-Anne Turgeon

Does It Matter Who Writes Medical News Stories? pp. 1-5

Amanda Wilson, Jane Robertson, Patrick McElduff, Alison Jones and David Henry

Are Drug Companies Living Up to Their Human Rights Responsibilities? The Merck Perspective pp. 1-2

Geralyn S Ritter

Drug Companies Should Be Held More Accountable for Their Human Rights Responsibilities pp. 1-2

The PLoS Medicine Editors

Seventy-Five Trials and Eleven Systematic Reviews a Day: How Will We Ever Keep Up? pp. 1-6

Hilda Bastian, Paul Glasziou and Iain Chalmers

Volume 7, issue 8, 2010

Social Relationships Are Key to Health, and to Health Policy pp. 1-2

The PLoS Medicine Editors

Will Cardiovascular Disease Prevention Widen Health Inequalities? pp. 1-5

Simon Capewell and Hilary Graham

Harnessing Health IT for Improved Cardiovascular Risk Management pp. 1-4

Sue Wells, Robyn Whittaker, Enid Dorey and Chris Bullen

Challenges in Developing Evidence-Based Recommendations Using the GRADE Approach: The Case of Mental, Neurological, and Substance Use Disorders pp. 1-8

Corrado Barbui, Tarun Dua, Mark van Ommeren, M Taghi Yasamy, Alexandra Fleischmann, Nicolas Clark, Graham Thornicroft, Suzanne Hill and Shekhar Saxena

Quantifying the Impoverishing Effects of Purchasing Medicines: A Cross-Country Comparison of the Affordability of Medicines in the Developing World pp. 1-8

Laurens M Niëns, Alexandra Cameron, Ellen Van de Poel, Margaret Ewen, Werner Brouwer and Richard Laing

Assessing Strategy and Equity in the Elimination of Malaria pp. 1-3

Naman K Shah

The Costs and Underappreciated Consequences of Research Misconduct: A Case Study pp. 1-3

Arthur M Michalek, Alan D Hutson, Camille P Wicher and Donald L Trump

Rapid Scaling Up of Insecticide-Treated Bed Net Coverage in Africa and Its Relationship with Development Assistance for Health: A Systematic Synthesis of Supply, Distribution, and Household Survey Data pp. 1-17

Abraham D Flaxman, Nancy Fullman, Mac W Otten, Manoj Menon, Richard E Cibulskis, Marie Ng, Christopher J L Murray and Stephen S Lim

Impact of Community-Based Maternal Health Workers on Coverage of Essential Maternal Health Interventions among Internally Displaced Communities in Eastern Burma: The MOM Project pp. 1-11

Luke C Mullany, Thomas J Lee, Lin Yone, Catherine I Lee, Katherine C Teela, Palae Paw, Eh Kalu Shwe Oo, Cynthia Maung, Heather Kuiper, Nicole F Masenior and Chris Beyrer

Volume 7, issue 7, 2010

Financing Maternal and Child Health—What Are the Limitations in Estimating Donor Flows and Resource Needs? pp. 1-6

Marco Schäferhoff, Christina Schrade and Gavin Yamey

Social Relationships and Mortality Risk: A Meta-analytic Review pp. 1-1

Julianne Holt-Lunstad, Timothy B Smith and J Bradley Layton

A Model for the Roll-Out of Comprehensive Adult Male Circumcision Services in African Low-Income Settings of High HIV Incidence: The ANRS 12126 Bophelo Pele Project pp. 1-13

Pascale Lissouba, Dirk Taljaard, Dino Rech, Sean Doyle, Daniel Shabangu, Cynthia Nhlapo, Josephine Otchere-Darko, Thabo Mashigo, Caitlin Matson, David Lewis, Scott Billy and Bertran Auvert

Improving Implementation: Building Research Capacity in Maternal, Neonatal, and Child Health in Africa pp. 1-3

James Whitworth, Nelson K Sewankambo and Valerie A Snewin

Volume 7, issue 6, 2010

Revised STandards for Reporting Interventions in Clinical Trials of Acupuncture (STRICTA): Extending the CONSORT Statement pp. 1-11

Hugh MacPherson, Douglas G Altman, Richard Hammerschlag, Li Youping, Wu Taixiang, Adrian White, David Moher and on behalf of the STRICTA Revision Group

Evaluating the Quality of Research into a Single Prognostic Biomarker: A Systematic Review and Meta-analysis of 83 Studies of C-Reactive Protein in Stable Coronary Artery Disease pp. 1-11

Harry Hemingway, Peter Philipson, Ruoling Chen, Natalie K Fitzpatrick, Jacqueline Damant, Martin Shipley, Keith R Abrams, Santiago Moreno, Kate S L McAllister, Stephen Palmer, Juan Carlos Kaski, Adam D Timmis and Aroon D Hingorani

The Association of Factor V Leiden and Prothrombin Gene Mutation and Placenta-Mediated Pregnancy Complications: A Systematic Review and Meta-analysis of Prospective Cohort Studies pp. 1-12

Marc A Rodger, Marisol T Betancourt, Peter Clark, Pelle G Lindqvist, Donna Dizon-Townson, Joanne Said, Uri Seligsohn, Marc Carrier, Ophira Salomon and Ian A Greer

Hospital Performance, the Local Economy, and the Local Workforce: Findings from a US National Longitudinal Study pp. 1-12

Jan Blustein, William B Borden and Melissa Valentine

Gestational Age at Delivery and Special Educational Need: Retrospective Cohort Study of 407,503 Schoolchildren pp. 1-10

Daniel F MacKay, Gordon C S Smith, Richard Dobbie and Jill P Pell

Developing ANDI: A Novel Approach to Health Product R&D in Africa pp. 1-6

Solomon Nwaka, Tshinko B Ilunga, Jorge Santos Da Silva, Emiliano Rial Verde, Doan Hackley, Raymond De Vré, Tom Mboya-Okeyo and Robert G Ridley

Volume 7, issue 5, 2010

Journals, Academics, and Pandemics pp. 1-2

The PLoS Medicine Editors

Which New Approaches to Tackling Neglected Tropical Diseases Show Promise? pp. 1-5

Jerry M Spiegel, Shafik Dharamsi, Kishor M Wasan, Annalee Yassi, Burton Singer, Peter J Hotez, Christy Hanson and Donald A P Bundy

Non-Communicable Diseases in Sub-Saharan Africa: The Case for Cohort Studies pp. 1-8

Michelle D Holmes, Shona Dalal, Jimmy Volmink, Clement A Adebamowo, Marina Njelekela, Wafaie W Fawzi, Walter C Willett and Hans-Olov Adami

Can Foreign Policy Make a Difference to Health? pp. 1-3

Sigrun Møgedal and Benedikte Louise Alveberg

Anatomy of the Epidemiological Literature on the 2003 SARS Outbreaks in Hong Kong and Toronto: A Time-Stratified Review pp. 1-11

Weijia Xing, Gilles Hejblum, Gabriel M Leung and Alain-Jacques Valleron

Markers of Dysglycaemia and Risk of Coronary Heart Disease in People without Diabetes: Reykjavik Prospective Study and Systematic Review pp. 1-11

Nadeem Sarwar, Thor Aspelund, Gudny Eiriksdottir, Reeta Gobin, Sreenivasa Rao Kondapally Seshasai, Nita G Forouhi, Gunnar Sigurdsson, John Danesh and Vilmundur Gudnason

The Malawi Developmental Assessment Tool (MDAT): The Creation, Validation, and Reliability of a Tool to Assess Child Development in Rural African Settings pp. 1-14

Melissa Gladstone, Gillian A Lancaster, Eric Umar, Maggie Nyirenda, Edith Kayira, Nynke R van den Broek and Rosalind L Smyth

Volume 7, issue 4, 2010

Does Seasonal Influenza Vaccination Increase the Risk of Illness with the 2009 A/H1N1 Pandemic Virus? pp. 1-3

Cécile Viboud and Lone Simonsen

Mortality Measurement Matters: Improving Data Collection and Estimation Methods for Child and Adult Mortality pp. 1-3

Colin Mathers and Ties Boerma

Health Diplomacy and the Enduring Relevance of Foreign Policy Interests pp. 1-6

Harley Feldbaum and Joshua Michaud

China's Engagement with Global Health Diplomacy: Was SARS a Watershed? pp. 1-6

Lai-Ha Chan, Lucy Chen and Jin Xu

Association between the 2008–09 Seasonal Influenza Vaccine and Pandemic H1N1 Illness during Spring–Summer 2009: Four Observational Studies from Canada pp. 1-15

Danuta M Skowronski, Gaston De Serres, Natasha S Crowcroft, Naveed Z Janjua, Nicole Boulianne, Travis S Hottes, Laura C Rosella, James A Dickinson, Rodica Gilca, Pam Sethi, Najwa Ouhoummane, Donald J Willison, Isabelle Rouleau, Martin Petric, Kevin Fonseca, Steven J Drews, Anuradha Rebbapragada, Hugues Charest, Marie-Ève Hamelin, Guy Boivin, Jennifer L Gardy, Yan Li, Trijntje L Kwindt, David M Patrick, Robert C Brunham and for the Canadian SAVOIR Team

Alternative Strategies to Reduce Maternal Mortality in India: A Cost-Effectiveness Analysis pp. 1-1

Sue J Goldie, Steve Sweet, Natalie Carvalho, Uma Chandra Mouli Natchu and Delphine Hu

Brazil and the Framework Convention on Tobacco Control: Global Health Diplomacy as Soft Power pp. 1-5

Kelley Lee, Luiz Carlos Chagas and Thomas E Novotny

Comparative Effectiveness Research: Challenges for Medical Journals pp. 1-2

Harold C Sox, Mark Helfand, Jeremy Grimshaw, Kay Dickersin, the PLoS Medicine Editors, David Tovey, J André Knottnerus and Peter Tugwell

Measuring Adult Mortality Using Sibling Survival: A New Analytical Method and New Results for 44 Countries, 1974–2006 pp. 1-17

Ziad Obermeyer, Julie Knoll Rajaratnam, Chang H Park, Emmanuela Gakidou, Margaret C Hogan, Alan D Lopez and Christopher J L Murray

What Can We Conclude from Death Registration? Improved Methods for Evaluating Completeness pp. 1-17

Christopher J L Murray, Julie Knoll Rajaratnam, Jacob Marcus, Thomas Laakso and Alan D Lopez

Measuring Under-Five Mortality: Validation of New Low-Cost Methods pp. 1-24

Julie Knoll Rajaratnam, Linda N Tran, Alan D Lopez and Christopher J L Murray

Economic Appraisal of Ontario's Universal Influenza Immunization Program: A Cost-Utility Analysis pp. 1-11

Beate Sander, Jeffrey C Kwong, Chris T Bauch, Andreas Maetzel, Allison McGeer, Janet M Raboud and Murray Krahn

Volume 7, issue 3, 2010

Protecting Vulnerable Road Users from Injury pp. 1-4

Aymery Constant and Emmanuel Lagarde

Can Animal Models of Disease Reliably Inform Human Studies? pp. 1-8

H Bart van der Worp, David W Howells, Emily S Sena, Michelle J Porritt, Sarah Rewell, Victoria O'Collins and Malcolm R Macleod

CONSORT 2010 Statement: Updated Guidelines for Reporting Parallel Group Randomised Trials pp. 1-7

Kenneth F Schulz, Douglas G Altman, David Moher and for the CONSORT Group

Accelerating Policy Decisions to Adopt Haemophilus influenzae Type b Vaccine: A Global, Multivariable Analysis pp. 1-10

Jessica C Shearer, Meghan L Stack, Marcie R Richmond, Allyson P Bear, Rana A Hajjeh and David Bishai

Effects on Coronary Heart Disease of Increasing Polyunsaturated Fat in Place of Saturated Fat: A Systematic Review and Meta-Analysis of Randomized Controlled Trials pp. 1-10

Dariush Mozaffarian, Renata Micha and Sarah Wallace

Drivers of Inequality in Millennium Development Goal Progress: A Statistical Analysis pp. 1-13

David Stuckler, Sanjay Basu and Martin McKee

The Promise of Prevention: The Effects of Four Preventable Risk Factors on National Life Expectancy and Life Expectancy Disparities by Race and County in the United States pp. 1-13

Goodarz Danaei, Eric B Rimm, Shefali Oza, Sandeep C Kulkarni, Christopher J L Murray and Majid Ezzati

Volume 7, issue 2, 2010

Can Broader Diffusion of Value-Based Insurance Design Increase Benefits from US Health Care without Increasing Costs? Evidence from a Computer Simulation Model pp. 1-10

R Scott Braithwaite, Cynthia Omokaro, Amy C Justice, Kimberly Nucifora and Mark S Roberts

Event Rates, Hospital Utilization, and Costs Associated with Major Complications of Diabetes: A Multicountry Comparative Analysis pp. 1-10

Philip M Clarke, Paul Glasziou, Anushka Patel, John Chalmers, Mark Woodward, Stephen B Harrap, Joshua A Salomon and on behalf of the ADVANCE Collaborative Group

Packages of Care for Attention-Deficit Hyperactivity Disorder in Low- and Middle-Income Countries pp. 1-7

Alan J Flisher, Katherine Sorsdahl, Sean Hatherill and Sonia Chehil

Guidance for Developers of Health Research Reporting Guidelines pp. 1-9

David Moher, Kenneth F Schulz, Iveta Simera and Douglas G Altman

Ghostwriting at Elite Academic Medical Centers in the United States pp. 1-4

Jeffrey R Lacasse and Jonathan Leo

A New Policy on Tobacco Papers pp. 1-2

The PLoS Medicine Editors

The Global Research Neglect of Unassisted Smoking Cessation: Causes and Consequences pp. 1-6

Simon Chapman and Ross MacKenzie

Volume 7, issue 1, 2010

The Global Health System: Actors, Norms, and Expectations in Transition pp. 1-4

Nicole A Szlezák, Barry R Bloom, Dean T Jamison, Gerald T Keusch, Catherine M Michaud, Suerie Moon and William C Clark

Meeting the Demand for Results and Accountability: A Call for Action on Health Data from Eight Global Health Agencies pp. 1-4

Margaret Chan, Michel Kazatchkine, Julian Lob-Levyt, Thoraya Obaid, Julian Schweizer, Michel Sidibe, Ann Veneman and Tadataka Yamada

The Global Health System: Strengthening National Health Systems as the Next Step for Global Progress pp. 1-3

Julio Frenk

Relationship between Vehicle Emissions Laws and Incidence of Suicide by Motor Vehicle Exhaust Gas in Australia, 2001–06: An Ecological Analysis pp. 1-9

David M Studdert, Lyle C Gurrin, Uma Jatkar and Jane Pirkis

The Global Health System: Linking Knowledge with Action—Learning from Malaria pp. 1-6

Gerald T Keusch, Wen L Kilama, Suerie Moon, Nicole A Szlezák and Catherine M Michaud

Neonatal Circumcision for HIV Prevention: Cost, Culture, and Behavioral Considerations pp. 1-2

Seth C Kalichman

Science Must Be Responsible to Society, Not to Politics pp. 1-2

The PLoS Medicine Editors

The Global Health System: Lessons for a Stronger Institutional Framework pp. 1-5

Suerie Moon, Nicole A Szlezák, Catherine M Michaud, Dean T Jamison, Gerald T Keusch, William C Clark and Barry R Bloom

Are Patents Impeding Medical Care and Innovation? pp. 1-5

E Richard Gold, Warren Kaplan, James Orbinski, Sarah Harland-Logan and Sevil N-Marandi

“Working the System”—British American Tobacco's Influence on the European Union Treaty and Its Implications for Policy: An Analysis of Internal Tobacco Industry Documents pp. 1-17

Katherine E Smith, Gary Fooks, Jeff Collin, Heide Weishaar, Sema Mandal and Anna B Gilmore

Male Circumcision at Different Ages in Rwanda: A Cost-Effectiveness Study pp. 1-10

Agnes Binagwaho, Elisabetta Pegurri, Jane Muita and Stefano Bertozzi

The Relationship between Anti-merozoite Antibodies and Incidence of Plasmodium falciparum Malaria: A Systematic Review and Meta-analysis pp. 1-20

Freya J I Fowkes, Jack S Richards, Julie A Simpson and James G Beeson