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PLOS Medicine

2004 - 2022

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Volume 15, issue 12, 2018

Better medicine through machine learning: What’s real, and what’s artificial? pp. 1-5 Downloads
Suchi Saria, Atul Butte and Aziz Sheikh
Raltegravir-intensified initial antiretroviral therapy in advanced HIV disease in Africa: A randomised controlled trial pp. 1-20 Downloads
Cissy Kityo, Alexander J Szubert, Abraham Siika, Robert Heyderman, Mutsa Bwakura-Dangarembizi, Abbas Lugemwa, Shalton Mwaringa, Anna Griffiths, Immaculate Nkanya, Sheila Kabahenda, Simon Wachira, Godfrey Musoro, Chatu Rajapakse, Timothy Etyang, James Abach, Moira J Spyer, Priscilla Wavamunno, Linda Nyondo-Mipando, Ennie Chidziva, Kusum Nathoo, Nigel Klein, James Hakim, Diana M Gibb, A Sarah Walker, Sarah L Pett and on behalf of the REALITY trial Team
Supermarket policies on less-healthy food at checkouts: Natural experimental evaluation using interrupted time series analyses of purchases pp. 1-20 Downloads
Katrine T Ejlerskov, Stephen J Sharp, Martine Stead, Ashley J Adamson, Martin White and Jean Adams
A new aging measure captures morbidity and mortality risk across diverse subpopulations from NHANES IV: A cohort study pp. 1-20 Downloads
Zuyun Liu, Pei-Lun Kuo, Steve Horvath, Eileen Crimmins, Luigi Ferrucci and Morgan Levine
Effectiveness and treatment moderators of internet interventions for adult problem drinking: An individual patient data meta-analysis of 19 randomised controlled trials pp. 1-26 Downloads
Heleen Riper, Adriaan Hoogendoorn, Pim Cuijpers, Eirini Karyotaki, Nikolaos Boumparis, Adriana Mira, Gerhard Andersson, Anne H Berman, Nicolas Bertholet, Gallus Bischof, Matthijs Blankers, Brigitte Boon, Leif Boß, Håvar Brendryen, John Cunningham, David Ebert, Anders Hansen, Reid Hester, Zarnie Khadjesari, Jeannet Kramer, Elizabeth Murray, Marloes Postel, Daniela Schulz, Kristina Sinadinovic, Brian Suffoletto, Christopher Sundström, Hein de Vries, Paul Wallace, Reinout W Wiers and Johannes H Smit
Comparative efficacy and acceptability of psychosocial interventions for individuals with cocaine and amphetamine addiction: A systematic review and network meta-analysis pp. 1-24 Downloads
Franco De Crescenzo, Marco Ciabattini, Gian Loreto D’Alò, Riccardo De Giorgi, Cinzia Del Giovane, Carolina Cassar, Luigi Janiri, Nicolas Clark, Michael Joshua Ostacher and Andrea Cipriani
Small for gestational age and risk of childhood mortality: A Swedish population study pp. 1-18 Downloads
Jonas F Ludvigsson, Donghao Lu, Lennart Hammarström, Sven Cnattingius and Fang Fang

Volume 15, issue 11, 2018

Characterising risk of in-hospital mortality following cardiac arrest using machine learning: A retrospective international registry study pp. 1-16 Downloads
Shane Nanayakkara, Sam Fogarty, Michael Tremeer, Kelvin Ross, Brent Richards, Christoph Bergmeir, Sheng Xu, Dion Stub, Karen Smith, Mark Tacey, Danny Liew, David Pilcher and David M Kaye
Healthy volunteers' perceptions of risk in US Phase I clinical trials: A mixed-methods study pp. 1-21 Downloads
Jill A Fisher, Lisa McManus, Marci D Cottingham, Julianne M Kalbaugh, Megan M Wood, Torin Monahan and Rebecca L Walker
Automated detection of moderate and large pneumothorax on frontal chest X-rays using deep convolutional neural networks: A retrospective study pp. 1-15 Downloads
Andrew G Taylor, Clinton Mielke and John Mongan
Machine learning in medicine: Addressing ethical challenges pp. 1-4 Downloads
Effy Vayena, Alessandro Blasimme and I Glenn Cohen
Advancing the beneficial use of machine learning in health care and medicine: Toward a community understanding pp. 1-4 Downloads
Linda Nevin and on behalf of the PLOS Medicine Editors
The use of machine learning to understand the relationship between IgE to specific allergens and asthma pp. 1-3 Downloads
Thomas A E Platts-Mills and Matthew Perzanowski
Machine learning in population health: Opportunities and threats pp. 1-3 Downloads
Abraham D Flaxman and Theo Vos
Predicting the risk of emergency admission with machine learning: Development and validation using linked electronic health records pp. 1-18 Downloads
Fatemeh Rahimian, Gholamreza Salimi-Khorshidi, Amir H Payberah, Jenny Tran, Roberto Ayala Solares, Francesca Raimondi, Milad Nazarzadeh, Dexter Canoy and Kazem Rahimi
Enhancing the prediction of acute kidney injury risk after percutaneous coronary intervention using machine learning techniques: A retrospective cohort study pp. 1-20 Downloads
Chenxi Huang, Karthik Murugiah, Shiwani Mahajan, Shu-Xia Li, Sanket S Dhruva, Julian S Haimovich, Yongfei Wang, Wade L Schulz, Jeffrey M Testani, Francis P Wilson, Carlos I Mena, Frederick A Masoudi, John S Rumsfeld, John A Spertus, Bobak J Mortazavi and Harlan M Krumholz
Machine learning assessment of myocardial ischemia using angiography: Development and retrospective validation pp. 1-19 Downloads
Hyeonyong Hae, Soo-Jin Kang, Won-Jang Kim, So-Yeon Choi, June-Goo Lee, Youngoh Bae, Hyungjoo Cho, Dong Hyun Yang, Joon-Won Kang, Tae-Hwan Lim, Cheol Hyun Lee, Do-Yoon Kang, Pil Hyung Lee, Jung-Min Ahn, Duk-Woo Park, Seung-Whan Lee, Young-Hak Kim, Cheol Whan Lee, Seong-Wook Park and Seung-Jung Park
Development and validation of machine learning models to identify high-risk surgical patients using automatically curated electronic health record data (Pythia): A retrospective, single-site study pp. 1-19 Downloads
Kristin M Corey, Sehj Kashyap, Elizabeth Lorenzi, Sandhya A Lagoo-Deenadayalan, Katherine Heller, Krista Whalen, Suresh Balu, Mitchell T Heflin, Shelley R McDonald, Madhav Swaminathan and Mark Sendak
Relationships between intensity, duration, cumulative dose, and timing of smoking with age at menopause: A pooled analysis of individual data from 17 observational studies pp. 1-19 Downloads
Dongshan Zhu, Hsin-Fang Chung, Nirmala Pandeya, Annette J Dobson, Janet E Cade, Darren C Greenwood, Sybil L Crawford, Nancy E Avis, Ellen B Gold, Ellen S Mitchell, Nancy F Woods, Debra Anderson, Daniel E Brown, Lynnette L Sievert, Eric J Brunner, Diana Kuh, Rebecca Hardy, Kunihiko Hayashi, Jung Su Lee, Hideki Mizunuma, Graham G Giles, Fiona Bruinsma, Therese Tillin, Mette Kildevæld Simonsen, Hans-Olov Adami, Elisabete Weiderpass, Marianne Canonico, Marie-Laure Ancelin, Panayotes Demakakos and Gita D Mishra
Prediction of myopia development among Chinese school-aged children using refraction data from electronic medical records: A retrospective, multicentre machine learning study pp. 1-17 Downloads
Haotian Lin, Erping Long, Xiaohu Ding, Hongxing Diao, Zicong Chen, Runzhong Liu, Jialing Huang, Jingheng Cai, Shuangjuan Xu, Xiayin Zhang, Dongni Wang, Kexin Chen, Tongyong Yu, Dongxuan Wu, Xutu Zhao, Zhenzhen Liu, Xiaohang Wu, Yuzhen Jiang, Xiao Yang, Dongmei Cui, Wenyan Liu, Yingfeng Zheng, Lixia Luo, Haibo Wang, Chi-Chao Chan, Ian G Morgan, Mingguang He and Yizhi Liu
Deep learning for chest radiograph diagnosis: A retrospective comparison of the CheXNeXt algorithm to practicing radiologists pp. 1-17 Downloads
Pranav Rajpurkar, Jeremy Irvin, Robyn L Ball, Kaylie Zhu, Brandon Yang, Hershel Mehta, Tony Duan, Daisy Ding, Aarti Bagul, Curtis P Langlotz, Bhavik N Patel, Kristen W Yeom, Katie Shpanskaya, Francis G Blankenberg, Jayne Seekins, Timothy J Amrhein, David A Mong, Safwan S Halabi, Evan J Zucker, Andrew Y Ng and Matthew P Lungren
Safety, tolerability, and pharmacokinetics of long-acting injectable cabotegravir in low-risk HIV-uninfected individuals: HPTN 077, a phase 2a randomized controlled trial pp. 1-22 Downloads
Raphael J Landovitz, Sue Li, Beatriz Grinsztejn, Halima Dawood, Albert Y Liu, Manya Magnus, Mina C Hosseinipour, Ravindre Panchia, Leslie Cottle, Gordon Chau, Paul Richardson, Mark A Marzinke, Craig W Hendrix, Susan H Eshleman, Yinfeng Zhang, Elizabeth Tolley, Jeremy Sugarman, Ryan Kofron, Adeola Adeyeye, David Burns, Alex R Rinehart, David Margolis, William R Spreen, Myron S Cohen, Marybeth McCauley and Joseph J Eron
Machine learning to identify pairwise interactions between specific IgE antibodies and their association with asthma: A cross-sectional analysis within a population-based birth cohort pp. 1-22 Downloads
Sara Fontanella, Clément Frainay, Clare S Murray, Angela Simpson and Adnan Custovic

Volume 15, issue 10, 2018

Cost-effectiveness of financial incentives and disincentives for improving food purchases and health through the US Supplemental Nutrition Assistance Program (SNAP): A microsimulation study pp. 1-25 Downloads
Dariush Mozaffarian, Junxiu Liu, Stephen Sy, Yue Huang, Colin Rehm, Yujin Lee, Parke Wilde, Shafika Abrahams-Gessel, Thiago de Souza Veiga Jardim, Tom Gaziano and Renata Micha
Prevalence of and reasons for women’s, family members’, and health professionals’ preferences for cesarean section in China: A mixed-methods systematic review pp. 1-25 Downloads
Qian Long, Carol Kingdon, Fan Yang, Michael Dominic Renecle, Shayesteh Jahanfar, Meghan A Bohren and Ana Pilar Betran
In an unhealthy food system, what role should SNAP play? pp. 1-4 Downloads
Hilary Kessler Seligman and Sanjay Basu
Health systems thinking: A new generation of research to improve healthcare quality pp. 1-4 Downloads
Hannah H Leslie, Lisa R Hirschhorn, Tanya Marchant, Svetlana V Doubova, Oye Gureje and Margaret E Kruk
Cesarean section in China, Taiwan, and Hong Kong—A safe choice for women and clinicians? pp. 1-3 Downloads
Mairead Black and Sohinee Bhattacharya
Fatty acid biomarkers of dairy fat consumption and incidence of type 2 diabetes: A pooled analysis of prospective cohort studies pp. 1-18 Downloads
Fumiaki Imamura, Amanda Fretts, Matti Marklund, Andres V Ardisson Korat, Wei-Sin Yang, Maria Lankinen, Waqas Qureshi, Catherine Helmer, Tzu-An Chen, Kerry Wong, Julie K Bassett, Rachel Murphy, Nathan Tintle, Chaoyu Ian Yu, Ingeborg A Brouwer, Kuo-Liong Chien, Alexis C Frazier-Wood, Liana C del Gobbo, Luc Djoussé, Johanna M Geleijnse, Graham G Giles, Janette de Goede, Vilmundur Gudnason, William S Harris, Allison Hodge, Frank Hu, InterAct Consortium, Albert Koulman, Markku Laakso, Lars Lind, Hung-Ju Lin, Barbara McKnight, Kalina Rajaobelina, Ulf Risérus, Jennifer G Robinson, Cécilia Samieri, David S Siscovick, Sabita S Soedamah-Muthu, Nona Sotoodehnia, Qi Sun, Michael Y Tsai, Matti Uusitupa, Lynne E Wagenknecht, Nick J Wareham, Jason HY Wu, Renata Micha, Nita G Forouhi, Rozenn N Lemaitre, Dariush Mozaffarian and Fatty Acids and Outcomes Research Consortium (FORCE)
Retention in HIV care during the 3 years following release from incarceration: A cohort study pp. 1-28 Downloads
Kelsey B Loeliger, Jaimie P Meyer, Mayur M Desai, Maria M Ciarleglio, Colleen Gallagher and Frederick L Altice
Expected changes in obesity after reformulation to reduce added sugars in beverages: A modeling study pp. 1-17 Downloads
Ana Basto-Abreu, Ariela Braverman-Bronstein, Dalia Camacho-García-Formentí, Rodrigo Zepeda-Tello, Barry M Popkin, Juan Rivera-Dommarco, Mauricio Hernández-Ávila and Tonatiuh Barrientos-Gutiérrez
Association between ambient air pollution and daily hospital admissions for ischemic stroke: A nationwide time-series analysis pp. 1-16 Downloads
Yaohua Tian, Hui Liu, Zuolin Zhao, Xiao Xiang, Man Li, Juan Juan, Jing Song, Yaying Cao, Xiaowen Wang, Libo Chen, Chen Wei, Yonghua Hu and Pei Gao
Long-term trends in incidence and risk factors for ischaemic stroke subtypes: Prospective population study of the South London Stroke Register pp. 1-16 Downloads
Hatem A Wafa, Charles D A Wolfe, Anthony Rudd and Yanzhong Wang
Development and validation of a new method for indirect estimation of neonatal, infant, and child mortality trends using summary birth histories pp. 1-23 Downloads
Roy Burstein, Haidong Wang, Robert C Reiner and Simon I Hay

Volume 15, issue 9, 2018

Community delivery of antiretroviral drugs: A non-inferiority cluster-randomized pragmatic trial in Dar es Salaam, Tanzania pp. 1-24 Downloads
Pascal Geldsetzer, Joel M Francis, David Sando, Gerda Asmus, Irene A Lema, Eric Mboggo, Happiness Koda, Sharon Lwezaula, Ramya Ambikapathi, Wafaie Fawzi, Nzovu Ulenga and Till Bärnighausen
Addition of a polygenic risk score, mammographic density, and endogenous hormones to existing breast cancer risk prediction models: A nested case–control study pp. 1-16 Downloads
Xuehong Zhang, Megan Rice, Shelley S Tworoger, Bernard A Rosner, A Heather Eliassen, Rulla M Tamimi, Amit D Joshi, Sara Lindstrom, Jing Qian, Graham A Colditz, Walter C Willett, Peter Kraft and Susan E Hankinson
Nilvadipine in mild to moderate Alzheimer disease: A randomised controlled trial pp. 1-20 Downloads
Brian Lawlor, Ricardo Segurado, Sean Kennelly, Marcel G M Olde Rikkert, Robert Howard, Florence Pasquier, Anne Börjesson-Hanson, Magda Tsolaki, Ugo Lucca, D William Molloy, Robert Coen, Matthias W Riepe, János Kálmán, Rose Anne Kenny, Fiona Cregg, Sarah O'Dwyer, Cathal Walsh, Jessica Adams, Rita Banzi, Laetitia Breuilh, Leslie Daly, Suzanne Hendrix, Paul Aisen, Siobhan Gaynor, Ali Sheikhi, Diana G Taekema, Frans R Verhey, Raffaello Nemni, Flavio Nobili, Massimo Franceschi, Giovanni Frisoni, Orazio Zanetti, Anastasia Konsta, Orologas Anastasios, Styliani Nenopoulou, Fani Tsolaki-Tagaraki, Magdolna Pakaski, Olivier Dereeper, Vincent de la Sayette, Olivier Sénéchal, Isabelle Lavenu, Agnès Devendeville, Gauthier Calais, Fiona Crawford, Michael Mullan and for the NILVAD Study Group
Associations of device-measured physical activity across adolescence with metabolic traits: Prospective cohort study pp. 1-26 Downloads
Joshua A Bell, Mark Hamer, Rebecca C Richmond, Nicholas J Timpson, David Carslake and George Davey Smith
Science Without Publication Paywalls: cOAlition S for the Realisation of Full and Immediate Open Access pp. 1-4 Downloads
Marc Schiltz
Multiple morbidities in pregnancy: Time for research, innovation, and action pp. 1-4 Downloads
James G Beeson, Caroline S E Homer, Christopher Morgan and Clara Menendez

Volume 15, issue 8, 2018

Metabolic syndrome and risk of Parkinson disease: A nationwide cohort study pp. 1-15 Downloads
Ga Eun Nam, Seon Mee Kim, Kyungdo Han, Nan Hee Kim, Hye Soo Chung, Jin Wook Kim, Byoungduck Han, Sung Jung Cho, Ji Hee Yu, Yong Gyu Park and Kyung Mook Choi
Different scientific approaches are needed to generate stronger evidence for population health improvement pp. 1-5 Downloads
Martin White and Jean Adams
Correction: Estimating retention in HIV care accounting for patient transfers: A national laboratory cohort study in South Africa pp. 1-1 Downloads
Matthew P Fox, Jacob Bor, Alana T Brennan, William B MacLeod, Mhairi Maskew, Wendy S Stevens and Sergio Carmona
Family history–based colorectal cancer screening in Australia: A modelling study of the costs, benefits, and harms of different participation scenarios pp. 1-18 Downloads
Mary Dillon, Louisa Flander, Daniel D Buchanan, Finlay A Macrae, Jon D Emery, Ingrid M Winship, Alex Boussioutas, Graham G Giles, John L Hopper, Mark A Jenkins and Driss Ait Ouakrim
Age at puberty and risk of asthma: A Mendelian randomisation study pp. 1-14 Downloads
Cosetta Minelli, Diana A van der Plaat, Bénédicte Leynaert, Raquel Granell, Andre F S Amaral, Miguel Pereira, Osama Mahmoud, James Potts, Nuala A Sheehan, Jack Bowden, John Thompson, Debbie Jarvis, George Davey Smith and John Henderson
Mass azithromycin distribution for hyperendemic trachoma following a cluster-randomized trial: A continuation study of randomly reassigned subclusters (TANA II) pp. 1-17 Downloads
Jeremy D Keenan, Zerihun Tadesse, Sintayehu Gebresillasie, Ayalew Shiferaw, Mulat Zerihun, Paul M Emerson, Kelly Callahan, Sun Y Cotter, Nicole E Stoller, Travis C Porco, Catherine E Oldenburg and Thomas M Lietman

Volume 15, issue 7, 2018

Correction: Complement-activating donor-specific anti-HLA antibodies and solid organ transplant survival: A systematic review and meta-analysis pp. 1-1 Downloads
Antoine Bouquegneau, Charlotte Loheac, Olivier Aubert, Yassine Bouatou, Denis Viglietti, Jean–Philippe Empana, Camilo Ulloa, Mohammad Hassan Murad, Christophe Legendre, Denis Glotz, Annette M Jackson, Adriana Zeevi, Stephan Schaub, Jean–Luc Taupin, Elaine F Reed, John J Friedewald, Dolly B Tyan, Caner Süsal, Ron Shapiro, E Steve Woodle, Luis G Hidalgo, Jacqueline O’Leary, Robert A Montgomery, Jon Kobashigawa, Xavier Jouven, Patricia Jabre, Carmen Lefaucheur and Alexandre Loupy
From advocacy to action: Projecting the health impacts of climate change pp. 1-5 Downloads
Hannah Nissan and Declan Conway
Climate change and health: Moving from theory to practice pp. 1-5 Downloads
Jonathan A Patz and Madeleine C Thomson
Estimating the costs of air pollution to the National Health Service and social care: An assessment and forecast up to 2035 pp. 1-16 Downloads
Laura Pimpin, Lise Retat, Daniela Fecht, Laure de Preux, Franco Sassi, John Gulliver, Annalisa Belloni, Brian Ferguson, Emily Corbould, Abbygail Jaccard and Laura Webber
Life cycle environmental emissions and health damages from the Canadian healthcare system: An economic-environmental-epidemiological analysis pp. 1-16 Downloads
Matthew J Eckelman, Jodi D Sherman and Andrea J MacNeill
Improving rational use of ACTs through diagnosis-dependent subsidies: Evidence from a cluster-randomized controlled trial in western Kenya pp. 1-24 Downloads
Wendy Prudhomme O’Meara, Diana Menya, Jeremiah Laktabai, Alyssa Platt, Indrani Saran, Elisa Maffioli, Joseph Kipkoech, Manoj Mohanan and Elizabeth L Turner
Carbon pricing, co-pollutants, and climate policy: Evidence from California pp. 1-3 Downloads
James K Boyce and Michael Ash
Sexual transmission of Zika virus and other flaviviruses: A living systematic review pp. 1-25 Downloads
Michel Jacques Counotte, Caron Rahn Kim, Jingying Wang, Kyle Bernstein, Carolyn D Deal, Nathalie Jeanne Nicole Broutet and Nicola Low
Heat-related mortality trends under recent climate warming in Spain: A 36-year observational study pp. 1-17 Downloads
Hicham Achebak, Daniel Devolder and Joan Ballester
Mortality attributable to hot and cold ambient temperatures in India: a nationally representative case-crossover study pp. 1-17 Downloads
Sze Hang Fu, Antonio Gasparrini, Peter S Rodriguez and Prabhat Jha
Quantifying excess deaths related to heatwaves under climate change scenarios: A multicountry time series modelling study pp. 1-17 Downloads
Yuming Guo, Antonio Gasparrini, Shanshan Li, Francesco Sera, Ana Maria Vicedo-Cabrera, Micheline de Sousa Zanotti Stagliorio Coelho, Paulo Hilario Nascimento Saldiva, Eric Lavigne, Benjawan Tawatsupa, Kornwipa Punnasiri, Ala Overcenco, Patricia Matus Correa, Nicolas Valdes Ortega, Haidong Kan, Samuel Osorio, Jouni J K Jaakkola, Niilo R I Ryti, Patrick G Goodman, Ariana Zeka, Paola Michelozzi, Matteo Scortichini, Masahiro Hashizume, Yasushi Honda, Xerxes Seposo, Ho Kim, Aurelio Tobias, Carmen Íñiguez, Bertil Forsberg, Daniel Oudin Åström, Yue Leon Guo, Bing-Yu Chen, Antonella Zanobetti, Joel Schwartz, Tran Ngoc Dang, Dung Do Van, Michelle L Bell, Ben Armstrong, Kristie L Ebi and Shilu Tong
Climate change and women's health: Impacts and policy directions pp. 1-10 Downloads
Cecilia Sorensen, Virginia Murray, Jay Lemery and John Balbus
Air-quality-related health impacts from climate change and from adaptation of cooling demand for buildings in the eastern United States: An interdisciplinary modeling study pp. 1-27 Downloads
David W Abel, Tracey Holloway, Monica Harkey, Paul Meier, Doug Ahl, Vijay S Limaye and Jonathan A Patz
Chile’s 2014 sugar-sweetened beverage tax and changes in prices and purchases of sugar-sweetened beverages: An observational study in an urban environment pp. 1-19 Downloads
Juan Carlos Caro, Camila Corvalán, Marcela Reyes, Andres Silva, Barry Popkin and Lindsey Smith Taillie
Neurodevelopmental disorders in children aged 2–9 years: Population-based burden estimates across five regions in India pp. 1-19 Downloads
Narendra K Arora, M K C Nair, Sheffali Gulati, Vaishali Deshmukh, Archisman Mohapatra, Devendra Mishra, Vikram Patel, Ravindra M Pandey, Bhagabati C Das, Gauri Divan, G V S Murthy, Thakur D Sharma, Savita Sapra, Satinder Aneja, Monica Juneja, Sunanda K Reddy, Praveen Suman, Sharmila B Mukherjee, Rajib Dasgupta, Poma Tudu, Manoja K Das, Vinod K Bhutani, Maureen S Durkin, Jennifer Pinto-Martin, Donald H Silberberg, Rajesh Sagar, Faruqueuddin Ahmed, Nandita Babu, Sandeep Bavdekar, Vijay Chandra, Zia Chaudhuri, Tanuj Dada, Rashna Dass, M Gourie-Devi, S Remadevi, Jagdish C Gupta, Kumud K Handa, Veena Kalra, Sunil Karande, Ramesh Konanki, Madhuri Kulkarni, Rashmi Kumar, Arti Maria, Muneer A Masoodi, Manju Mehta, Santosh Kumar Mohanty, Harikumaran Nair, Poonam Natarajan, A K Niswade, Atul Prasad, Sanjay K Rai, Paul S S Russell, Rohit Saxena, Shobha Sharma, Arun K Singh, Gautam B Singh, Leena Sumaraj, Saradha Suresh, Alok Thakar, Sujatha Parthasarathy, Bhadresh Vyas, Ansuman Panigrahi, Munish K Saroch, Rajan Shukla, K V Raghava Rao, Maria P Silveira, Samiksha Singh and Vivek Vajaratkar
Carbon trading, co-pollutants, and environmental equity: Evidence from California’s cap-and-trade program (2011–2015) pp. 1-20 Downloads
Lara Cushing, Dan Blaustein-Rejto, Madeline Wander, Manuel Pastor, James Sadd, Allen Zhu and Rachel Morello-Frosch
Reduced cognitive function during a heat wave among residents of non-air-conditioned buildings: An observational study of young adults in the summer of 2016 pp. 1-20 Downloads
Jose Guillermo Cedeño Laurent, Augusta Williams, Youssef Oulhote, Antonella Zanobetti, Joseph G Allen and John D Spengler
Evaluating the 2014 sugar-sweetened beverage tax in Chile: An observational study in urban areas pp. 1-22 Downloads
Ryota Nakamura, Andrew J Mirelman, Cristóbal Cuadrado, Nicolas Silva-Illanes, Jocelyn Dunstan and Marc Suhrcke
Adherence interventions and outcomes of tuberculosis treatment: A systematic review and meta-analysis of trials and observational studies pp. 1-44 Downloads
Narges Alipanah, Leah Jarlsberg, Cecily Miller, Nguyen Nhat Linh, Dennis Falzon, Ernesto Jaramillo and Payam Nahid

Volume 15, issue 6, 2018

Academic response to improving value and reducing waste: A comprehensive framework for INcreasing QUality In patient-oriented academic clinical REsearch (INQUIRE) pp. 1-19 Downloads
Belinda von Niederhäusern, Gordon H Guyatt, Matthias Briel and Christiane Pauli-Magnus
Efficacy of melatonin with behavioural sleep-wake scheduling for delayed sleep-wake phase disorder: A double-blind, randomised clinical trial pp. 1-24 Downloads
Tracey L Sletten, Michelle Magee, Jade M Murray, Christopher J Gordon, Nicole Lovato, David J Kennaway, Stella M Gwini, Delwyn J Bartlett, Steven W Lockley, Leon C Lack, Ronald R Grunstein, Shantha M W Rajaratnam and for the Delayed Sleep on Melatonin (DelSoM) Study Group
Comparing post-acute rehabilitation use, length of stay, and outcomes experienced by Medicare fee-for-service and Medicare Advantage beneficiaries with hip fracture in the United States: A secondary analysis of administrative data pp. 1-14 Downloads
Amit Kumar, Momotazur Rahman, Amal N Trivedi, Linda Resnik, Pedro Gozalo and Vincent Mor
Estimating retention in HIV care accounting for patient transfers: A national laboratory cohort study in South Africa pp. 1-21 Downloads
Matthew P Fox, Jacob Bor, Alana T Brennan, William B MacLeod, Mhairi Maskew, Wendy S Stevens and Sergio Carmona
Fixed-dose combination antihypertensive medications, adherence, and clinical outcomes: A population-based retrospective cohort study pp. 1-18 Downloads
Amol A Verma, Wayne Khuu, Mina Tadrous, Tara Gomes and Muhammad M Mamdani
Trade challenges at the World Trade Organization to national noncommunicable disease prevention policies: A thematic document analysis of trade and health policy space pp. 1-18 Downloads
Pepita Barlow, Ronald Labonte, Martin McKee and David Stuckler
Correction: Distributional change of women’s adult height in low- and middle-income countries over the past half century: An observational study using cross-sectional survey data pp. 1-1 Downloads
Jewel Gausman, Iván Mejía-Guevara, S V Subramanian and Fahad Razak
Correction: Prevalence of sexually transmitted infections and bacterial vaginosis among women in sub-Saharan Africa: An individual participant data meta-analysis of 18 HIV prevention studies pp. 1-1 Downloads
Elizabeth A Torrone, Charles S Morrison, Pai-Lien Chen, Cynthia Kwok, Suzanna C Francis, Richard J Hayes, Katharine J Looker, Sheena McCormack, Nuala McGrath, Janneke H H M van de Wijgert, Deborah Watson-Jones, Nicola Low, Sami L Gottlieb and on behalf of the STIMA Working Group

Volume 15, issue 5, 2018

Correction: Multimorbidity in patients with heart failure from 11 Asian regions: A prospective cohort study using the ASIAN-HF registry pp. 1-1 Downloads
Jasper Tromp, Wan Ting Tay, Wouter Ouwerkerk, Tiew-Hwa Katherine Teng, Jonathan Yap, Michael R MacDonald, Kirsten Leineweber, John J V McMurray, Michael R Zile, Inder S Anand, A Mark Richards, Carolyn S P Lam and Authors Asian-Hf
Complement-activating donor-specific anti-HLA antibodies and solid organ transplant survival: A systematic review and meta-analysis pp. 1-25 Downloads
Antoine Bouquegneau, Charlotte Loheac, Olivier Aubert, Yassine Bouatou, Denis Viglietti, Jean–Philippe Empana, Camilo Ulloa, Mohammad Hassan Murad, Christophe Legendre, Denis Glotz, Annette M Jackson, Adriana Zeevi, Stephan Schaub, Jean–Luc Taupin, Elaine F Reed, John J Friedewald, Dolly B Tyan, Caner Süsal, Ron Shapiro, E Steve Woodle, Luis G Hidalgo, Jacqueline O’Leary, Robert A Montgomery, Jon Kobashigawa, Xavier Jouven, Patricia Jabre, Carmen Lefaucheur and Alexandre Loupy
The next forum for unraveling FDA off-label marketing rules: State and federal legislatures pp. 1-3 Downloads
Michael S Sinha and Aaron S Kesselheim
All science should inform policy and regulation pp. 1-3 Downloads
John P A Ioannidis
Ibuprofen versus pivmecillinam for uncomplicated urinary tract infection in women—A double-blind, randomized non-inferiority trial pp. 1-21 Downloads
Ingvild Vik, Marianne Bollestad, Nils Grude, Anders Bærheim, Eivind Damsgaard, Thomas Neumark, Lars Bjerrum, Gloria Cordoba, Inge Christoffer Olsen and Morten Lindbæk
Injury and death during the ISIS occupation of Mosul and its liberation: Results from a 40-cluster household survey pp. 1-20 Downloads
Riyadh Lafta, Maha A Al-Nuaimi and Gilbert Burnham
Child morbidity and mortality associated with alternative policy responses to the economic crisis in Brazil: A nationwide microsimulation study pp. 1-20 Downloads
Davide Rasella, Sanjay Basu, Thomas Hone, Romulo Paes-Sousa, Carlos Octávio Ocké-Reis and Christopher Millett
Future cost-effectiveness and equity of the NHS Health Check cardiovascular disease prevention programme: Microsimulation modelling using data from Liverpool, UK pp. 1-20 Downloads
Chris Kypridemos, Brendan Collins, Philip McHale, Helen Bromley, Paula Parvulescu, Simon Capewell and Martin O’Flaherty
Distributional change of women’s adult height in low- and middle-income countries over the past half century: An observational study using cross-sectional survey data pp. 1-27 Downloads
Jewel Gausman, Ivan Meija Guevara, S V Subramanian and Fahad Razak
Clinical, socioeconomic, and behavioural factors at age 50 years and risk of cardiometabolic multimorbidity and mortality: A cohort study pp. 1-16 Downloads
Archana Singh-Manoux, Aurore Fayosse, Séverine Sabia, Adam Tabak, Martin Shipley, Aline Dugravot and Mika Kivimäki
Health insurance coverage with or without a nurse-led task shifting strategy for hypertension control: A pragmatic cluster randomized trial in Ghana pp. 1-17 Downloads
Gbenga Ogedegbe, Jacob Plange-Rhule, Joyce Gyamfi, William Chaplin, Michael Ntim, Kingsley Apusiga, Juliet Iwelunmor, Kwasi Yeboah Awudzi, Kofi Nana Quakyi, Jazmin Mogaverro, Kiran Khurshid, Bamidele Tayo and Richard Cooper
Association of vitamin D with risk of type 2 diabetes: A Mendelian randomisation study in European and Chinese adults pp. 1-17 Downloads
Ling Lu, Derrick A Bennett, Iona Y Millwood, Sarah Parish, Mark I McCarthy, Anubha Mahajan, Xu Lin, Fiona Bragg, Yu Guo, Michael V Holmes, Shoaib Afzal, Børge G Nordestgaard, Zheng Bian, Michael Hill, Robin G Walters, Liming Li, Zhengming Chen and Robert Clarke

Volume 15, issue 4, 2018

From surviving to thriving: What evidence is needed to move early child-development interventions to scale? pp. 1-3 Downloads
Mark Tomlinson
Preprints in medical research: Progress and principles pp. 1-3 Downloads
Larry Peiperl and on behalf of the PLOS Medicine Editors
Estimating the health and economic effects of the proposed US Food and Drug Administration voluntary sodium reformulation: Microsimulation cost-effectiveness analysis pp. 1-18 Downloads
Jonathan Pearson-Stuttard, Chris Kypridemos, Brendan Collins, Dariush Mozaffarian, Yue Huang, Piotr Bandosz, Simon Capewell, Laurie Whitsel, Parke Wilde, Martin O’Flaherty and Renata Micha
Preprints: An underutilized mechanism to accelerate outbreak science pp. 1-5 Downloads
Michael A Johansson, Nicholas G Reich, Lauren Ancel Meyers and Marc Lipsitch
Impacts 2 years after a scalable early childhood development intervention to increase psychosocial stimulation in the home: A follow-up of a cluster randomised controlled trial in Colombia pp. 1-19 Downloads
Alison Andrew, Orazio Attanasio, Emla Fitzsimons, Sally Grantham-McGregor, Costas Meghir and Marta Rubio-Codina
Breastfeeding during infancy and neurocognitive function in adolescence: 16-year follow-up of the PROBIT cluster-randomized trial pp. 1-16 Downloads
Seungmi Yang, Richard M Martin, Emily Oken, Mikhail Hameza, Glen Doniger, Shimon Amit, Rita Patel, Jennifer Thompson, Sheryl L Rifas-Shiman, Konstantin Vilchuck, Natalia Bogdanovich and Michael S Kramer

Volume 15, issue 3, 2018

Surveillance of antimicrobial consumption in animal production sectors of low- and middle-income countries: Optimizing use and addressing antimicrobial resistance pp. 1-9 Downloads
Daniel Schar, Angkana Sommanustweechai, Ramanan Laxminarayan and Viroj Tangcharoensathien
What is the value of multidisciplinary care for chronic kidney disease? pp. 1-3 Downloads
Richard J Fluck and Maarten W Taal
Cardiovascular disease and multimorbidity: A call for interdisciplinary research and personalized cardiovascular care pp. 1-3 Downloads
Kazem Rahimi, Carolyn S P Lam and Steven Steinhubl
Mortality, ethnicity, and country of birth on a national scale, 2001–2013: A retrospective cohort (Scottish Health and Ethnicity Linkage Study) pp. 1-18 Downloads
Raj S Bhopal, Laurence Gruer, Genevieve Cezard, Anne Douglas, Markus F C Steiner, Andrew Millard, Duncan Buchanan, S Vittal Katikireddi and Aziz Sheikh
Delays in completion and results reporting of clinical trials under the Paediatric Regulation in the European Union: A cohort study pp. 1-15 Downloads
Thomas J Hwang, Paolo A Tomasi and Florence T Bourgeois
The epidemiology of adolescents living with perinatally acquired HIV: A cross-region global cohort analysis pp. 1-21 Downloads
The Collaborative Initiative for Paediatric HIV Education and Research (CIPHER) Global Cohort Collaboration, Amy L Slogrove, Michael Schomaker, Mary-Ann Davies, Paige Williams, Suna Balkan, Jihane Ben-Farhat, Nancy Calles, Kulkanya Chokephaibulkit, Charlotte Duff, Tanoh François Eboua, Adeodata Kekitiinwa-Rukyalekere, Nicola Maxwell, Jorge Pinto, George Seage, Chloe A Teasdale, Sebastian Wanless, Josiane Warszawski, Kara Wools-Kaloustian, Marcel Yotebieng, Venessa Timmerman, Intira J Collins, Ruth Goodall, Colette Smith, Kunjal Patel, Mary Paul, Diana Gibb, Rachel Vreeman, Elaine J Abrams, Rohan Hazra, Russell Van Dyke, Linda-Gail Bekker, Lynne Mofenson, Marissa Vicari, Shaffiq Essajee, Martina Penazzato, Gabriel Anabwani, Edith Q. Mohapi, Peter N. Kazembe, Makhosazana Hlatshwayo, Mwita Lumumba, Tessa Goetghebuer, Claire Thorne, Luisa Galli, Annemarie van Rossum, Carlo Giaquinto, Magdalena Marczynska, Laura Marques, Filipa Prata, Luminita Ene, Liubov Okhonskaia, Pablo Rojo, Claudia Fortuny, Lars Naver, Christoph Rudin, Sophie Le Coeur, Alla Volokha, Vanessa Rouzier, Regina Succi, Annette Sohn, Azar Kariminia, Andrew Edmonds, Patricia Lelo, Samuel Ayaya, Patricia Ongwen, Laura F Jefferys, Sam Phiri, Mwangelwa Mubiana-Mbewe, Shobna Sawry, Lorna Renner, Mariam Sylla, Mark J Abzug, Myron Levin, James Oleske, Miriam Chernoff, Shirley Traite, Murli Purswani, Ellen G Chadwick, Ali Judd and Valériane Leroy
Patterns and temporal trends of comorbidity among adult patients with incident cardiovascular disease in the UK between 2000 and 2014: A population-based cohort study pp. 1-23 Downloads
Jenny Tran, Robyn Norton, Nathalie Conrad, Fatemeh Rahimian, Dexter Canoy, Milad Nazarzadeh and Kazem Rahimi
Cost-effectiveness of multidisciplinary care in mild to moderate chronic kidney disease in the United States: A modeling study pp. 1-29 Downloads
Eugene Lin, Glenn M Chertow, Brandon Yan, Elizabeth Malcolm and Jeremy D Goldhaber-Fiebert

Volume 15, issue 2, 2018

Susceptibility of Neisseria gonorrhoeae to azithromycin and ceftriaxone in China: A retrospective study of national surveillance data from 2013 to 2016 pp. 1-14 Downloads
Yue-Ping Yin, Yan Han, Xiu-Qin Dai, He-Ping Zheng, Shao-Chun Chen, Bang-Yong Zhu, Gang Yong, Na Zhong, Li-Hua Hu, Wen-Ling Cao, Zhong-Jie Zheng, Feng Wang, Qi Zhi, Xiao-Yu Zhu and Xiang-Sheng Chen
The 2014–2015 Ebola virus disease outbreak and primary healthcare delivery in Liberia: Time-series analyses for 2010–2016 pp. 1-26 Downloads
Bradley H Wagenaar, Orvalho Augusto, Jason Beste, Stephen J Toomay, Eugene Wickett, Nelson Dunbar, Luke Bawo and Chea Sanford Wesseh
The potential impact of case-area targeted interventions in response to cholera outbreaks: A modeling study pp. 1-27 Downloads
Flavio Finger, Enrico Bertuzzo, Francisco J Luquero, Nathan Naibei, Brahima Touré, Maya Allan, Klaudia Porten, Justin Lessler, Andrea Rinaldo and Andrew S Azman
Impact of person-centred care training and person-centred activities on quality of life, agitation, and antipsychotic use in people with dementia living in nursing homes: A cluster-randomised controlled trial pp. 1-18 Downloads
Clive Ballard, Anne Corbett, Martin Orrell, Gareth Williams, Esme Moniz-Cook, Renee Romeo, Bob Woods, Lucy Garrod, Ingelin Testad, Barbara Woodward-Carlton, Jennifer Wenborn, Martin Knapp and Jane Fossey
Preventing cholera outbreaks through early targeted interventions pp. 1-4 Downloads
Lorenz von Seidlein and Jacqueline L Deen
Setbacks in Alzheimer research demand new strategies, not surrender pp. 1-4 Downloads
Björn Jobke, Thomas McBride, Linda Nevin, Larry Peiperl, Amy Ross, Clare Stone, Richard Turner and as the PLOS Medicine Editors
Risk and surrogate benefit for pediatric Phase I trials in oncology: A systematic review with meta-analysis pp. 1-15 Downloads
Marcin Waligora, Malgorzata M Bala, Magdalena Koperny, Mateusz T Wasylewski, Karolina Strzebonska, Rafał R Jaeschke, Agnieszka Wozniak, Jan Piasecki, Agnieszka Sliwka, Jerzy W Mitus, Maciej Polak, Dominika Nowis, Dean Fergusson and Jonathan Kimmelman
Population impact of lung cancer screening in the United States: Projections from a microsimulation model pp. 1-15 Downloads
Steven D Criss, Deirdre F Sheehan, Lauren Palazzo and Chung Yin Kong
Correction: Association between the 2012 Health and Social Care Act and specialist visits and hospitalisations in England: A controlled interrupted time series analysis pp. 1-1 Downloads
The PLOS Medicine Staff
Diet during pregnancy and infancy and risk of allergic or autoimmune disease: A systematic review and meta-analysis pp. 1-25 Downloads
Vanessa Garcia-Larsen, Despo Ierodiakonou, Katharine Jarrold, Sergio Cunha, Jennifer Chivinge, Zoe Robinson, Natalie Geoghegan, Alisha Ruparelia, Pooja Devani, Marialena Trivella, Jo Leonardi-Bee and Robert J Boyle

Volume 15, issue 1, 2018

What about drinking is associated with shorter life in poorer people? pp. 1-3 Downloads
Jürgen Rehm and Charlotte Probst
From macro- to microfactors in health: Social science approaches in research on sexually transmitted infections pp. 1-3 Downloads
Ruth Kutalek, Elena Jirovsky and Igor Grabovac
The WHO 2016 verbal autopsy instrument: An international standard suitable for automated analysis by InterVA, InSilicoVA, and Tariff 2.0 pp. 1-9 Downloads
Erin K Nichols, Peter Byass, Daniel Chandramohan, Samuel J Clark, Abraham D Flaxman, Robert Jakob, Jordana Leitao, Nicolas Maire, Chalapati Rao, Ian Riley, Philip W Setel and on behalf of the WHO Verbal Autopsy Working Group
The cost-effectiveness of alternative vaccination strategies for polyvalent meningococcal vaccines in Burkina Faso: A transmission dynamic modeling study pp. 1-18 Downloads
Reza Yaesoubi, Caroline Trotter, Caroline Colijn, Maziar Yaesoubi, Anaïs Colombini, Stephen Resch, Paul A Kristiansen, F Marc LaForce and Ted Cohen
Progression of the first stage of spontaneous labour: A prospective cohort study in two sub-Saharan African countries pp. 1-30 Downloads
Olufemi T Oladapo, Joao Paulo Souza, Bukola Fawole, Kidza Mugerwa, Gleici Perdoná, Domingos Alves, Hayala Souza, Rodrigo Reis, Livia Oliveira-Ciabati, Alexandre Maiorano, Adesina Akintan, Francis E Alu, Lawal Oyeneyin, Amos Adebayo, Josaphat Byamugisha, Miriam Nakalembe, Hadiza A Idris, Ola Okike, Fernando Althabe, Vanora Hundley, France Donnay, Robert Pattinson, Harshadkumar C Sanghvi, Jen E Jardine, Özge Tunçalp, Joshua P Vogel, Mary Ellen Stanton, Meghan Bohren, Jun Zhang, Tina Lavender, Jerker Liljestrand, Petra ten Hoope-Bender, Matthews Mathai, Rajiv Bahl and A Metin Gülmezoglu
Long-term risks and benefits associated with cesarean delivery for mother, baby, and subsequent pregnancies: Systematic review and meta-analysis pp. 1-22 Downloads
Oonagh E Keag, Jane E Norman and Sarah J Stock
Estimated mortality on HIV treatment among active patients and patients lost to follow-up in 4 provinces of Zambia: Findings from a multistage sampling-based survey pp. 1-19 Downloads
Charles B Holmes, Izukanji Sikazwe, Kombatende Sikombe, Ingrid Eshun-Wilson, Nancy Czaicki, Laura K Beres, Njekwa Mukamba, Sandra Simbeza, Carolyn Bolton Moore, Cardinal Hantuba, Peter Mwaba, Caroline Phiri, Nancy Padian, David V Glidden and Elvin Geng
Traumatic brain injury and the risk of dementia diagnosis: A nationwide cohort study pp. 1-13 Downloads
Anna Nordström and Peter Nordström
Life course socioeconomic position, alcohol drinking patterns in midlife, and cardiovascular mortality: Analysis of Norwegian population-based health surveys pp. 1-20 Downloads
Eirik Degerud, Inger Ariansen, Eivind Ystrom, Sidsel Graff-Iversen, Gudrun Høiseth, Jørg Mørland, George Davey Smith and Øyvind Næss
Safety and pharmacokinetics of the Fc-modified HIV-1 human monoclonal antibody VRC01LS: A Phase 1 open-label clinical trial in healthy adults pp. 1-20 Downloads
Martin R Gaudinski, Emily E Coates, Katherine V Houser, Grace L Chen, Galina Yamshchikov, Jamie G Saunders, LaSonji A Holman, Ingelise Gordon, Sarah Plummer, Cynthia S Hendel, Michelle Conan-Cibotti, Margarita Gomez Lorenzo, Sandra Sitar, Kevin Carlton, Carolyn Laurencot, Robert T Bailer, Sandeep Narpala, Adrian B McDermott, Aryan M Namboodiri, Janardan P Pandey, Richard M Schwartz, Zonghui Hu, Richard A Koup, Edmund Capparelli, Barney S Graham, John R Mascola, Julie E Ledgerwood and the VRC 606 Study Team
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