PLOS Medicine

2004 - 2022

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Volume 12, issue 12, 2015

Inequalities in Alcohol-Related Mortality in 17 European Countries: A Retrospective Analysis of Mortality Registers pp. 1-31

Johan P Mackenbach, Ivana Kulhánová, Matthias Bopp, Carme Borrell, Patrick Deboosere, Katalin Kovács, Caspar W N Looman, Mall Leinsalu, Pia Mäkelä, Pekka Martikainen, Gwenn Menvielle, Maica Rodríguez-Sanz, Jitka Rychtaříková and Rianne de Gelder

Acute Cardiovascular Events after Herpes Zoster: A Self-Controlled Case Series Analysis in Vaccinated and Unvaccinated Older Residents of the United States pp. 1-15

Caroline Minassian, Sara L Thomas, Liam Smeeth, Ian Douglas, Ruth Brauer and Sinéad M Langan

Risks and Benefits of Nalmefene in the Treatment of Adult Alcohol Dependence: A Systematic Literature Review and Meta-Analysis of Published and Unpublished Double-Blind Randomized Controlled Trials pp. 1-17

Clément Palpacuer, Bruno Laviolle, Rémy Boussageon, Jean Michel Reymann, Eric Bellissant and Florian Naudet

Self-Administered Outpatient Antimicrobial Infusion by Uninsured Patients Discharged from a Safety-Net Hospital: A Propensity-Score-Balanced Retrospective Cohort Study pp. 1-18

Kavita P Bhavan, L Steven Brown and Robert W Haley

Moving Beyond “Food Deserts”: Reorienting United States Policies to Reduce Disparities in Diet Quality pp. 1-9

Jason P Block and S V Subramanian

Diversity in Clinical and Biomedical Research: A Promise Yet to Be Fulfilled pp. 1-9

Sam S Oh, Joshua Galanter, Neeta Thakur, Maria Pino-Yanes, Nicolas E Barcelo, Marquitta J White, Danielle M de Bruin, Ruth M Greenblatt, Kirsten Bibbins-Domingo, Alan H B Wu, Luisa N Borrell, Chris Gunter, Neil R Powe and Esteban G Burchard

Volume 12, issue 11, 2015

The HIV Treatment Gap: Estimates of the Financial Resources Needed versus Available for Scale-Up of Antiretroviral Therapy in 97 Countries from 2015 to 2020 pp. 1-43

Arin Dutta, Catherine Barker and Ashley Kallarakal

Care that Matters: Quality Measurement and Health Care pp. 1-10

Barry G Saver, Stephen A Martin, Ronald N Adler, Lucy M Candib, Konstantinos E Deligiannidis, Jeremy Golding, Daniel J Mullin, Michele Roberts and Stefan Topolski

Venous Thrombosis Risk after Cast Immobilization of the Lower Extremity: Derivation and Validation of a Clinical Prediction Score, L-TRiP(cast), in Three Population-Based Case–Control Studies pp. 1-20

Banne Nemeth, Raymond A van Adrichem, Astrid van Hylckama Vlieg, Paolo Bucciarelli, Ida Martinelli, Trevor Baglin, Frits R Rosendaal, Saskia le Cessie and Suzanne C Cannegieter

The First Use of the Global Oral Cholera Vaccine Emergency Stockpile: Lessons from South Sudan pp. 1-8

Abdinasir Abubakar, Andrew S Azman, John Rumunu, Iza Ciglenecki, Trina Helderman, Haley West, Justin Lessler, David A Sack, Stephen Martin, William Perea, Dominique Legros and Francisco J Luquero

From Checklists to Tools: Lowering the Barrier to Better Research Reporting pp. 1-4

The PLOS Medicine Editors

Volume 12, issue 10, 2015

Continuity in Drinking Water Supply pp. 1-2

Clarissa Brocklehurst and Tom Slaymaker

Transparency in Reporting Observational Studies: Reflections after a Year pp. 1-4

The PLOS Medicine Editors

Using Qualitative Evidence in Decision Making for Health and Social Interventions: An Approach to Assess Confidence in Findings from Qualitative Evidence Syntheses (GRADE-CERQual) pp. 1-18

Simon Lewin, Claire Glenton, Heather Munthe-Kaas, Benedicte Carlsen, Christopher J Colvin, Metin Gülmezoglu, Jane Noyes, Andrew Booth, Ruth Garside and Arash Rashidian

Monitoring Mortality in Forced Migrants—Can Bayesian Methods Help Us to Do Better with the (Little) Data We Have? pp. 1-7

Peter Heudtlass, Niko Speybroeck and Debarati Guha-Sapir

Effect of Health Risk Assessment and Counselling on Health Behaviour and Survival in Older People: A Pragmatic Randomised Trial pp. 1-21

Andreas E Stuck, André Moser, Ueli Morf, Urban Wirz, Joseph Wyser, Gerhard Gillmann, Stephan Born, Marcel Zwahlen, Steve Iliffe, Danielle Harari, Cameron Swift, John C Beck and Matthias Egger

Individual Participant Data (IPD) Meta-analyses of Diagnostic and Prognostic Modeling Studies: Guidance on Their Use pp. 1-12

Thomas P A Debray, Richard D Riley, Maroeska M Rovers, Johannes B Reitsma, Karel G M Moons and Cochrane IPD Meta-analysis Methods Group

The REporting of studies Conducted using Observational Routinely-collected health Data (RECORD) Statement pp. 1-22

Eric I Benchimol, Liam Smeeth, Astrid Guttmann, Katie Harron, David Moher, Irene Petersen, Henrik T Sørensen, Erik von Elm, Sinéad M Langan and Working Committee Record

Volume 12, issue 9, 2015

Uptake, Accuracy, Safety, and Linkage into Care over Two Years of Promoting Annual Self-Testing for HIV in Blantyre, Malawi: A Community-Based Prospective Study pp. 1-21

Augustine T Choko, Peter MacPherson, Emily L Webb, Barbara A Willey, Helena Feasy, Rodrick Sambakunsi, Aaron Mdolo, Simon D Makombe, Nicola Desmond, Richard Hayes, Hendramoorthy Maheswaran and Elizabeth L Corbett

The Impact of Company-Level ART Provision to a Mining Workforce in South Africa: A Cost–Benefit Analysis pp. 1-26

Gesine Meyer-Rath, Jan Pienaar, Brian Brink, Andrew van Zyl, Debbie Muirhead, Alison Grant, Gavin Churchyard, Charlotte Watts and Peter Vickerman

Value of Information: A Tool to Improve Research Prioritization and Reduce Waste pp. 1-5

Cosetta Minelli and Gianluca Baio

Four Proposals to Help Improve the Medical Research Literature pp. 1-7

David Moher and Douglas G Altman

Equity and Noncommunicable Disease Reduction under the Sustainable Development Goals pp. 1-7

Harald Schmidt and Anne Barnhill

Volume 12, issue 8, 2015

The Cost-Effectiveness of Low-Cost Essential Antihypertensive Medicines for Hypertension Control in China: A Modelling Study pp. 1-19

Dongfeng Gu, Jiang He, Pamela G Coxson, Petra W Rasmussen, Chen Huang, Anusorn Thanataveerat, Keane Y Tzong, Juyang Xiong, Miao Wang, Dong Zhao, Lee Goldman and Andrew E Moran

Vitamin D and Risk of Multiple Sclerosis: A Mendelian Randomization Study pp. 1-20

Lauren E Mokry, Stephanie Ross, Omar S Ahmad, Vincenzo Forgetta, George Davey Smith, Aaron Leong, Celia M T Greenwood, George Thanassoulis and J Brent Richards

Antipsychotic Maintenance Treatment: Time to Rethink? pp. 1-7

Joanna Moncrieff

Point-of-Care Information in Open Access: A Time to Sow? pp. 1-3

The PLOS Medicine Editors

The Impact of a One-Dose versus Two-Dose Oral Cholera Vaccine Regimen in Outbreak Settings: A Modeling Study pp. 1-18

Andrew S Azman, Francisco J Luquero, Iza Ciglenecki, Rebecca F Grais, David A Sack and Justin Lessler

Open Access to a High-Quality, Impartial, Point-of-Care Medical Summary Would Save Lives: Why Does It Not Exist? pp. 1-8

James Heilman

The Polypill: From Promise to Pragmatism pp. 1-6

Mark D Huffman

Volume 12, issue 7, 2015

Noncommunicable Diseases: A Globalization of Disparity? pp. 1-4

Peter J Hotez and Larry Peiperl

Risk of Adverse Pregnancy Outcomes among Women Practicing Poor Sanitation in Rural India: A Population-Based Prospective Cohort Study pp. 1-18

Bijaya K Padhi, Kelly K Baker, Ambarish Dutta, Oliver Cumming, Matthew C Freeman, Radhanatha Satpathy, Bhabani S Das and Pinaki Panigrahi

Glitazone Treatment and Incidence of Parkinson’s Disease among People with Diabetes: A Retrospective Cohort Study pp. 1-16

Ruth Brauer, Krishnan Bhaskaran, Nishi Chaturvedi, David T Dexter, Liam Smeeth and Ian Douglas

Individual Participant Data (IPD) Meta-analyses of Randomised Controlled Trials: Guidance on Their Use pp. 1-16

Jayne F Tierney, Claire Vale, Richard Riley, Catrin Tudur Smith, Lesley Stewart, Mike Clarke and Maroeska Rovers

Searching for Public Health Law’s Sweet Spot: The Regulation of Sugar-Sweetened Beverages pp. 1-10

David M Studdert, Jordan Flanders and Michelle M Mello

Health, Health Inequality, and Cost Impacts of Annual Increases in Tobacco Tax: Multistate Life Table Modeling in New Zealand pp. 1-21

Tony Blakely, Linda J Cobiac, Christine L Cleghorn, Amber L Pearson, Frederieke S van der Deen, Giorgi Kvizhinadze, Nhung Nghiem, Melissa McLeod and Nick Wilson

Volume 12, issue 6, 2015

Inequitable and Ineffective: Exclusion of Mental Health from the Post-2015 Development Agenda pp. 1-4

Alexander C Tsai and Mark Tomlinson

Mistreatment of Women in Childbirth: Time for Action on This Important Dimension of Violence against Women pp. 1-4

Rachel Jewkes and Loveday Penn-Kekana

Assessing Development Assistance for Mental Health in Developing Countries: 2007–2013 pp. 1-10

Barnabas J Gilbert, Vikram Patel, Paul E Farmer and Chunling Lu

Achieving Systemic and Scalable Private Sector Engagement in Tuberculosis Care and Prevention in Asia pp. 1-10

William A Wells, Mukund Uplekar and Madhukar Pai

HIV Programs for Sex Workers: Lessons and Challenges for Developing and Delivering Programs pp. 1-11

David Wilson

Exposure to Second-Hand Smoke and the Risk of Tuberculosis in Children and Adults: A Systematic Review and Meta-Analysis of 18 Observational Studies pp. 1-21

Jayadeep Patra, Mehak Bhatia, Wilson Suraweera, Shaun K Morris, Cyril Patra, Prakash C Gupta and Prabhat Jha

The Mistreatment of Women during Childbirth in Health Facilities Globally: A Mixed-Methods Systematic Review pp. 1-32

Meghan A Bohren, Joshua P Vogel, Erin C Hunter, Olha Lutsiv, Suprita K Makh, João Paulo Souza, Carolina Aguiar, Fernando Saraiva Coneglian, Alex Luíz Araújo Diniz, Özge Tunçalp, Dena Javadi, Olufemi T Oladapo, Rajat Khosla, Michelle J Hindin and A Metin Gülmezoglu

Volume 12, issue 5, 2015

Seasonal Influenza Vaccination for Children in Thailand: A Cost-Effectiveness Analysis pp. 1-25

Aronrag Meeyai, Naiyana Praditsitthikorn, Surachai Kotirum, Wantanee Kulpeng, Weerasak Putthasri, Ben S Cooper and Yot Teerawattananon

A Global Biomedical R&D Fund and Mechanism for Innovations of Public Health Importance pp. 1-4

Manica Balasegaram, Christian Bréchot, Jeremy Farrar, David Heymann, Nirmal Ganguly, Martin Khor, Yves Lévy, Precious Matsoso, Ren Minghui, Bernard Pécoul, Liu Peilong, Marcel Tanner and John-Arne Røttingen

Setting International Standards for the Management of Public Health Pesticides pp. 1-9

Henk van den Berg, Rajpal Singh Yadav and Morteza Zaim

Healthy Eating and Risks of Total and Cause-Specific Death among Low-Income Populations of African-Americans and Other Adults in the Southeastern United States: A Prospective Cohort Study pp. 1-17

Danxia Yu, Jennifer Sonderman, Maciej S Buchowski, Joseph K McLaughlin, Xiao-Ou Shu, Mark Steinwandel, Lisa B Signorello, Xianglan Zhang, Margaret K Hargreaves, William J Blot and Wei Zheng

How Has the Age-Related Process of Overweight or Obesity Development Changed over Time? Co-ordinated Analyses of Individual Participant Data from Five United Kingdom Birth Cohorts pp. 1-20

William Johnson, Leah Li, Diana Kuh and Rebecca Hardy

The Health System and Population Health Implications of Large-Scale Diabetes Screening in India: A Microsimulation Model of Alternative Approaches pp. 1-21

Sanjay Basu, Christopher Millett, Sandeep Vijan, Rodney A Hayward, Sanjay Kinra, Rahoul Ahuja and John S Yudkin

Volume 12, issue 4, 2015

Geographic and Temporal Trends in the Molecular Epidemiology and Genetic Mechanisms of Transmitted HIV-1 Drug Resistance: An Individual-Patient- and Sequence-Level Meta-Analysis pp. 1-29

Soo-Yon Rhee, Jose Luis Blanco, Michael R Jordan, Jonathan Taylor, Philippe Lemey, Vici Varghese, Raph L Hamers, Silvia Bertagnolio, Tobias F Rinke de Wit, Avelin F Aghokeng, Jan Albert, Radko Avi, Santiago Avila-Rios, Pascal O Bessong, James I Brooks, Charles A B Boucher, Zabrina L Brumme, Michael P Busch, Hermann Bussmann, Marie-Laure Chaix, Bum Sik Chin, Toni T D’Aquin, Cillian F De Gascun, Anne Derache, Diane Descamps, Alaka K Deshpande, Cyrille F Djoko, Susan H Eshleman, Herve Fleury, Pierre Frange, Seiichiro Fujisaki, P Richard Harrigan, Junko Hattori, Africa Holguin, Gillian M Hunt, Hiroshi Ichimura, Pontiano Kaleebu, David Katzenstein, Sasisopin Kiertiburanakul, Jerome H Kim, Sung Soon Kim, Yanpeng Li, Irja Lutsar, Lynn Morris, Nicaise Ndembi, Kee Peng Ng, Ramesh S Paranjape, Martine Peeters, Mario Poljak, Matt A Price, Manon L Ragonnet-Cronin, Gustavo Reyes-Terán, Morgane Rolland, Sunee Sirivichayakul, Davey M Smith, Marcelo A Soares, Vincent V Soriano, Deogratius Ssemwanga, Maja Stanojevic, Mariane A Stefani, Wataru Sugiura, Somnuek Sungkanuparph, Amilcar Tanuri, Kok Keng Tee, Hong-Ha M Truong, David A M C van de Vijver, Nicole Vidal, Chunfu Yang, Rongge Yang, Gonzalo Yebra, John P A Ioannidis, Anne-Mieke Vandamme and Robert W Shafer

Defining the In Vivo Phenotype of Artemisinin-Resistant Falciparum Malaria: A Modelling Approach pp. 1-17

Lisa J White, Jennifer A Flegg, Aung Pyae Phyo, Ja Hser Wiladpai-ngern, Delia Bethell, Christopher Plowe, Tim Anderson, Standwell Nkhoma, Shalini Nair, Rupam Tripura, Kasia Stepniewska, Wirichada Pan-Ngum, Kamolrat Silamut, Ben S Cooper, Yoel Lubell, Elizabeth A Ashley, Chea Nguon, François Nosten, Nicholas J White and Arjen M Dondorp

Evaluating Clinical Trial Designs for Investigational Treatments of Ebola Virus Disease pp. 1-14

Ben S Cooper, Maciej F Boni, Wirichada Pan-ngum, Nicholas P J Day, Peter W Horby, Piero Olliaro, Trudie Lang, Nicholas J White, Lisa J White and John Whitehead

Rationale for WHO's New Position Calling for Prompt Reporting and Public Disclosure of Interventional Clinical Trial Results pp. 1-4

Vasee S Moorthy, Ghassan Karam, Kirsten S Vannice and Marie-Paule Kieny

Bringing Access to the Full Spectrum of Cancer Research: A Call for Papers pp. 1-3

The PLOS Medicine Editors

Volume 12, issue 3, 2015

Role of Acute HIV Infection in Driving HIV Transmission: Implications for HIV Treatment as Prevention pp. 1-4

Laith J Abu-Raddad

Testing and Treating the Missing Millions with Tuberculosis pp. 1-3

Madhukar Pai and Puneet Dewan

Strengthening the Detection of and Early Response to Public Health Emergencies: Lessons from the West African Ebola Epidemic pp. 1-8

Mark J Siedner, Lawrence O Gostin, Hilarie H Cranmer and John D Kraemer

Reassessment of HIV-1 Acute Phase Infectivity: Accounting for Heterogeneity and Study Design with Simulated Cohorts pp. 1-28

Steve E Bellan, Jonathan Dushoff, Alison P Galvani and Lauren Ancel Meyers

UK Biobank: An Open Access Resource for Identifying the Causes of a Wide Range of Complex Diseases of Middle and Old Age pp. 1-10

Cathie Sudlow, John Gallacher, Naomi Allen, Valerie Beral, Paul Burton, John Danesh, Paul Downey, Paul Elliott, Jane Green, Martin Landray, Bette Liu, Paul Matthews, Giok Ong, Jill Pell, Alan Silman, Alan Young, Tim Sprosen, Tim Peakman and Rory Collins

Paying Physicians to Prescribe Generic Drugs and Follow-On Biologics in the United States pp. 1-10

Ameet Sarpatwari, Niteesh K Choudhry, Jerry Avorn and Aaron S Kesselheim

A Public Health Approach to Hepatitis C Control in Low- and Middle-Income Countries pp. 1-12

Amitabh B Suthar and Anthony D Harries

Sugar Industry Influence on the Scientific Agenda of the National Institute of Dental Research’s 1971 National Caries Program: A Historical Analysis of Internal Documents pp. 1-22

Cristin E Kearns, Stanton A Glantz and Laura A Schmidt

Volume 12, issue 2, 2015

A Primary Care Nurse-Delivered Walking Intervention in Older Adults: PACE (Pedometer Accelerometer Consultation Evaluation)-Lift Cluster Randomised Controlled Trial pp. 1-23

Tess Harris, Sally M Kerry, Christina R Victor, Ulf Ekelund, Alison Woodcock, Steve Iliffe, Peter H Whincup, Carole Beighton, Michael Ussher, Elizabeth S Limb, Lee David, Debbie Brewin, Fredrika Adams, Annabelle Rogers and Derek G Cook

Open Access to Large Scale Datasets Is Needed to Translate Knowledge of Cancer Heterogeneity into Better Patient Outcomes pp. 1-4

Andrew H Beck

Enabling Dynamic Partnerships through Joint Degrees between Low- and High-Income Countries for Capacity Development in Global Health Research: Experience from the Karolinska Institutet/Makerere University Partnership pp. 1-8

Nelson Sewankambo, James K Tumwine, Göran Tomson, Celestino Obua, Freddie Bwanga, Peter Waiswa, Elly Katabira, Hannah Akuffo, Kristina Persson and Stefan Peterson

Volume 12, issue 1, 2015

Hormonal Contraception and the Risk of HIV Acquisition: An Individual Participant Data Meta-analysis pp. 1-26

Charles S Morrison, Pai-Lien Chen, Cynthia Kwok, Jared M Baeten, Joelle Brown, Angela M Crook, Lut Van Damme, Sinead Delany-Moretlwe, Suzanna C Francis, Barbara A Friedland, Richard J Hayes, Renee Heffron, Saidi Kapiga, Quarraisha Abdool Karim, Stephanie Karpoff, Rupert Kaul, R Scott McClelland, Sheena McCormack, Nuala McGrath, Landon Myer, Helen Rees, Ariane van der Straten, Deborah Watson-Jones, Janneke H H M van de Wijgert, Randy Stalter and Nicola Low

Supporting Those Who Go to Fight Ebola pp. 1-4

Michelle M Mello, Maria W Merritt and Scott D Halpern

Randomized Controlled Trials in Environmental Health Research: Unethical or Underutilized? pp. 1-5

Ryan W Allen, Prabjit K Barn and Bruce P Lanphear