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Statistical Applications in Genetics and Molecular Biology

2002 - 2020

Current editor(s): Michael P. H. Stumpf

From De Gruyter
Bibliographic data for series maintained by Peter Golla ().

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Volume 16, issue 5-6, 2017

Modifying SAMseq to account for asymmetry in the distribution of effect sizes when identifying differentially expressed genes pp. 291-312 Downloads
Kotoka Ekua and Orr Megan
A statistical method for analysing cospeciation in tritrophic ecology using electrical circuit theory pp. 313-331 Downloads
Nooney Colleen, Barber Stuart, Gusnanto Arief and Gilks Walter R.
A smoothed EM-algorithm for DNA methylation profiles from sequencing-based methods in cell lines or for a single cell type pp. 333-347 Downloads
Lakhal-Chaieb Lajmi, Greenwood Celia M.T., Ouhourane Mohamed, Zhao Kaiqiong, Abdous Belkacem and Oualkacha Karim
Multivariate association between single-nucleotide polymorphisms in Alzgene linkage regions and structural changes in the brain: discovery, refinement and validation pp. 349-365 Downloads
Szefer Elena, Graham Jinko, Lu Donghuan, Beg Mirza Faisal and Nathoo Farouk
Bayesian estimation of differential transcript usage from RNA-seq data pp. 367-386 Downloads
Papastamoulis Panagiotis and Rattray Magnus
Approximate maximum likelihood estimation for population genetic inference pp. 387-405 Downloads
Bertl Johanna, Ewing Gregory, Kosiol Carolin and Futschik Andreas
A Bayesian hierarchical model for identifying significant polygenic effects while controlling for confounding and repeated measures pp. 407-419 Downloads
McMahan Christopher, Bridges William, Joyner Chase, Lund Robert, Baurley James, Kacamarga Muhamad Fitra, Pardamean Carissa and Pardamean Bens

Volume 16, issue 4, 2017

FC1000: normalized gene expression changes of systematically perturbed human cells pp. 217-242 Downloads
Lönnstedt Ingrid M. and Nelander Sven
Bayesian comparison of protein structures using partial Procrustes distance pp. 243-257 Downloads
Ejlali Nasim, Faghihi Mohammad Reza and Sadeghi Mehdi
Confidence intervals for heritability via Haseman-Elston regression pp. 259-273 Downloads
Sofer Tamar
A statistical test for detecting parent-of-origin effects when parental information is missing pp. 275-289 Downloads
Sacco Chiara, Viroli Cinzia and Falchi Mario

Volume 16, issue 3, 2017

Regularized estimation in sparse high-dimensional multivariate regression, with application to a DNA methylation study pp. 159-171 Downloads
Zhang Haixiang, Zheng Yinan, Zhang Zhou, Gao Tao, Joyce Brian, Zhang Wei, Hou Lifang, Liu Lei, Yoon Grace, Schwartz Joel, Vokonas Pantel, Colicino Elena and Baccarelli Andrea
Mixture model-based association analysis with case-control data in genome wide association studies pp. 173-187 Downloads
Ali Fadhaa and Zhang Jian
Genetic association test based on principal component analysis pp. 189-198 Downloads
Chen Zhongxue, Han Shizhong and Wang Kai
Comparing the performance of linear and nonlinear principal components in the context of high-dimensional genomic data integration pp. 199-216 Downloads
Islam Shofiqul, Anand Sonia, Thabane Lehana, Hamid Jemila and Beyene Joseph

Volume 16, issue 2, 2017

Missing value imputation for gene expression data by tailored nearest neighbors pp. 95-106 Downloads
Faisal Shahla and Tutz Gerhard
A time warping approach to multiple sequence alignment pp. 133-144 Downloads
Arribas-Gil Ana and Matias Catherine
A Bayesian semiparametric factor analysis model for subtype identification pp. 145-158 Downloads
Sun Jiehuan, Warren Joshua L. and Zhao Hongyu

Volume 16, issue 1, 2017

Statistical models and computational algorithms for discovering relationships in microbiome data pp. 1-12 Downloads
Shaikh Mateen R. and Beyene Joseph
Binary Markov Random Fields and interpretable mass spectra discrimination pp. 13-30 Downloads
Kong Ao and Azencott Robert
Comparison and visualisation of agreement for paired lists of rankings pp. 31-45 Downloads
Donald Margaret R. and Wilson Susan R.
Bivariate Poisson models with varying offsets: an application to the paired mitochondrial DNA dataset pp. 47-58 Downloads
Su Pei-Fang, Mau Yu-Lin, Li Chung-I, Guo Yan, Liu Qi, Shyr Yu and Boice John D.
Generalized partial linear varying multi-index coefficient model for gene-environment interactions pp. 59-74 Downloads
Liu Xu, Gao Bin and Cui Yuehua
Polyunphased: an extension to polytomous outcomes of the Unphased package for family-based genetic association analysis pp. 75-81 Downloads
Bureau Alexandre and Croteau Jordie

Volume 15, issue 6, 2016

Estimating intrinsic and extrinsic noise from single-cell gene expression measurements pp. 447-471 Downloads
Fu Audrey Qiuyan and Pachter Lior
Tree-based quantitative trait mapping in the presence of external covariates pp. 473-490 Downloads
Thompson Katherine L., Linnen Catherine R. and Kubatko Laura
Sample size calculation based on generalized linear models for differential expression analysis in RNA-seq data pp. 491-505 Downloads
Li Chung-I and Shyr Yu
Adaptive input data transformation for improved network reconstruction with information theoretic algorithms pp. 507-520 Downloads
Kannan Venkateshan and Tegner Jesper

Volume 15, issue 5, 2016

Diagnostics for assessing the linear noise and moment closure approximations pp. 363-379 Downloads
Gillespie Colin S. and Golightly Andrew
Search of latent periodicity in amino acid sequences by means of genetic algorithm and dynamic programming pp. 381-400 Downloads
Pugacheva Valentina, Korotkov Alexander and Korotkov Eugene
A simulation framework for correlated count data of features subsets in high-throughput sequencing or proteomics experiments pp. 401-414 Downloads
Kruppa Jochen, Jung Klaus, Kramer Frank and Beißbarth Tim
Accounting for isotopic clustering in Fourier transform mass spectrometry data analysis for clinical diagnostic studies pp. 415-430 Downloads
Kakourou Alexia, Mertens Bart, Vach Werner, Nicolardi Simone and Yuri van der Burgt
Evaluation of low-template DNA profiles using peak heights pp. 431-445 Downloads
Steele Christopher D., Greenhalgh Matthew and Balding David J.

Volume 15, issue 4, 2016

Bayesian state space models for dynamic genetic network construction across multiple tissues pp. 273-290 Downloads
Liang Yulan and Kelemen Arpad
A joint modeling approach for uncovering associations between gene expression, bioactivity and chemical structure in early drug discovery to guide lead selection and genomic biomarker development pp. 291-304 Downloads
Perualila-Tan Nolen, Shkedy Ziv, Kasim Adetayo, Talloen Willem, Verbist Bie, Göhlmann Hinrich W.H. and Consortium Qstar
The use of vector bootstrapping to improve variable selection precision in Lasso models pp. 305-320 Downloads
Laurin Charles, Boomsma Dorret and Lubke Gitta
Finding causative genes from high-dimensional data: an appraisal of statistical and machine learning approaches pp. 321-347 Downloads
Wang Chamont and Gevertz Jana L.
LandScape: a simple method to aggregate p-values and other stochastic variables without a priori grouping pp. 349-361 Downloads
Wiuf Carsten, Schaumburg-Müller Pallesen Jonatan, Foldager Leslie and Grove Jakob

Volume 15, issue 3, 2016

Model selection for factorial Gaussian graphical models with an application to dynamic regulatory networks pp. 193-212 Downloads
Vinciotti Veronica, Augugliaro Luigi, Abbruzzo Antonino and Wit Ernst C.
Testing differentially expressed genes in dose-response studies and with ordinal phenotypes pp. 213-235 Downloads
Sweeney Elizabeth, Crainiceanu Ciprian and Gertheiss Jan
Differential methylation tests of regulatory regions pp. 237-251 Downloads
Ryu Duchwan, Xu Hongyan, George Varghese, Su Shaoyong, Wang Xiaoling, Shi Huidong and Podolsky Robert H.
Sparse factor model for co-expression networks with an application using prior biological knowledge pp. 253-272 Downloads
Blum Yuna, Houée-Bigot Magalie and Causeur David

Volume 15, issue 2, 2016

What if we ignore the random effects when analyzing RNA-seq data in a multifactor experiment pp. 87-105 Downloads
Cui Shiqi, Ji Tieming, Li Jilong, Cheng Jianlin and Qiu Jing
A graph theoretical approach to data fusion pp. 107-122 Downloads
Žurauskienė Justina, Kirk Paul D.W. and Stumpf Michael P.H.
Resistant multiple sparse canonical correlation pp. 123-138 Downloads
Coleman Jacob, Replogle Joseph, Chandler Gabriel and Hardin Johanna
A Markov random field-based approach for joint estimation of differentially expressed genes in mouse transcriptome data pp. 139-150 Downloads
Lin Zhixiang, Li Mingfeng, Sestan Nenad and Zhao Hongyu
AGGrEGATOr: A Gene-based GEne-Gene interActTiOn test for case-control association studies pp. 151-171 Downloads
Emily Mathieu
Comparing five statistical methods of differential methylation identification using bisulfite sequencing data pp. 173-191 Downloads
Yu Xiaoqing and Sun Shuying

Volume 15, issue 1, 2016

Identification of consistent functional genetic modules pp. 1-18 Downloads
Miecznikowski Jeffrey C., Gaile Daniel P., Chen Xiwei and Tritchler David L.
Using persistent homology and dynamical distances to analyze protein binding pp. 19-38 Downloads
Kovacev-Nikolic Violeta, Bubenik Peter, Nikolić Dragan and Heo Giseon
Belief propagation in genotype-phenotype networks pp. 39-53 Downloads
Moharil Janhavi, May Paul, Gaile Daniel P. and Blair Rachael Hageman
HMM-Fisher: identifying differential methylation using a hidden Markov model and Fisher’s exact test pp. 55-67 Downloads
Sun Shuying and Yu Xiaoqing
HMM-DM: identifying differentially methylated regions using a hidden Markov model pp. 69-81 Downloads
Yu Xiaoqing and Sun Shuying
MDI-GPU: accelerating integrative modelling for genomic-scale data using GP-GPU computing pp. 83-86 Downloads
Mason Samuel A., Wild David L., Sayyid Faiz, Kirk Paul D.W. and Starr Colin
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