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Statistical Applications in Genetics and Molecular Biology

2002 - 2024

Current editor(s): Michael P. H. Stumpf

From De Gruyter
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Volume 9, issue 1, 2010

An Alternative Model of Type A Dependence in a Gene Set of Correlated Genes pp. 12 Downloads
Lim Johan, Kim Jayeon and Kim Byung Soo
The Generalized Odds Ratio as a Measure of Genetic Risk Effect in the Analysis and Meta-Analysis of Association Studies pp. 14 Downloads
Zintzaras Elias
Classification of Genomic Sequences via Wavelet Variance and a Self-Organizing Map with an Application to Mitochondrial DNA pp. 14 Downloads
Jach Agnieszka E and Marín Juan M
On Optimal Selection of Summary Statistics for Approximate Bayesian Computation pp. 16 Downloads
Nunes Matthew A and Balding David J
Permutation P-values Should Never Be Zero: Calculating Exact P-values When Permutations Are Randomly Drawn pp. 16 Downloads
Phipson Belinda and Smyth Gordon K
On the Optimal Design of Genetic Variant Discovery Studies pp. 17 Downloads
Ionita-Laza Iuliana and Laird Nan M
Detecting Genotyping Error Using Measures of Degree of Hardy-Weinberg Disequilibrium pp. 17 Downloads
Attia John, Thakkinstian Ammarin, McElduff Patrick, Milne Elizabeth, Dawson Somer, Scott Rodney J, Klerk Nicholas de, Armstrong Bruce and Thompson John
The Detection of Blur in Affymetrix GeneChips pp. 19 Downloads
Upton Graham J. G. and Harrison Andrew P
A Bayesian Hierarchical Model for Quantitative Real-Time PCR Data pp. 21 Downloads
Follestad Turid, Jørstad Tommy S, Erlandsen Sten E, Sandvik Arne K, Bones Atle M and Langaas Mette
Mapping Quantitative Trait Loci in a Non-Equilibrium Population pp. 21 Downloads
Wu Song, Yang Jie and Wu Rongling
Comparing Spatial Maps of Human Population-Genetic Variation Using Procrustes Analysis pp. 22 Downloads
Wang Chaolong, Szpiech Zachary A, Degnan James H, Jakobsson Mattias, Pemberton Trevor J, Hardy John A, Singleton Andrew B and Rosenberg Noah A
Dealing with Heterogeneity between Cohorts in Genomewide SNP Association Studies pp. 22 Downloads
Lebrec Jeremie J, Stijnen Theo and C van Houwelingen Hans
An Internal Calibration Method for Protein-Array Studies pp. 23 Downloads
Daly Don Simone, Anderson Kevin K, Seurynck-Servoss Shannon L, Gonzalez Rachel M, White Amanda M and Zangar Richard C
Confidently Estimating the Number of DNA Replication Origins pp. 23 Downloads
Bhaskar Anand and Keich Uri
Regression-Based Multi-Trait QTL Mapping Using a Structural Equation Model pp. 23 Downloads
Mi Xiaojuan, Eskridge Kent, Wang Dong, Baenziger P. Stephen, Campbell B. Todd, Gill Kulvinder S., Dweikat Ismail and Bovaird James
Predicting Patient Survival from Longitudinal Gene Expression pp. 23 Downloads
Zhang Yuping, Tibshirani Robert J. and Davis Ronald W.
Epistatic Interactions pp. 24 Downloads
VanderWeele Tyler J
Trilocus Disequilibrium Analysis of Multiallelic Markers in Outcrossing Populations pp. 24 Downloads
Berg Arthur, He Qiuling, Shen Ye, Chen Ying, Huang Minren and Wu Rongling
Granger Causality Analysis of Human Cell-Cycle Gene Expression Profiles pp. 24 Downloads
Nagarajan Radhakrishnan and Upreti Meenakshi
Asymptotic Distribution of the "Orthogonal" Quantitative Transmission Disequilibrium Test in a Structured Population: Exact Formula pp. 25 Downloads
Boitard Simon, Mangin Brigitte and Azaïs Jean-Marc
Space Oriented Rank-Based Data Integration pp. 25 Downloads
Lin Shili
Spatial Clustering of Array CGH Features in Combination with Hierarchical Multiple Testing pp. 25 Downloads
Kim Kyung In, Roquain Etienne and A van de Wiel Mark
Including Probe-Level Measurement Error in Robust Mixture Clustering of Replicated Microarray Gene Expression pp. 25 Downloads
Liu Xuejun and Rattray Magnus
Reconstructability Analysis as a Tool for Identifying Gene-Gene Interactions in Studies of Human Diseases pp. 27 Downloads
Shervais Stephen, Kramer Patricia L, Westaway Shawn K., Cox Nancy J and Zwick Martin
Locating Multiple Interacting Quantitative Trait Loci with the Zero-Inflated Generalized Poisson Regression pp. 27 Downloads
Erhardt Vinzenz, Bogdan Malgorzata and Czado Claudia
Optimisation of HMM Topologies Enhances DNA and Protein Sequence Modelling pp. 27 Downloads
Friedrich Torben, Koetschan Christian and Müller Tobias
An Empirical Bayesian Method for Estimating Biological Networks from Temporal Microarray Data pp. 28 Downloads
Rau Andrea, Jaffrézic Florence, Foulley Jean-Louis and Doerge Rebecca W
Weighted-LASSO for Structured Network Inference from Time Course Data pp. 29 Downloads
Charbonnier Camille, Chiquet Julien and Ambroise Christophe
Testing for Gene-Gene Interaction with AMMI Models pp. 29 Downloads
Barhdadi Amina and Dubé Marie-Pierre
A Random Coefficients Model for Regional Co-Expression Associated with DNA Copy Number pp. 30 Downloads
N van Wieringen Wessel, Berkhof Johannes and A van de Wiel Mark
Lasso Logistic Regression, GSoft and the Cyclic Coordinate Descent Algorithm: Application to Gene Expression Data pp. 30 Downloads
Garcia-Magariños Manuel, Antoniadis Anestis, Cao Ricardo and González-Manteiga Wenceslao
Generalizing Moving Averages for Tiling Arrays Using Combined P-Value Statistics pp. 31 Downloads
Kechris Katerina J, Biehs Brian and Kornberg Thomas B
Informative or Noninformative Calls for Gene Expression: A Latent Variable Approach pp. 31 Downloads
Kasim Adetayo, Lin Dan, Suzy Van Sanden, Clevert Djork-Arné, Bijnens Luc, Göhlmann Hinrich, Amaratunga Dhammika, Hochreiter Sepp, Shkedy Ziv and Talloen Willem
Sparse Partial Least Squares Classification for High Dimensional Data pp. 32 Downloads
Chung Dongjun and Keles Sunduz
Shrinkage Estimation of Effect Sizes as an Alternative to Hypothesis Testing Followed by Estimation in High-Dimensional Biology: Applications to Differential Gene Expression pp. 33 Downloads
Montazeri Zahra, Yanofsky Corey M. and Bickel David R.
Buckley-James Boosting for Survival Analysis with High-Dimensional Biomarker Data pp. 33 Downloads
Wang Zhu and Wang C.Y.
The Apportionment of Total Genetic Variation by Categorical Analysis of Variance pp. 34 Downloads
Khang Tsung Fei and Yap Von Bing
Optimal Tests Shrinking Both Means and Variances Applicable to Microarray Data Analysis pp. 35 Downloads
Hwang J.T. Gene and Liu Peng
Network Enrichment Analysis in Complex Experiments pp. 36 Downloads
Shojaie Ali and Michailidis George
Parameter Estimation in Multiple-Hidden I.I.D. Models from Biological Multiple Alignment pp. 37 Downloads
Arribas-Gil Ana
Sub-Modular Resolution Analysis by Network Mixture Models pp. 43 Downloads
Marras Elisabetta, Travaglione Antonella and Capobianco Enrico
Assessment of LD Matrix Measures for the Analysis of Biological Pathway Association pp. 46 Downloads
Crosslin David R., Qin Xuejun and Hauser Elizabeth R.

Volume 8, issue 1, 2009

Increase of Rejection Rate in Case-Control Studies with the Differential Genotyping Error Rates pp. 11 Downloads
Ahn Kwangmi, Gordon Derek and Finch Stephen J
A Parametric Model for Analyzing Anticipation in Genetically Predisposed Families pp. 13 Downloads
Larsen Klaus, Petersen Janne, Bernstein Inge and Nilbert Mef
Multilevel Comparison of Dendrograms: A New Method with an Application for Genetic Classifications pp. 16 Downloads
Podani János, Engloner Attila and Major Agnes
Modified FDR Controlling Procedure for Multi-Stage Analyses pp. 17 Downloads
Tuglus Catherine and J. van der Laan Mark
Transmission Disequilibrium Test Power and Sample Size in the Presence of Locus Heterogeneity pp. 18 Downloads
Chen Chuanwen, Yang Guang, Buyske Steven, Matise Tara, Finch Stephen J and Gordon Derek
Impact of Population Stratification on Family-Based Association Tests with Longitudinal Measurements pp. 19 Downloads
Ding Xiao, Weiss Scott, Raby Benjamin, Lange Christoph and Laird Nan M
Univariate Shrinkage in the Cox Model for High Dimensional Data pp. 20 Downloads
Tibshirani Robert J.
A Unified Mixed Effects Model for Gene Set Analysis of Time Course Microarray Experiments pp. 20 Downloads
Wang Lily, Chen Xi, Wolfinger Russell D, Franklin Jeffrey L, Coffey Robert J and Zhang Bing
Balanced Gradient Boosting from Imbalanced Data for Clinical Outcome Prediction pp. 21 Downloads
Teramoto Reiji
Incorporating Duplicate Genotype Data into Linear Trend Tests of Genetic Association: Methods and Cost-Effectiveness pp. 22 Downloads
Borchers Bryce, Brown Marshall, McLellan Brian, Bekmetjev Airat and Tintle Nathan L
Adaptive Transmission Disequilibrium Test for Family Trio Design pp. 22 Downloads
Yuan Min, Tian Xin, Zheng Gang and Yang Yaning
Model Selection Based on FDR-Thresholding Optimizing the Area under the ROC-Curve pp. 22 Downloads
Graf Alexandra C. and Bauer Peter
M-quantile Regression Analysis of Temporal Gene Expression Data pp. 22 Downloads
Vinciotti Veronica and Yu Keming
Composite Likelihood Modeling of Neighboring Site Correlations of DNA Sequence Substitution Rates pp. 22 Downloads
Deng Ling and Moore Dirk F.
Characterizing the D2 Statistic: Word Matches in Biological Sequences pp. 23 Downloads
Forêt Sylvain, Wilson Susan R and Burden Conrad J
Statistical Screening Method for Genetic Factors Influencing Susceptibility to Common Diseases in a Two-Stage Genome-Wide Association Study pp. 23 Downloads
Sato Yasunori, Laird Nan, Suganami Hideki, Hamada Chikuma, Niki Naoto, Yoshimura Isao and Yoshida Teruhiko
Survival Analysis with High-Dimensional Covariates: An Application in Microarray Studies pp. 24 Downloads
Engler David and Li Yi
Weighted Multiple Hypothesis Testing Procedures pp. 24 Downloads
Kang Guolian, Ye Keying, Liu Nianjun, Allison David B. and Gao Guimin
Estimation of Selection Intensity under Overdominance by Bayesian Methods pp. 24 Downloads
Buzbas Erkan Ozge, Joyce Paul and Abdo Zaid
A Statistical Model for Genetic Mapping of Viral Infection by Integrating Epidemiological Behavior pp. 24 Downloads
Li Yao, Berg Arthur, Chang Myron N, Du Ping, Ahn Kwangmi, Mauger David, Liao Duanping and Wu Rongling
Normalization Method for Transcriptional Studies of Heterogeneous Samples - Simultaneous Array Normalization and Identification of Equivalent Expression pp. 25 Downloads
Qin Li-Xuan and Satagopan Jaya M
Detecting Outlier Samples in Microarray Data pp. 26 Downloads
Shieh Albert D and Hung Yeung Sam
Rotation Testing in Gene Set Enrichment Analysis for Small Direct Comparison Experiments pp. 26 Downloads
Dørum Guro, Snipen Lars, Solheim Margrete and Sæbø Solve
A Multilocus Model for Constructing a Linkage Disequilibrium Map in Human Populations pp. 27 Downloads
Li Qin and Wu Rongling
A Nonlinear Mixed-Effects Model for Estimating Calibration Intervals for Unknown Concentrations in Two-Color Microarray Data with Spike-Ins pp. 27 Downloads
Thilakarathne Pushpike J, Verbeke Geert, Engelen Kristof and Marchal Kathleen
A Bayesian Analysis Strategy for Cross-Study Translation of Gene Expression Biomarkers pp. 28 Downloads
Lucas Joseph, Carvalho Carlos and West Mike
A Multivariate Growth Curve Model for Ranking Genes in Replicated Time Course Microarray Data pp. 28 Downloads
Hamid Jemila S and Beyene Joseph
Testing of Chromosomal Clumping of Gene Properties pp. 29 Downloads
Fernandez-Ricaud Luciano, Dalevi Daniel, Blomberg Anders and Nerman Olle
Bayesian Unsupervised Learning with Multiple Data Types pp. 29 Downloads
Agius Phaedra, Ying Yiming and Campbell Colin
Extensions of Sparse Canonical Correlation Analysis with Applications to Genomic Data pp. 29 Downloads
Witten Daniela M and Tibshirani Robert J.
Identifying Individuals in a Complex Mixture of DNA with Unknown Ancestry pp. 29 Downloads
Sampson Joshua and Zhao Hongyu
Modeling Dependence in Methylation Patterns with Application to Ovarian Carcinomas pp. 29 Downloads
Lacey Michelle R and Ehrlich Melanie
MC-Normalization: A Novel Method for Dye-Normalization of Two-Channel Microarray Data pp. 30 Downloads
Landfors Mattias, Fahlén Jessica and Rydén Patrik
A Regularized Regression Approach for Dissecting Genetic Conflicts that Increase Disease Risk in Pregnancy pp. 30 Downloads
Li Shaoyu, Lu Qing, Fu Wenjiang, Romero Roberto and Cui Yuehua
Calculating Asymptotic Significance Levels of the Constrained Likelihood Ratio Test with Application to Multivariate Genetic Linkage Analysis pp. 34 Downloads
Morris Nathan J, Elston Robert and Stein Catherine M
Sequential Analysis for Microarray Data Based on Sensitivity and Meta-Analysis pp. 35 Downloads
Marot Guillemette and Mayer Claus-Dieter
Sparse Canonical Correlation Analysis with Application to Genomic Data Integration pp. 36 Downloads
Parkhomenko Elena, Tritchler David and Beyene Joseph
Two-Stage Model-Based Clustering for Liquid Chromatography Mass Spectrometry Data Analysis pp. 36 Downloads
?uksza Marta, Kluge Bogus?aw, Ostrowski Jerzy, Karczmarski Jakub and Gambin Anna
Prediction of Motifs Based on a Repeated-Measures Model for Integrating Cross-Species Sequence and Expression Data pp. 36 Downloads
Siewert Elizabeth A and Kechris Katerina J
Score Statistics for Mapping Quantitative Trait Loci pp. 37 Downloads
Chang Myron N, Wu Rongling, Wu Samuel S and Casella George
Dimension Reduction of Microarray Data in the Presence of a Censored Survival Response: A Simulation Study pp. 40 Downloads
Nguyen Tuan S and Rojo Javier
Inferring Dynamic Genetic Networks with Low Order Independencies pp. 40 Downloads
Lèbre Sophie
Hypothesis Tests for Point-Mass Mixture Data with Application to `Omics Data with Many Zero Values pp. 45 Downloads
Taylor Sandra and Pollard Katherine
Ancestral Recombination Graphs under Non-Random Ascertainment, with Applications to Gene Mapping pp. 46 Downloads
Hössjer Ola, Hartman Linda and Humphreys Keith
A Non-Homogeneous Hidden-State Model on First Order Differences for Automatic Detection of Nucleosome Positions pp. 47 Downloads
Kuan Pei Fen, Huebert Dana, Gasch Audrey and Keles Sunduz
Orthology-Based Multilevel Modeling of Differentially Expressed Mouse and Human Gene Pairs pp. 49 Downloads
Ogorek Benjamin A and Stefanski Leonard A
A Multiple Testing Approach to High-Dimensional Association Studies with an Application to the Detection of Associations between Risk Factors of Heart Disease and Genetic Polymorphisms pp. 58 Downloads
Ferreira José A., Berkhof Johannes, Souverein Olga and Zwinderman Koos
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